Foundations of Clinical Research: Applications to Practice (Pearson New International Edition)

__Foundations of Clinical Research: Applications to Practice, 3/e__ serves as a comprehensive reference for a variety of research situations. This edition reflects the contemporary focus on evidence-based practice in health care, and the essential concepts for understanding analysis and research design. Expanded topics include measures of diagnostic accuracy, statistical estimates of validity and reliability, systematic reviews and meta-analysis, search strategies and critical appraisal of literature for clinical decision making and development of research. Written for those in the health professions, including physical therapy, occupational therapy, speech therapy, nursing, and exercise physiology, this text will be useful to developing clinicians, practitioners, graduate students and researchers. Cover Table of Contents Glossary A B C D E F G H I K L M N O P Q R S T U V W X Y Z 1. A Concept of Clinical Research 2. The Role of Theory in Clinical Research 3. Ethical Issues in Clinical Research 4. Principles of Measurement 5. Reliability of Measurements 6. Validity of Measurements 7. Asking the Research Question 8. Sampling 9. Validity in Experimental Design 10. Experimental Designs 11. Quasi-Experimental Designs 12. Single-Subject Designs 13. Exploratory Research: Observational Designs 14. Descriptive Research 15. Surveys and Questionnaires 16. Systematic Reviews and Meta-Analysis 17. Descriptive Statistics 18. Statistical Inference 19. Comparing Two Means: The t-Test 20. Comparing More Than Two Means: Analysis of Variance 21. Multiple Comparison Tests 22. Nonparametric Tests for Group Comparisons 23. Correlation 24. Regression 25. Measures of Association for Categorical Variables: Chi-Square 26. Statistical Measures of Reliability 27. Statistical Measures of Validity 28. Epidemiology: Measuring Risk 29. Multivariate Analysis 30. Data Management 31. Searching the Literature Appendix: Statistical Tables Appendix: Relating the Research Question to the Choice of Statistical Test Appendix: Power and Sample Size Appendix: Transformation of Data Appendix: Sample Informed Consent Form Index A B C D E F G H I J K L M N O P Q R S T U V W X Y Provides the foundations that are necessary for finding and interpreting research evidence across all healthcare professions. Revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, including the growing emphasis on evidence-based practice (EBP) that has become central to all of health care and the new vocabulary that is being integrated into research and practice across disciplines. There is also a new chapter on systematic reviews and meta-analysis as well as expanded content related to clinical decision making, including likelihood ratios, pretest and posttest probabilities, minimally important change and number needed to treat. For those in the health professions, including physical therapy, occupational therapy, speech therapy, nursing, and exercise physiology