Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care

In anesthesiology, pain medicine, and critical care, practitioners at all levels need help to stay current with the continually evolving drug knowledge-base, and trainees need tools to prepare for in-training and board exams that increasingly test their knowledge of pharmacology. This practical book is aimed at both readerships. It features a unique and practical chapter on the United States Food and Drug Administration (FDA) "black box" warnings that describe what safety precautions should be taken with commonly used drugs. The editors and contributors are pharmacology experts representing a cross-section of clinical specialties and institutions in the United States and include pharmacologists, pharmacists, as well as physicians. -- [Résumé de l'éditeur] In anesthesiology, pain medicine, and critical care, practitioners at all levels need help to stay current with the continually evolving drug knowledge-base, and trainees need tools to prepare for in-training and board exams that increasingly test their knowledge of pharmacology.℗lThis practical book is aimed at both readerships. It features a unique and practical chapter on the United States Food and Drug Administration (FDA) ĺlblack boxĺl warnings that describe what safety precautions should be taken with commonly used drugs. The editors and contributors are pharmacology experts representing a cross-section of clinical specialties and institutions in the United States and include pharmacologists, pharmacists, as well as physicians. Part I. Basic Pharmacologic Principles -- 1. Pharmacokinetics and Pharmacodynamics of Anesthetics -- 2. A Review of Mechanisms of Inhalational Anesthetic Agents -- 3. Pharmacokinetics, pharmacodynamics and physical properties of Inhalational agents -- 4. Principles of Total Intravenous Anesthesia -- 5. Perioperative Considerations in Pharmacology -- Part II. Drug Classes -- 6. Anesthetic Induction Agents -- 7. Analgesics: Opiate agonists, mixed agonist/antagonists and antagonists for acute pain management -- 8. Analgesics: Opioids for chronic pain management and surgical considerations -- 9. Nonopioid Analgesic and Adjunct Drugs -- 10. Benzodiazepines and muscle relaxants -- 11. Pharmacology of Local Anesthetics -- 12. Neuromuscular Blockers -- 13. Reversal agents -- 14. Drugs acting on the autonomic nervous system -- 15. Antihypertensives, diuretics and antidysrhythmics -- 16. Peripheral vasodilators -- 17. Nitric oxide and Pulmonary Vasodilators -- 18. Asthma and COPD agents --^ 19. Hormones, Part 1: Thyroid and Corticosteroid Hormones -- 20. Hormones, Part 2: Insulin and Other glucose controlling Medications -- 21. Antacids, Gastrointestinal Prokinetics, And Proton Pump Inhibitors -- 22. Histamine modulators -- 23. Central Nervous System Stimulants -- 24. Anticoagulant drugs -- 25. Hemostatic Agents -- 26. BLOOD, BLOOD PRODUCTS, AND SUBSTITUTES -- 27. Antipyretics: Acetaminophen, Arachidonic Acid Agents, Cox1 And Cox2 Inhibitors -- 28. Antiemetic Agents -- 29. Antiepileptics agents -- 30. Neuropharmacologic agents for neurologic conditions -- 31. Chemotherapeutic Agents -- 32. Antimicrobial Agents -- 33. Herbals medications and vitamin supplements -- 34. Minerals and electrolytes -- 35. Disinfection agents and antiseptics -- 36. Psychopharmacologic agents and psychiatric drug considerations -- 37. Cocaine, Methamphetamine, MDMA and Heroin -- Part III. Clinical Subspecialties -- 38. Cardiac surgery -- 39. The Intensive Care Unit --^ 40. Enteral and parenteral nutrition -- 41. Obstetrics -- 42. Pediatrics -- 43. Neurologic Surgery -- 44. Liver disease and liver transplantation -- Part IV. Special Topics -- 45. Black Box FDA warnings and legal implications -- 46. Drug-Induced QT Prolongation -- 47. Drugs and Cancer Propagation -- 48. Lipid Lowering Agents -- 49. Serotonin Syndrome -- Part V. New Vistas in Pharmacology -- 50. Novel Psychoactive Substances: synthetic cathinones and cannabinoid receptor agonists -- 51. New Vistas in Anesthetics, IV Induction Agents -- 52. New Vistas In Neuromuscular Blockers -- 53. Patient-Controlled Analgesia: The Importance of Effector Site Pharmacokinetics -- 54. Understanding anesthesia-induced memory loss -- 55. Novel Targets of Current Analgesic Drug Development. Alan David Kaye, Adam M. Kaye, Richard D. Urman, editors. Includes bibliographical references and index. Mode of access: World Wide Web. Front Matter....Pages i-xxii Front Matter....Pages 1-1 Pharmacokinetics and Pharmacodynamics of Anesthetics....Pages 3-47 A Review of Mechanisms of Inhalational Anesthetic Agents....Pages 49-60 Pharmacokinetics, Pharmacodynamics, and Physical Properties of Inhalational Agents....Pages 61-71 Principles of Total Intravenous Anesthesia....Pages 73-86 Perioperative Considerations in Pharmacology....Pages 87-99 Front Matter....Pages 101-101 Anesthetic Induction Agents....Pages 103-111 Analgesics: Opiate Agonists, Mixed Agonists/Antagonists, and Antagonists for Acute Pain Management....Pages 113-123 Analgesics: Opioids for Chronic Pain Management and Surgical Considerations....Pages 125-145 Nonopioid Analgesic and Adjunct Drugs....Pages 147-165 Benzodiazepines and Muscle Relaxants....Pages 167-178 Pharmacology of Local Anesthetics....Pages 179-194 Neuromuscular Blockers....Pages 195-204 Reversal Agents....Pages 205-218 Drugs Acting on the Autonomic Nervous System....Pages 219-233 Antihypertensives, Diuretics, and Antidysrhythmics....Pages 235-256 Peripheral Vasodilators....Pages 257-273 Nitric Oxide and Pulmonary Vasodilators....Pages 275-293 Asthma and COPD Agents....Pages 295-312 Hormones, Part 1: Thyroid and Corticosteroid Hormones....Pages 313-325 Hormones Part 2: Insulin and Other Glucose-Controlling Medications....Pages 327-343 Front Matter....Pages 101-101 Antacids, Gastrointestinal Prokinetics, and Proton Pump Inhibitors....Pages 345-363 Histamine Modulators....Pages 365-379 Central Nervous System Stimulants....Pages 381-396 Anticoagulant Drugs....Pages 397-413 Hemostatic Agents....Pages 415-420 Blood, Blood Products, and Substitutes....Pages 421-432 Antipyretics: Acetaminophen, Arachidonic Acid Agents, and COX1 and COX2 Inhibitors....Pages 433-443 Antiemetic Agents....Pages 445-451 Antiepileptic Agents....Pages 453-483 Neuropharmacologic Agents for Neurologic Conditions....Pages 485-502 Chemotherapeutic Agents....Pages 503-523 Antimicrobial Agents....Pages 525-547 Herbal Medications and Vitamin Supplements....Pages 549-562 Minerals and Electrolytes....Pages 563-572 Disinfection Agents and Antiseptics....Pages 573-580 Psychopharmacologic Agents and Psychiatric Drug Considerations....Pages 581-594 Cocaine, Methamphetamine, MDMA, and Heroin....Pages 595-605 Front Matter....Pages 607-607 Cardiac Surgery....Pages 609-643 The Intensive Care Unit....Pages 645-659 Enteral and Parenteral Nutrition....Pages 661-675 Front Matter....Pages 607-607 Obstetrics....Pages 677-696 Pediatrics....Pages 697-705 Neurologic Surgery....Pages 707-717 Liver Disease and Liver Transplantation....Pages 719-737 Front Matter....Pages 739-739 Black Box FDA Warnings and Legal Implications....Pages 741-751 Drug-Induced QT Prolongation....Pages 753-766 Drugs and Cancer Propagation....Pages 767-781 Lipid-Lowering Agents....Pages 783-796 Serotonin Syndrome....Pages 797-807 Front Matter....Pages 809-809 Novel Psychoactive Substances: Synthetic Cathinones and Cannabinoid Receptor Agonists....Pages 811-818 New Vistas in Anesthetics, IV Induction Agents....Pages 819-826 New Vistas in Neuromuscular Blockers....Pages 827-835 Patient-Controlled Analgesia: The Importance of Effector Site Pharmacokinetics....Pages 837-846 Understanding Anesthesia-Induced Memory Loss....Pages 847-858 Novel Targets of Current Analgesic Drug Development....Pages 859-873 Back Matter....Pages 875-904 In anesthesiology, pain medicine, and critical care, practitioners at all levels need help to stay current with the continually evolving drug knowledge-base, and trainees need tools to prepare for in-training and board exams that increasingly test their knowledge of pharmacology. This practical book is aimed at both readerships. It features a unique and practical chapter on the United States Food and Drug Administration (FDA) "black box" warnings that describe what safety precautions should be taken with commonly used drugs. The editors and contributors are pharmacology experts representing a cross-section of clinical specialties and institutions in the United States and include pharmacologists, pharmacists, as well as physicians. -- [Résumé de l'éditeur] In anesthesiology, pain medicine, and critical care, practitioners at all levels need help to stay current with the continually evolving drug knowledge-base, and trainees need tools to prepare for in-training and board exams that increasingly test their knowledge of pharmacology. This practical book is aimed at both readerships. It features a unique and practical chapter on the United States Food and Drug Administration (FDA) ĺlblack boxĺl warnings that describe what safety precautions should be taken with commonly used drugs. The editors and contributors are pharmacology experts representing a cross-section of clinical specialties and institutions in the United States and include pharmacologists, pharmacists, as well as physicians