Epigenetic Contributions in Autoimmune Disease (Advances in Experimental Medicine and Biology, Vol. 711)

This volume focuses on the relevance of epigenetic mechanisms in autoimmune disease. It provides new directions for future research in autoimmune disease. An Introduction To Epigenetics / Esteban Ballestar -- Chromatin Mechanisms Regulating Gene Expression In Health And Disease / Constanze Bonifer And Peter N. Cockerill -- Epigenetic Control Of Lymphocyte Differentiation / Eduardo Lopez-granados -- Epigenetic Control In Immune Function / Peter J. Van Den Elsen, Marja C.j.a. Van Eggermond, And Rutger J. Wierda -- Dna Methylation And B-cell Autoreactivity / Soizic Garaud, Pierre Youinou, And Yves Renaudineau -- Environmental Agents And Autoimmune Diseases / Frederick W. Miller -- Epigenetic Dysregulation Of Epstein-barr Virus Latency And Development Of Autoimmune Disease / Hans Helmut Niller ... [et Al.] -- Does Genomic Imprinting Play A Role In Autoimmunity? / Cristina Camprubø And David Monk -- A New Epigenetic Challenge : Systemic Lupus Erythematosus / Biola M. Javierre And Bruce C. Richardson. Epigenetic Deregulation In Rheumatoid Arthritis / Emmanuel Karouzakis ... [et Al.] -- Prospects For Epigenetic Compounds In The Treatment Of Autoimmune Disease / Nadine Chapman-rothe And Robert Brown -- Profiling Epigenetic Alterations In Disease / Josø Ignacio Martøn-subero And Manel Esteller. Edited By Esteban Ballestar. Includes Bibliographical References And Index. Front Matter....Pages i-xvi An Introduction to Epigenetics....Pages 1-11 Chromatin Mechanisms Regulating Gene Expression in Health and Disease....Pages 12-25 Epigenetic Control of Lymphocyte Differentiation....Pages 26-35 Epigenetic Control in Immune Function....Pages 36-49 DNA Methylation and B-Cell Autoreactivity....Pages 50-60 Environmental Agents and Autoimmune Diseases....Pages 61-81 Epigenetic Dysregulation of Epstein-Barr Virus Latency and Development of Autoimmune Disease....Pages 82-102 Does Genomic Imprinting Play a Role in Autoimmunity?....Pages 103-116 A New Epigenetic Challenge: Systemic Lupus Erythematosus....Pages 117-136 Epigenetic Deregulation in Rheumatoid Arthritis....Pages 137-149 Prospects for Epigenetic Compounds in the Treatment of Autoimmune Disease....Pages 150-161 Profiling Epigenetic Alterations in Disease....Pages 162-177 Back Matter....Pages 179-182