Four decades of vector biology at the University of Notre Dame : a scientific perspective

This important volume gives the reader a scientific perspective in a historical context, on the origin, growth, and contributions of the VBL. Since its founding, the VBL has played an important role in shaping the field of vector biology into what it is today and has served as the "mecca" of vector biologists throughout the world. Four Decades of Vector Biology at the University of Notre Dame: A Scientific Perspective is a tribute to the illustrious scholars produced at Notre Dame's VBL, who currently occupy highly visible leadership roles in both academia and government institutions around the globe. Four Decades of Vector Biology at the University of Notre Dame Contents Dedication and Acknowledgments Introduction 1— Isolation and Characterization of Mutations and Genetic Mapping in Aedes aegypti a— Morphological Mutations b— Allozymes c— Molecular Markers 2— Female Monogamy and Matrone: Sex and Physiological Mutations 3— Cytology: Genome Structure, Organization, and Evolution a— Comparative Karyotypes b— Giemsa C-Banding Patterns: Heterochromatin Differentiation c— Genome Size Variation i— Interspecific Variation ii— Intraspecific Variation d— Intra- and Interspecific Variation in Repetitive DNA Amount and Organization e— Chromosome Mapping of Repetitive DNA 4— Genetics of Chromosomal Rearrangements 5— Genetic Control: Evolution of the Concept 6— Seminar in Vector Genetics 7— Genetic Control: Principles and Mechanisms a— Sterile-Insect Technique (SIT) b— Chromosomal Translocations 8— Genetic Control: Applications a— The Delhi Project: WHO/ICMR b— The Mombasa Project: USAID 9— Population Genetics a— Allozymes b— Molecular Markers 10— The Aedes albopictus Saga: Physiological Characteristics, Population Genetics, and Temporal Cha... a— Photoperiodic Sensitivity b— Cold-Hardiness c— Allozyme Differentiation i— U.S. Populations ii— Native Populations iii— Geographic Origin of U.S. and Brazilian Populations iv— Temporal Changes in Genetic Structure d— Ribosomal DNA (rDNA) Intergenic Spacer (IGS) Length Variation i— Population Genetic Survey ii— Temporal Variation in rDNA Spacer Length iii— Inheritance of rDNA Spacer Region iv— Chromosome Mapping and Copy Number of rRNA Genes e— Mitochondrial DNA Restriction Fragment Length Variation i— Intraspecific Variation ii— Interspecific Variation iii— Dynamics of mtDNA Haplotypes in Laboratory Cage Populations f— Reproductive Differentiation: Cytoplasmic Incompatibility in Aedes albopictus g— Competition between U.S. Strains of Ae. albopictus and Ae. aegypti h— Vector Competence to Dengue-1 Virus i— Oral Susceptibility and Horizontal Transmission ii— Vertical Transmission iii— Midgut Basal Lamina Thickness and Virus Dissemination iv— Inheritance of Midgut Infection/Disseminated Infection v— Status of Ae. albopictus in U.S. 11— Vector Competence and Arboviral Ecology 12— Endocrinology and Reproductive Physiology 13— Research and Training Funding 14— Special VBL Resources and Facilities International Reference Centre (IRC). University of Notre Dame's Environmental Research Center (UNDERC). Mosquito Data Bank of the University of Notre Dame (MODABUND). St. Joseph County Mosquito Surveillance Program. Indiana State Department of Health and the Laboratory for Arbovirus Research and Surveillance—Univer... Externship/Internship in Arbovirology for D.V.M. Students. 15— Linkages of the VBL with Tropical Institutions 16— Vector Biology Courses and Visiting Scientist Program Epilogue Appendix 1— Vector Biology Faculty, University of Notre Dame, 1957–1999 Appendix 2— Postdoctoral Research Associates in Vector Biology/Parasitology since 1960 Appendix 3— Predoctoral Students in Vector Biology/Parasitology since 1961 Appendix 4— Undergraduate Students in Vector Biology since 1962 Appendix 5— Visiting Scientists/Professors and Guest Lecturers Relevant to Vector Biology at the Uni... A— Visiting Scientists/Professors B— Guest Lecturers References