Experimental design and model choice : the planning and analysis of experiments with continuous or categorical response : with 28 figures

This Book Is A Translation Of The Up-dated Version Of My German Textbook That Was Written Parallel To My Lecture Design Of Experiments Which I Held At The University Of Munich. It Was Often Called To My Attention By Statisticians In The Pharmaceutical In­ Dustry, That There Is A Need For A Summarizing And Standardized Representation Of The Design And Analysis Of Experiments, That Includes The Different Aspects Of Classical Theory For Continuous Response And Of Modern Procedures For Categori­ Cal And Especially Correlated Response, As Well As More Complex Designs, As For Example Cross-over And Repeated Measures. My Staff And Graduate Students Played An Essential Part In The Preparation Of The Manuscript. They Wrote The Text In Well-tried Precision (andreas Fie­ Ger), Worked Out Examples (andreas Fieger, Christian Kastner), And Prepared Several Sections In This Book (ulrike Feldmeier, Sabina Illi, Elke Ortmann, An­ Drea Schopp, Irmgard Strehler, Christian Kastner, Oliver Loch). I Am Appreciative Of The Efforts Of Those Who Assisted In The Preparation Of The English Version. In Particular, I Would Like To Thank Sabina Illi And Oliver Loch, As Well As V.k. Srivastava (university Of Lucknow, India) For Their Careful Reading Of The English Version And Invaluable Suggestions. Contents: Introduction -- Comparison Of Two Samples -- The Linear Regression Model -- Single-factor Experiments With Fixed And Random Effects -- More Restrictive Designs -- Multifactor Experiments -- Repeated Measures Model -- Cross-over Design -- Statistical Analysis Of Incomplete Data -- Models For Categorical Response. By Helge Toutenburg. Front Matter....Pages I-XII Introduction....Pages 1-21 Comparison of Two Samples....Pages 23-44 The Linear Regression Model....Pages 45-93 Single-Factor Experiments with Fixed and Random Effects....Pages 95-143 More Restrictive Designs....Pages 145-165 Multifactor Experiments....Pages 167-216 Repeated Measures Model....Pages 217-262 Cross-Over Design....Pages 263-306 Statistical Analysis of Incomplete Data....Pages 307-334 Models for Categorical Response....Pages 335-401 Back Matter....Pages 403-465 This textbook gives a representation of the design and analysis of experiments, that comprises the aspects of classical theory for continuous response and of modern procedures for categorical response, and especially for correlated categorical response. Complex designs, as for example, cross-over and repeated measures, are included. Thus, it is an important book for statisticians in the pharmaceutical industry as well as for clinical research in medicine and dentistry.