Female contraception : update and trends ; with 90 tab. ; [2. international symposium, held in Heidelberg on June 13-16, 1987

Contraceptives have always provided ground for controversy. This book describes and discusses latest findings concerning the advantages as well as hazard and risk factors of contraception. The clinical impact of oral contraceptives on metabolism is particularly highlighted. In addition, behavioral methods, intrauterine devices, implants and modern approaches in animal and clinical research in the field of immunization against pregnancy are considered. Last, but not least, the book summarizes the complex ethical, religious and political aspects of family planning and contraception. Front Matter....Pages I-XII Front Matter....Pages 1-1 Reproductive Behavior and Family Planning....Pages 3-11 Trends in Contraception and Contraceptive Research....Pages 12-17 Front Matter....Pages 19-19 Analysis of Oral Contraceptive Risks....Pages 21-55 Effects of Oral Contraception on Blood Clotting....Pages 56-59 Effect of Oral Contraceptives on Carbohydrate Metabolism in Healthy Women....Pages 60-63 Oral Contraceptives and Lipid Metabolism....Pages 64-90 Oral Contraceptives and Lipid Metabolism: Interim Analysis of the PROCAM Trial....Pages 91-96 Oral Contraception and Ovarian Function....Pages 97-105 Front Matter....Pages 107-107 Trends in Hormonal Contraception....Pages 109-121 Clinical Pharmacology of Gestagens....Pages 122-128 Development of Progestogens....Pages 129-140 Review of the Preclinical Pharmacology and Clinical Studies of the Norgestimate-containing Oral Contraceptive, Cilest....Pages 141-146 Gestoden: An Innovative Progestogen....Pages 147-155 Desogestrel: Review of Pharmacology and Clinical Trials....Pages 156-163 Front Matter....Pages 165-165 Progesterone and Progestins Modulate Hypothalamic and Pituitary β -Endorphin....Pages 167-172 Contraceptive Potential of GnRH Antagonists....Pages 173-183 Desensitization of Pituitary Cells by Gonadotropin-Releasing Hormone in Vitro....Pages 184-191 Potency of Contraceptive Progestins to Inhibit Luteinizing Hormone Secretion in Vitro....Pages 192-205 Front Matter....Pages 207-207 Long-Acting Injectable Steroidal Contraception Utilizing Norethindrone Microspheres....Pages 209-220 Monthly Injectable Contraception with Norethisterone Enanthate plus Estradiol Valerate....Pages 221-226 Front Matter....Pages 207-207 Evaluation of the Norplant Subdermal Implant Contraceptive System — China....Pages 227-228 Front Matter....Pages 229-229 The Sympto-thermal Method....Pages 231-238 Temperature Computers....Pages 239-247 Lactational Anovulation in Monkeys: Prolactin Secretion and Ovarian Function....Pages 248-255 Front Matter....Pages 257-257 New Approaches in Vaginal Contraception....Pages 259-276 New Techniques of Female Sterilisation....Pages 277-279 Recent Experience with the Cervical Cap in the United States....Pages 280-285 Aryl 4-Guanidinobenzoates: Potential Vaginal Contraceptives....Pages 286-292 Front Matter....Pages 293-293 Intrauterine Devices: Efficacy and Side Effects....Pages 295-311 Hazards of IUDs and Their Prevention....Pages 312-324 The Endometrium and the IUD....Pages 325-335 Clinical Results of a New Contraceptive Intra-uterine Device: Ombrelle 250....Pages 336-341 Front Matter....Pages 343-343 Immunological Aspects of Fertility Regulation....Pages 345-350 Application of New Concepts in Cell-Mediated Immunity to the Development of Effective Antifertility Vaccines....Pages 351-355 Sperm Antigens and Antibodies....Pages 356-367 Front Matter....Pages 369-369 Post-coital Interception....Pages 371-380 Endometrial and Myometrial Effects of Progesterone Antagonists in Pregnant Guinea Pigs....Pages 381-381 Front Matter....Pages 383-383 The Role of Public Sector Agencies in Contraceptive Research and Development....Pages 385-392 Jewish Law and Contraceptive Practice....Pages 393-397 Front Matter....Pages 399-399 Epidemiology and Sexually Transmitted Diseases....Pages 401-419 Front Matter....Pages 421-421 The World Health Organization Special Programme of Research, Development and Research Training on Human Reproduction: The Past 15 Years and the Next Decade....Pages 423-439 Back Matter....Pages 441-443