Environmental Effects on Molecular Structure and Properties : Proceedings of the Eighth Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, April 7th–11th 1975

The holding of the 8th Jerusalem Symposium was saddened by the sudden death of Professor Ernst D. Bergmann at the very eve of this meeting. With him disappeared one of the leading world scientists in the field of physical chemistry and biochemistry. His innumerable friends and admirers over the whole world mourn him profoundly. All those who knew him personally and among them the participants in the previous Jerusalem Symposia will remember for ever the exceptional qualities of the scientist and the unusual human warmth of the man. With Ernst D. Bergmann the state of Israel lost one of the founders of its Science and one of its most brilliant and renowned representatives. The spirit which he suc­ ceeded to inoculate into his numerous disciples and pupils will, however, continue to perpetuate his name and his work. The Jerusalem Symposia will continue as a living testimony to his brilliant inspiration. Before dying, Professor Bergmann has prepared a few opening remarks for the 8th Jerusalem Symposium. They are reproduced here. BERNARD PULLMAN OPENING WORDS Prepared by the Late Professor Ernst David Bergmann It gives me great pleasure to welcome you all on behalf of the President and the Rector of the Hebrew University which is co-sponsoring this meeting, and of the President and Council of the Israel Academy of Sciences and Humanities which for the eighth time has put its premises at our disposal. Front Matter....Pages I-XI Molecular Orbital ‘Supermolecule’ Approach to the Solvation Problem....Pages 1-15 On the Development of Solvent Effect Models: Method Development and Initial Applications....Pages 17-29 Electrostatic Properties of Proteins: Role of the Aqueous Solution in Determining Protein Secondary and Tertiary Structure....Pages 31-39 Approaches to the Problem of Solvation Calculations in Polar and Charged Molecules....Pages 41-53 Quantum-Mechanical Studies on the Effect of Water on the Conformation of Two Biologically Important Zwitterionic Systems: Polar Head of Phospholipids and Gaba....Pages 55-80 Solvent Effects on Acidity and Basicity from Gas Phase Ion Equilibria Measurements....Pages 81-94 Conformation of Peptides in Water....Pages 95-108 Theoretical Studies on the Conformation of Peptides in Solution....Pages 109-133 Molecular Environmental Effects on the Puckering of the Proline Ring....Pages 135-164 Molecular Design: Theoretical and Solution Studies on Copper(II) Complex of Glycylglycyl-L-Histidine-N-Methyl Amide, A Peptide Designed to Mimic The Copper(II)-Transport Site of Human Albumin....Pages 165-178 Molecular Complexes and Chemical Behaviour: Competitive Preferential Solvation Theory and its Applications....Pages 179-203 Calorimetric Studies of Hydrophobic Interactions in Aqueous Solution....Pages 205-213 Changes in the Adherence of Hydrophobic Groups, and Corresponding Alterations in Molecular Conformation of Biopolymers, with Changes in Interfacial Tension of their Aqueous Solutions....Pages 215-228 Solute-Solute and Solute-Solvent Interactions: NMR Studies....Pages 229-238 Theoretical Study of the Solvent Effect on Ionization and Partition Behavior in Related Opiate Narcotics: Hydromorphone and Oxymorphone....Pages 239-258 Solvent Effect and Aromatic Compounds: Magneto-Optic Properties....Pages 259-264 α -Cyclodextrin Inclusion Complexes: Mechanism of Adduct Formation and Intermolecular Interactions....Pages 265-305 Correlation of Chemical Reactivity in the Solid State with Crystal Structure....Pages 307-327 The Effects of the Crystal Lattice on the Electronic Distribution of the Nitrite Ion in the Ferroelectric Phase of Na 2 NO 2 ....Pages 329-342 Intra- and Intermolecular Interactions in Azanucleosides....Pages 343-354 Chromophore Protein Interactions in Visual Pigments and their Analogs....Pages 355-362 Effect of the Counter Anion on the Oxidation of N-Benzyl-1,4-Dihydronicotinamide....Pages 363-369 Influence of Cations on Secondary Structures of Macromolecules and Membranes - IR Investigations....Pages 371-388 Hemoglobin Interaction in Sickle Cell Fibers: Theoretical Approaches to the Molecular Contacts....Pages 389-407 Application of Competitive Labelling to the Study of the Effect of Environment on the Chemical Properties of Groups in Proteins: Environmental Effects on Histidine Residues....Pages 409-417 The Stability of Bovine Pancreatic Ribonuclease in Glycerol and Glycerol-Cosolvents....Pages 419-435 A New Empirical Intermolecular Potential Energy Function for Hydrogen Bonding: Application to the Gas Phase and Solid State of Carboxylic Acids and Alcohols....Pages 437-457 Use of Energy Calculations to Refine and Understand Structure and Function of Proteins....Pages 459-483 Coenzyme Apoenzyme Interactions: Studies on the Binding of Thiamine Diphosphate to Apotransketolase From Baker’s Yeast....Pages 485-503 Electron Transport in Cytochrome C....Pages 505-515 The Effect of Temperature on the Structure of Lysozyme in Solution....Pages 517-527 On the Anesthetic Potency of Fluorocarbons, their Ionization Potentials, and their Dissociative Effect on Hydrogen Bonds....Pages 529-533 A Preliminary Refinement of Yeast t RNA Phe at 3Å Resolution....Pages 535-545 The Modification by Biliproteins of Intensity and Direction of Electron Flow Across Chlorophyll-Containing Membranes....Pages 547-560 Environmental Effects on Processes of Excited Molecules-External Spinorbit Coupling Effects on Photochemical Reactions of Bianthrone-Like Molecules....Pages 561-571 Ground-State Versus Excited-State Polarity of Triafulvenes: A Study of Solvent Effects on Molecular Electronic Spectra[1]....Pages 573-583 Back Matter....Pages 585-588 Proceedings of the Eighth Jerusalem Symposium on Quantum Chemistry and Biochemistry held in Jerusalem, Israel, April 7-11, 1975