Fine Needle Aspiration of Bone Tumours: The Clinical, Radiological, Cytological Approach (Monographs in Clinical Cytology, Vol. 19)

In recent years, fine-needle aspiration cytology (FNAC) has become a widely accepted procedure in the diagnosis of bone lesions. Rapid progress in immunocytochemistry and molecular genetics has increased the role of FNAC in the investigation of primary bone lesions. The purpose of this book is to facilitate the cytological evaluation of FNA smears from skeletal lesions and to provide diagnostic criteria based on the combined evaluation of clinical data and radiographic and cytological features. The major aim is to thoroughly describe and illustrate the most common entities as well as the diagnostic use of ancillary techniques. A number of rare primary bone tumours/lesions are also illustrated. The selection of entities illustrated in this comprehensive manual is based mainly on experience with patients referred to the Musculoskeletal Centre in Lund, Sweden, which now comprises smear data from approximately 1000 skeletal tumours/lesions collected between 1966 and 2006. This publication will be a valuable resource for pathologists, cytopathologists, radiologists, oncologists and orthopaedic surgeons involved in the work-up and management of patients with bone lesions. asdforaekfc......Page 1 Contents......Page 6 Preface......Page 12 1. Epidemiology of Bone Tumours......Page 13 2. Radiological Investigation of Bone Tumours......Page 15 3. Morphological Diagnosis of Bone Tumours......Page 19 4. Cytology of Normal Constituents in Bone Aspirates and of Reactive Changes......Page 25 5. Cytological Features of Bone Tumours in FNA Smears I: Osteogenic Tumours......Page 30 6. Cytological Features of Bone Tumours in FNA Smears II: Cartilaginous Tumours......Page 43 7. Cytological Features of Bone Tumours in FNA Smears III: Ewing Family Tumours......Page 57 8. Cytological Features of Bone Tumours in FNA Smears IV: Notochordal Tumours......Page 63 9. Cytological Features of Bone Tumours in FNA Smears V: Giant-Cell Lesions......Page 67 10. Rare Targets for FNAC and Diagnostic Problems with Benign Tumours/Lesions with Variable Numbers of Osteoclast-Like Giant Cells......Page 74 11. Lymphohaematopoetic and Histiocytic Tumours......Page 77 12. Inflammatory Lesions......Page 85 13. Bone Metastases......Page 87 14. Fine Needle Aspiration as the First Diagnostic Modality for Spinal and Sacral Lesions......Page 93 References......Page 98 Index......Page 101