Enzyme Regulation and Mechanism of Action : Proceedings of the FEBS Special Meeting on Enzymes, Cavtat, Dubrovnik, 1979

Enzyme Regulation and Mechanism of Action contains the proceedings of the Federation of European Biochemical Societies'Special Meeting on Enzymes held in Dubrovnik, Croatia in 1979. The meeting provided a forum for reviewing advances in understanding the regulation and mechanism of action of enzymes. The discussions are organized around three themes: regulation of enzyme activity; the role of enzymes in the synthesis of nucleic acids and proteins; and proteolytic enzymes. Comprised of 33 chapters, this volume begins with an analysis of partial amino acid sequence of rabbit liver fructose 1,6-bisphophatase and sites of cleavage by proteinases. The reader is then introduced to physiological inactivation of enzymes in yeasts; structure and functions of protein kinases; and control points in the citric acid cycle. Subsequent chapters focus on ligand binding properties and subunit interactions in yeast alcohol dehydrogenase; the role of water in the acceleration of an enzymatic reaction; DNA polymerases of human normal and leukemic cells; and the phylogenetic and developmental aspects of gastric proteinases and their zymogens. This book is intended for enzymologists. Content: TRENDS IN ENZYMOLOGY, Page ii Front Matter, Page iii Copyright, Page iv PREFACE, Page ix, P. Mildner, B. Ries LIST OF CONTRIBUTORS, Pages xi-xviii PARTIAL AMINO ACID SEQUENCE OF RABBIT LIVER FRUCTOSE 1,6-BISPHOSPHATASE (Fru-P2ase, EC 3.1.3.11) AND SITES OF CLEAVAGE BY PROTEINASES, Pages 3-14, B.L. Horecker, J.S. MacGregor, V.N. Singh, O. Tsolas, S.C. Sun, O. Crivellaro, S. Pontremoli PHYSIOLOGICAL INACTIVATION OF ENZYMES IN YEASTS, Pages 15-22, C. Gancedo, S. Funayama, J.M. Gancedo STRUCTURAL REQUIREMENTS OF A RAT LIVER PROTEINKINASE DISPLAYING A SPECIFICITY SIMILAR TO THAT OF THE MAMMARY GLAND CASEINKINASE(S), Pages 23-33, F. Meggio, A. Donella Deana, L.A. Pinna STRUCTURE AND FUNCTIONS OF PROTEIN KINASES, Pages 35-46, E.S. Severin, S.N. Kochetkov, T.B. Bulargina, Kh. A. Ulmasov, I.A. Grivennikov, I.N. Trakht, S.F. Barbashov, L.P. Sashchenko, M.V. Nesterova STRUCTURE, FUNCTION AND REGULATION OF THE MAMMALIAN PYRUVATE DEHYDROGENASE COMPLEX, Pages 47-56, L.J. Reed, F.H. Pettit, S.J. Yeaman, W.M. Teague, D.M. Bleile ROLE OF ENZYME CATALYZED COVALENT MODIFICATIONS IN REGULATION OF GLUTAMINE SYNTHETASE, Pages 57-68, E.R. Stadtman, P.B. Chock, S.G. Rhee CONTROL POINTS IN THE CITRIC ACID CYCLE, Pages 69-82, J.H. Ottaway, C.L. McMinn ACID PHOSPHATASE, A GLYCOPROTEIN OF THE YEAST CELL WALL, Pages 83-92, P. Mildner, S. Barbarić, B. Kozulić, B. Ries LIGAND BINDING PROPERTIES AND SUBUNIT INTERACTIONS IN YEAST ALCOHOL DEHYDROGENASE, Pages 93-102, V. Leskovac PROBING OF ENZYME MICROENVIRONMENT BY FLUORESCEIN DERIVATIVES, Pages 103-112, N.G. Oikonomakos, T.G. Sotiroudis, A.E. Evangelopoulos ON THE ROLE OF WATER IN THE ACCELERATION OF AN ENZYMATIC REACTION, Pages 113-122, M.R. Pavlič RESTRICTION NUCLEASES IN THE ANALYSIS OF BOVINE 1.706 SATELLITE DNA, Pages 125-134, R.E. Streeck, M. Pech, H.G. Zachau ENZYMATIC SYNTHESIS OF SITE-SPECIFIC MUTATIONS IN AN ESSENTIAL GENE OF BACTERIOPHAGE fX174, Pages 135-144, R.W. Chambers, O.S. Bhanot, M. Zafri Humayun DNA POLYMERASES OF HUMAN NORMAL AND LEUKEMIC CELLS, Pages 145-158, M.G. Sarngadharan, R.C. Gallo COMPARATIVE STUDIES OF STRUCTURE AND FUNCTION OF DNA-DEPENDENT RNA POLYMERASES FROM EUBACTERIA AND ARCHAEBACTERIA, Pages 159-178, W. Zillig, K.O. Stetter, W. Schulz, D. Janekovic IN VITRO TRANSCRIPTION OF CLONED EUKARYOTIC tRNA GENES, Pages 179-188, O. Schmidt, B. Hovemann, S. Silverman, H. Yamada, J. Mao, D. Söll CRYSTALLOGRAPHIC STUDIES OF TYROSYL tRNA SYNTHETASE, Pages 189-198, D.M. Blow, J.R. Rubin MOLECULAR ENZYMOLOGY OF TRYPTOPHANYL-tRNA SYNTHETASE FROM BEEF PANCREAS, Pages 199-210, L.L. Kisselev, G.K. Kovaleva, O.O. Favorova, V.S. Scheinker, S.F. Beresten AMINOACYL-tRNA SYNTHETASES: INTERACTIONS WITH THEIR LIGANDS, Pages 211-221, J.P. Ebel, P. Remy, M. Baltzinger, R. Ehrlich, J.F. Lefevre, M. Renaud, F. Fasiolo, G. Keith, O. Favorova, S. Vassilenko, R. Giege, A. Dietrich, D. Kern, D. Moras, J.C. Thierry, B. Jacrot, G. Zaccai PROOFREADING PROCESSES IN PROTEIN BIOSYNTHESIS - ON THE MECHANISM OF AMINOACYLATION OF tRNA, Pages 223-232, F. Cramer POLYNUCLEOTIDE PHOSPHORYLASE AS A PROBE FOR THE REGULATORY FUNCTION OF THE 3′-OH REGION OF mRNA AND VIRAL RNA IN TRANSLATION, Pages 233-243, U.Z. Littauer, H. Soreq, P. Cornelis CORTISOL MEDIATED CONTROL AT THE TRANSLATION LEVEL IN ANABOLIC TARGET LIVER CELLS. I. MODULATION OF TRANSLATION AND RIBOSOMAL PROTEINS PHOSPHORYLATION, Pages 245-257, D. Kanazir, D. Stefanović, R. Metlaš, S. Popić, M. Katan, D. Trajković, N. Ribar-Stepić, R. Djordjević COORDINACY IN THE INDUCTION OF ACID GLYCOSIDASES BY TESTOSTERONE IN MICE, Pages 259-268, S.L. Petrović, J.S. Borota, M.B. Novaković, D.V. Marinković GASTRIC PROTEINASES AND THEIR ZYMOGENS. PHYLOGENETIC AND DEVELOPMENTAL ASPECTS, Pages 271-280, B. Foltmann, N.H. Axelsen THE ACTIVE SITE OF ACID PROTEINASES, Pages 281-288, T.L. Blundell, H.B. Jones, G. Khan, G. Taylor, B.T. Sewell, L.H. Pearl, S.P. Wood STRUCTURE AND FUNCTION OF CATHEPSIN D, Pages 289-306, J.S. Huang, S.S. Huang, J. Tang THIOL PROTEINASES OF HUMAN LYSOSOMES, Pages 307-315, A.J. Barrett CARBOXYL AND THIOL INTRACELLULAR PROTEINASES, Pages 317-330, V. Turk, I. Kregar, F. Gubenšek, T. Popovič, P. Lenikar, T. Lah INTRACELLULAR SERINE PROTEINASES OF BACTERIA - ISOLATION, CHEMISTRY, EVOLUTIONARY ASPECTS, Pages 331-337, V.M. Stepanov PROTEINASES AND ENDOGENOUS PROTEINASE INHIBITORS IN YEAST, Pages 339-349, M. Müller, H. Holzer THE STRUCTURE-FUNCTION RELATIONSHIPS OF COLLAGENOLYTIC ENZYMES, Pages 351-362, B. Keil INTRACELLULAR NEUTRAL PROTEINASES AND THEIR INHIBITORS, Pages 363-375, M. Kopitar, J. Brzin, J. Babnik, V. Turk, A. Suhar CHARACTERISTICS OF THE UPTAKE AND DEGRADATION OF YEAST INVERTASE IN RAT TISSUES, Pages 377-390, Harold L. Segal, Herman M. Madnick, Allan C. Parks AUTHOR INDEX, Pages 391-404 SUBJECT INDEX, Pages 405-410