Fortschritte der Chemie organischer Naturstoffe. 82 = Progress in the chemistry of organic natural products. 82

The book gives a hitherto unavailable overview on a huge class of – so far largely neglected – natural products, characterized by one common structural element, a biaryl axis. Covering more than 1300 references, this review mainly focuses on the isolation of these compounds from natural sources, their structural elucidation with special regard to the biaryl axis as a possible stereoelement, their biological activities, and on their biosynthetic origin. Informative summaries on stereochemical aspects connected to a stereogenic axis and on the determination of axial configurations are given, as well as some selected examples out of atroposelective total syntheses. Never has this subject been addressed in such a detailed way, especially not concerning the great variety of different structural subgroups. This book should find the way to the library of any scientist working in the field of natural product, since it provides data on an overwhelming number of naturally occurring substances. The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline Front Matter....Pages I-VII Biaryls in Nature: A Multi-Facetted Class of Stereochemically, Biosynthetically, and Pharmacologically Intriguing Secondary Metabolites....Pages 1-249 Back Matter....Pages 251-296