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Fenner's Veterinary Virology 4E is the long awaited new edition of Veterinary Virology 3E which was published in 1999. Fully revised and updated by the new author team, Part I presents the fundamental principles of virology related to animal infection and disease and Part II addresses the clinical features, pathogenesis, diagnosis, epidemiology and prevention of individual diseases. New to this Edition* New author team - one main author to ensure that the book reads like an authored book but with the benefit of using experts to contribute to specific topics.* Text has been refocused - Part I has been condensed and where appropriate incorporated into Part II to make it more user friendly.* The number of figures have been increased and are now in full colour Key Features and Benefits · Fully revised and updated to include the latest information in the field of veterinary virology · Beautifully illustrated color figures throughout · Organized and current information provided by an expert team of authors Fenner’s Veterinary Virology 4 Copyright Page 5 Contents 8 Contributors 20 Acknowledgments 22 Part I: The Principles of Veterinary and Zoonotic Virology 24 Chapter 1. The Nature of Viruses 26 Introduction: A Brief History of Animal Virology 26 Characteristics of Viruses 29 Viral Morphology 33 Viral Taxonomy 37 Chapter 2. Virus Replication 44 Growth of viruses 44 Virus Replication 47 Quantitative Assays of Viruses 62 Special Case of Defective Interfering Mutants 64 Chapter 3. Pathogenesis of Viral Infections and Diseases 66 Interplay of Viral Virulence and Host Resistance, or Susceptibility Factors in Expression of Viral Diseases 66 Mechanisms of Viral Infection and Virus Dissemination 69 Mechanisms of Viral Injury and Disease 77 Virus-Induced Neoplasia 90 Chapter 4. Antiviral Immunity and Prophylaxis 98 Host Immunity to Viral Infections 98 Viral Mechanisms of Avoidance and Escape 109 Vaccines and Vaccination Against Viral Diseases 110 Other Strategies for Antiviral Prophylaxis and Treatment 121 Viruses as Vectors for Gene Therapy 122 Chapter 5. Laboratory Diagnosis of Viral Infections 124 Rationale for Specific Diagnosis 125 Collection, Packaging, and Transport of Specimens 128 Diagnosis of Viral Infections by Gross Evaluation and Histopathology 130 Methods of Detection of Viruses 130 Nucleic Acid (Viral Genomic) Sequencing 139 Detection and Quantitation of Virus-Specific Antibodies (Serologic Diagnosis) 140 Interpretation of Laboratory Findings 144 Chapter 6. Epidemiology and Control of Viral Diseases 148 Epidemiology of Viral Infections 148 Emerging Viral Diseases 159 Surveillance, Prevention, Control, and Eradication of Viral Diseases 165 Part II: Veterinary and Zoonotic Viruses 172 Chapter 7. Poxviridae 174 Properties of Poxviruses 175 Members of the Genus Orthopoxvirus 178 Members of the Genus Capripoxvirus 180 Members of the Genus Suipoxvirus 183 Members of the Genus Leporipoxvirus 183 Members of the Genus Molluscipoxvirus 184 Members of the Genus Yatapoxvirus 184 Members of the Genus Avipoxvirus 185 Members of the Genus Parapoxvirus 186 Poxviruses of Fish 187 Other Poxviruses 188 Chapter 8. Asfarviridae and Iridoviridae 190 Members of the Family Asfarviridae 190 Members of the Family Iridoviridae 195 Chapter 9. Herpesvirales 202 Properties of Herpesviruses 203 Members of the Family Herpesviridae, Subfamily Alphaherpesvirinae 207 Members of the Family Herpesviridae, Subfamily Betaherpesvirinae 218 Members of the Family Herpesviridae, Subfamily Gammaherpesvirinae 219 Unassigned Members of the Family Herpesviridae 221 Members of Families Alloherpesviridae and Malacoherpesviridae 222 Chapter 10. Adenoviridae 226 Properties of Adenoviruses 226 Members of the Genus Mastadenovirus 230 Members of the Genus Aviadenovirus 233 Members of the Genus Atadenovirus 233 Members of the Genus Siadenovirus 235 Other Adenoviruses 235 Chapter 11. Papillomaviridae and Polyomaviridae 236 Members of the Family Papillomaviridae 236 Members of the Family Polyomaviridae 244 Chapter 12. Parvoviridae 248 Properties of Parvoviruses 248 Members of the Genus Parvovirus 251 Members of the Genus Erythrovirus 257 Members of the Genus Amdovirus 257 Members of the Genus Dependovirus 258 Members of the Genus Bocavirus 258 Other Parvoviruses 258 Chapter 13. Circoviridae 260 Properties of Circoviruses 260 Beak and Feather Disease Virus 262 Other Avian Circoviruses 263 Porcine Circoviruses 263 Chicken Anemia Virus 265 Chapter 14. Retroviridae 266 Properties of Retroviruses 267 Members of the Subfamily Orthoretrovirinae, Genus Alpharetrovirus 274 Members of the Subfamily Orthoretrovirinae, Genus Betaretrovirus 279 Members of the Subfamily Orthoretrovirinae, Genus Gammaretrovirus 282 Members of the Subfamily Orthoretrovirinae, Genus Deltaretrovirus 287 Members of the Subfamily Orthoretrovirinae, Genus Epsilonretrovirus 289 Members of the Subfamily Orthoretrovirinae, Genus Lentivirus 289 Members of the Subfamily Spumaretrovirinae 296 Miscellaneous Retrovirus-Associated Diseases 297 Chapter 15. Reoviridae 298 Properties of Reoviruses 299 Members of the Genus Orthoreovirus 304 Members of the Genus Orbivirus 306 Members of the Genus Rotavirus 311 Members of the Genus Coltivirus 313 Members of the Genus Aquareovirus 313 Other Reoviruses 314 Chapter 16. Birnaviridae 316 Properties of Birnaviruses 316 Infectious Bursal Disease Virus 318 Infectious Pancreatic Necrosis Virus 320 Chapter 17. Paramyxoviridae 322 Properties of Paramyxoviruses 324 Members of the Subfamily Paramyxovirinae, Genus Respirovirus 331 Members of the Subfamily Paramyxovirinae, Genus Rubulavirus 333 Members of the Subfamily Paramyxovirinae, Genus avulavirus 334 Members of the Subfamily Paramyxovirinae, Genus Morbillivirus 337 Members of the Subfamily Paramyxovirinae, Genus Henipavirus 344 Members of the Subfamily Pneumovirinae, Genus Pneumovirus 346 Members of the Subfamily Pneumovirinae, Genus Metapneumovirus 347 Unclassified Members of Family Paramyxoviridae 348 Chapter 18. Rhabdoviridae 350 Properties of Rhabdoviruses 350 Members of the Genus Lyssavirus 354 Members of the Genus Vesiculovirus 359 Members of the Genus Ephemerovirus 361 Rhabdoviruses Diseases of Fish: Genera Vesiculovirus and Novirhabdovirus 362 Chapter 19. Filoviridae 366 Properties of Filoviruses 366 Marburg and Ebola Hemorrhagic Fever Viruses 368 Chapter 20. Bornaviridae 372 Properties of Borna Disease Virus 372 Borna Disease Virus 373 Avian Bornavirus 375 Chapter 21. Orthomyxoviridae 376 Properties of Orthomyxoviruses 379 Members of the Genus Influenzavirus A 384 Members of the Genus Isavirus 392 Other Orthomyxoviruses 393 Chapter 22. Bunyaviridae 394 Properties of Bunyaviruses 395 Members of the Genus Orthobunyavirus 398 Members of the Genus Phlebovirus 399 Members of the Genus Nairovirus 403 Members of the Genus Hantavirus 404 Chapter 23. Arenaviridae 408 Properties of Arenaviruses 408 Old World Arenaviruses 411 New World Arenaviruses 414 Chapter 24. Coronaviridae 416 Properties of Coronaviruses 417 Members of the Genus Coronavirus 422 Members of the Genus Torovirus 435 Chapter 25. Arteriviridae and Roniviridae 438 Properties of Arteriviruses and Roniviruses 438 Members of the Family Arteriviridae, Genus Arterivirus 441 Members of the Family RonivirIdae, Genus Okavirus 446 Unclassified Nidoviruses of Fish 446 Chapter 26. Picornaviridae 448 Properties of Picornaviruses 449 Members of the Genus Aphthovirus 454 Members of the Genus Enterovirus 458 Members of the Genus Teschovirus 460 Members of the Genus Cardiovirus 461 Members of the Genus Erbovirus 462 Members of the Genus Kobuvirus 462 Unclassified Picornaviruses 462 Chapter 27. Caliciviridae 466 Properties of Caliciviruses 466 Members of the Genus Vesivirus 469 Members of the Genus Lagovirus 472 Members of the Genus Norovirus 473 Other Calicivirus infections of Animals 473 Chapter 28. Astroviridae 474 Properties of Astroviruses 474 Turkey Astrovirus 476 Avian Nephritis Virus 477 Other Astroviruses 477 Chapter 29. Togaviridae 478 Properties of Togaviruses 479 Members of the Genus Alphavirus Equine Alphaviruses 481 Other Zoonotic AlphaViruses 486 Salmonid Alphaviruses 486 Chapter 30. Flaviviridae 490 Properties of Flaviviruses 492 Members of the Genus Flavivirus: Mosquito-Borne Flaviviruses 494 Members of the Genus Flavivirus: Tick-Borne Encephalitis Viruses 498 Members of the Genus Pestivirus 498 Chapter 31. Other Viruses: Hepeviruses, Hepadnaviridae, Deltaviruses, Anelloviruses, and Unclassified Viruses 506 Members of the Genus Hepevirus 506 Members of the Family Hepadnaviridae 508 Members of the Floating Genus Deltavirus 509 Members of the Floating Genus Anellovirus 510 Unclassified Arboviruses 510 Chapter 32. Prions: Agents of Transmissible Spongiform Encephalopathies 512 Properties of Prions 513 Scrapie 515 Sporadic Spongiform Encephalopathy of Sheep and Goats 517 Bovine Spongiform Encephalopathy 517 Atypical Bovine Spongiform Encephalopathy 519 Transmissible Mink Encephalopathy 519 Chronic Wasting Disease of Deer and Elk 519 Human Prion Diseases 519 Index 522 A 522 B 522 C 523 D 524 E 524 F 525 G 525 H 526 I 526 J 526 K 527 L 527 M 527 N 527 O 527 P 527 Q 528 R 528 S 529 T 530 U 530 V 530 W 530 X 530 Y 530 Fenner's Veterinary, Virology 4e, is the long awaited new edition of Veterinary Virology, 3e, which was published in 1999. Fully revised and updated by the new author team, part I presents the fundamental principles of virology related to animal infection and disease, and part II addresses the clinical features, pathogenesis, diagnosis, epidemiology and prevention of individual diseases.

New to this Edition
* New author team - one main author to ensure that the book reads like an authored book but with the benefit of using experts to contribute to specific topics
* Text has been refocused - part I has been condensed and where appropriate incorporated into part II to make it more user friendly
* The number of figures have been increased and are now in full color

Key Features and Benefits

· Fully revised and updated to include the latest information in the field of veterinary virology

· Beautifully illustrated color figures throughout

· Organized and current information provided by an expert team of authors