Functional and Structural Proteins of the Nervous System : Proceedings of Two Symposia on Proteins of the Nervous System and Myelin Proteins Held As Part of the Third Meeting of the International Society of Neurochemistry in Budapest, Hungary, in July 197

This book is the proceedings of two symposia, on Proteins of the Nervous System and Myelin Proteins, held as part of the Third Meeting of the International Society of Neurochemistry in Budapest, July 1971. If confirmation of the utility for such a book was needed, it was obtained with the independent publication of a review on Proteins of the Nervous System (1) covering essentially the same ground. This review is an excellent collection of the earlier litera­ ture. The present volume summarizes the more recent advances in this field, and in addition covers those areas, glycoproteins and peptide hydrolases, which were not dealt with by Shooter and Einstein (1). We are most grateful to Miss V. Troeger for typing the man- scripts and to Mr. A. Landmann for assistance with photography. A.N. DAVISON I.G. MORGAN P. MANDEL (1) SHOOTER, E.M. and EINSTEIN, E.R., Ann. Rev. Biochem., 40 (1971) 635. Front Matter....Pages i-x Front Matter....Pages 1-1 Introductory Remarks....Pages 3-4 Chemistry and Biology of Two Brain-Specific Proteins, S-100 and 14-3-2....Pages 5-7 The Heterogeneity of the S-100 Protein Fraction....Pages 9-19 Immunological Studies of Brain Specific Protein....Pages 21-38 Brain Glycoprotein 10B: Further Evidence of the “Sign-Post” Role of Brain Glycoproteins in Cell Recognition, Its Change in Brain Tumor, and the Presence of a “Distance Factor”....Pages 39-52 Front Matter....Pages 53-53 Some Biochemical Aspects of Neurotubule and Neurofilament Proteins....Pages 55-67 Membrane Proteins of Catecholamine-Storing Vesicles in Adrenal Medulla and Sympathetic Nerves....Pages 69-81 Biological Properties of the Nerve Growth Factor....Pages 83-90 The Physical and Biological Properties of 7S and β-NGF from the Mouse Submaxillary Gland....Pages 91-97 Structural Studies of 2.5 S Mouse Submaxillary Gland Nerve Growth Factor....Pages 99-106 Front Matter....Pages 107-107 Biochemistry, Function, and Neuropathology of the Glycoproteins in Brain Tissue....Pages 109-133 Glycoproteins of the Synaptic Region....Pages 135-153 Front Matter....Pages 155-155 Separation and Characterization of Myelin Proteins....Pages 157-170 Proteolipids....Pages 171-199 Myelin Basic Proteins....Pages 201-214 The Chemical and Immunologic Properties of the Basic A1 Protein of Myelin....Pages 215-240 The Control of Myelin Synthesis and Inborn Errors of Metabolism....Pages 241-250 Isolation and Characterization of Myelin Protein from Adult Quaking Mice and its Similarity to Myelin Protein of Young Normal Mice....Pages 251-261 Myelin Enzymes and Protein Metabolism....Pages 263-273 Concluding Remarks....Pages 275-276 Back Matter....Pages 277-286