Fever and antipyresis : the role of the nervous system

This book provides a detailed overview of the function of the nervous system in fever and its role in antipyresis. The volume opens with an introductory account of fever, its physiology and adaptive role, and explains the mechanisms of thermoregulation. Sufficient information about bacterial pyrogens, 'endogenous' pyrogenic cytokines, body temperature regulation and survival value of fever and its ubiquity is given to enable readers to follow the central nervous system's involvement. The book should enable graduate students and researchers in neuroscience and other disciplines to understand the impact of their studies in the overall processes of fever. It will also be of benefit to pharmacologists studying anti-pyretics and the central nervous system function of these drugs. Academic clinicians will find this a more comprehensive overview of fever than other available texts. Finally, the author challenges some well-established dogmas in this area and sets an agenda for future research.

This book provides a detailed overview of the function of the nervous system in fever and its role in antipyresis.

Clement Hamani

This book provides the readers a clear and complete view of the mechanisms of fever generation, antipyresis, and the role of the nervous system in both processes. The purpose is to present a synopsis of new and old concepts concerning many general aspects of fever, thermoregulation, antipyresis with a special focus on the role of the nervous system in these processes. The fast development of the sciences related to the brain function as well as a better understanding of the mechanisms linked to thermogenesis have changed the way healthcare professionals must look at fever nowadays. In this book, the authors meet their objectives, giving an update and complete review of important aspects related to the regulation of the temperature. Fever and antipyresis are topics with which healthcare professionals of all kinds have to deal very often. Thus, this book will be very useful to medical students, practitioners, researchers and all other professionals interested in a general complete overview as well as a better understanding of these phenomena. This book is composed of nine chapters and one appendix that considers the anatomical aspects of thermogenesis. The chapters cover various aspects of fever, thermogenesis, antipyresis, exogenous pyrogens, endogenous pyrogens, the concept of setpoint, the roles of the hypothalamus, limbic system, cerebral cortex in relation to the thermic regulation of the body and various other topics related to this area. This book will be of great interest to all professionals and students interested in learning more about fever. It gives an updated overview of the mechanisms of thermic regulation and some of its imbalances, with a large focus on the role of thenervous system in these processes.

This book provides a detailed overview of the function of the central nervous system (CNS) in fever and its role in combating fever (antipyresis). The volume opens with an introductory account of fever, its physiology and adaptive role, and explains the mechanisms of thermoregulation. It then provides information about bacterial pyrogens, "endogenous" pyrogenic cytokines, body temperature regulation and survival value of fever and its ubiquity, in order to enable readers to follow the CNS involvement. Finally, the author challenges some well established dogmas in this area and sets an agenda for future research. The book will help graduate students and researchers in neuroscience and other disciplines to understand the impact of their studies in the overall processes of fever. It will also be of benefit to pharmacologists studying antipyretics and the CNS function of these drugs. Academic clinicians will find this a more comprehensive overview of fever than other available texts. Keith E. Cooper. Includes Bibliographical References (p. 149-176) And Index.