Fluid Dynamics As a Localizing Factor for Atherosclerosis : The Proceedings of a Symposium Held at Heidelberg, FRG, June 18–20, 1982

Recent evidence by S.M. Schwartz and G.K. Hansson (this volume) suggests that some of the endothelial cells in these area Front Matter....Pages I-X Opening Comments....Pages 1-2 Fluid Dynamic Approaches to Atherosclerosis....Pages 3-8 A Fluid-Dynamicist’s and a Physiologist’s Look at Arterial Flow and Arteriosclerosis....Pages 9-25 The Case for Fluid Dynamics as a Localizing Factor in Atherogenesis....Pages 26-37 Flow and Atherogenesis in the Human Carotid Bifurcation....Pages 38-45 Pulsating Flow in Distensible Models of Vascular Branches....Pages 46-50 Coronary Artery Geometry and Its Fluid Mechanical Implications....Pages 51-59 Flow Patterns in Model and Natural Branching Vessels....Pages 60-70 Geometric Effects on the Hemodynamic Environment of the Arterial Wall: A Basis for Geometric Risk Factors?....Pages 71-78 The Drainage of Transmural Flow and the Consequences of Its Insufficiency....Pages 79-86 Fluid Mechanical Factors in Macromolecular Transport by the Arterial Wall....Pages 87-90 The Role of Hydrodynamic Factors in Platelet Activation and Thrombotic Events: The Effects of Shear Stress of Short Duration....Pages 91-102 Microrheology of Thrombocyte Deposition: Effect of Stimulation, Flow Direction, and Red Cells....Pages 103-115 The Localization of Transient Subendothelial Water-Filled Blisters in the in Situ Rabbit Aorta as a Result of Reduction in Pressure....Pages 116-128 Influence of Convection and Vasoactive Agents on the Mass Transport Properties of the Arterial Wall....Pages 129-134 Haemodynamic Influences on Platelets in Haemostasis and Thrombosis....Pages 135-140 Effects of Antihypertensive Drugs and Blood Velocity....Pages 141-144 General Properties of Endothelial Cells....Pages 145-158 The Endothelium as a Mediating Factor in Transport Across the Arterial Wall....Pages 159-167 Morphology and Fluid-Dynamics of Endothelial Cells at the Site of Vascular Bifurcation....Pages 168-172 Location and Morphology of Hypertensive Lesions in Coronary Arteries of Dogs....Pages 173-181 Response of Vascular Endothelium to Unsteady Fluid Shear Stress in Vitro....Pages 182-187 Injury at the Vascular Surface....Pages 188-199 Cellular Participation in Atherogenesis: Selected Facets of Endothelium, Smooth Muscle, and the Peripheral Blood Monocyte....Pages 200-207 Evidence that High Flow Velocity and Endothelial Disruption Are Not the Principal Factors in Experimental Plaque Localization....Pages 208-211 Localization of Early Atherosclerotic Lesions in Carotid and Coronary Bifurcations in Humans — A Bifurcation of the High Shear Stress Hypothesis....Pages 212-215 Quantitative Arterial Wall Morphology....Pages 216-226 Back Matter....Pages 227-232