Fibrin Sealant in Operative Medicine : Volume 4 Plastic Surgery - Maxillofacial and Dental Surgery

Fibrin plays a prominent role in wound healing. It has a hemostatic effect, induces cellular response to wound damage, and, by forming strands to build a matrix, assists in neovascularization and fibroblast proliferation. The concept of using clotting substances from human blood for wound manage­ ment and to achieve hemostasis in bleeding parenchymatous organs can be traced to 1909, when Bergel [1] reported on the hemostatic effect offibrin powder. In 1915, Grey [3] employed fibrin to control bleeding in neurosurgical operations of the brain. A year later, Harvey [4] used fibrin patches to stop bleeding from parenchy­ matous organs in general surgery. It took more than two decades for this ingenious idea to be rediscovered. In 1940, Young and Medawar [8] reported on experimental nerve anastomosis by sealing. Similarly, Tarlov and Benjamin [7] reunited nerves with plasma clots in 1943. Tarlov improved the results obtained with clot anastomosing of nerves by avoiding tension at the nerve stumps. In 1944, Cronkite et al. [2] reported on an initial series of eight cases in which fibrinogen and thrombin had been used successfully for anchoring skin grafts. Front Matter....Pages I-XVI Front Matter....Pages 1-1 The Importance of Fibrin in Wound Repair....Pages 3-12 Fibrin Sealant and Its Modes of Application....Pages 13-26 Properties of Different Tissue Sealants with Special Emphasis on Fibrinogen-Based Preparations....Pages 27-38 Lysis and Absorption of Fibrin Sealant (Tissucol/Tisseel)....Pages 39-50 Preliminary Results of a Randomized Controlled Study on the Risk of Hepatitis Transmission of a Two-Component Fibrin Sealant (Tissucol/Tisseel)....Pages 51-59 Front Matter....Pages 61-61 The Use of Fibrin Sealant in Patients with Rhinophyma....Pages 63-70 Fibrin Sealing in Plastic Surgery....Pages 71-78 Tissue-Adhesion Techniques in the Treatment of Extensive Postoperative Cavities and Fistulae....Pages 79-84 Further Clinical Applications of Human Fibrin Sealant in Plastic Surgery....Pages 85-89 Fibrin Sealant (Tissucol/Tisseel) and Its Application in Plastic and Reconstructive Surgery....Pages 90-92 Specific Indications for Fibrin Glue in Plastic and Craniomaxillofacial Surgery....Pages 93-97 Fibrin Sealant in Burn Injuries — Experimental Study....Pages 98-103 Skin Grafting with Fibrin Sealant in Burns....Pages 104-109 Fibrin Sealing in the Treatment of Burn Wounds....Pages 110-115 Fibrin Sealing in Dupuytren’s Contracture....Pages 116-122 Fibrinogen Glue (Tissucol/Tisseel) Skin Transplants in Leg Ulcers....Pages 123-126 New Aspects of Haemangioma Treatment....Pages 127-132 Front Matter....Pages 133-133 Use of Tissucol (Tisseel) in Maxillofacial Surgery....Pages 135-140 New Methods of Fibrin Sealant (Tissucol/Tisseel) Application in Maxillofacial Surgery: The Use of Hydroxyapatite in Association with Human Fibrin Glue in Reconstructive Surgery....Pages 141-145 The Management of Dentogenous Bone Cysts Using Bankbone and Fibrin Sealant (Tisseel/Tissucol)....Pages 146-151 Front Matter....Pages 133-133 The Use of Fibrin Sealant in Various Maxillosurgical Indications....Pages 152-157 Application of Fibrin Adhesive in Closure of Oronasal Communications with the Help of Flap Glossoplasty....Pages 158-163 The Use of Fibrin Adhesive in Dental Practice....Pages 164-170 Wound Management in Oral Surgery Using the Fibrin Adhesion System (Tissucol/Tisseel)....Pages 171-177 Complications in Hemophilic Patients Under Conditions of Fibrin Sealing....Pages 178-182 The Use of Fibrin Sealant (Tissucol/Tisseel) in Periodontal Surgery: Clinical and Histological Evaluation....Pages 183-187 A Modified Operating Technique Using Fibrin Sealant for Major Cysts of the Jaw in the Vicinity of the Mandibular Nerve....Pages 188-194 Back Matter....Pages 195-196 v. 1 Otorhinolaryngology v. 2 Ophthalmology-neurosurgery v. 3 Gynaecology and obstetrics-urology v. 4 Plastic surgery-maxillofacial and dental surgery