Endocrinology of the Heart in Health and Disease : Integrated, Cellular, and Molecular Endocrinology of the Heart

__Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart__ covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. * Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease * Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically * Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented.

The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds.

The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology.

• Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease
• Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically
• Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Content: Front-matter,Copyright,Dedication,List of Contributors,Foreword,Preface,AcknowledgmentsEntitled to full textPart I: The Heart as an Endocrine OrganChapter 1 - Cardiac Natriuretic Peptides, Pages 3-39 Chapter 2 - Adrenomedullin, Pages 41-58 Chapter 3 - Endothelin-1 as a Cardiac-Derived Autocrine, Paracrine and Intracrine Factor in Heart Health and Disease, Pages 59-85 Chapter 4 - The Cardiokines: An Expanding Family of the Heart Secretome, Pages 87-114 Chapter 5 - Novel Small Peptide Hormones, Pages 115-135 Chapter 6 - Gut-Derived Hormones—Cardiac Effects of Ghrelin and Glucagon-Like Peptide-1, Pages 139-166 Chapter 7 - Fat Hormones, Adipokines, Pages 167-205 Chapter 8 - Neuronal Hormones and the Sympathetic/Parasympathetic Regulation of the Heart, Pages 207-227 Chapter 9 - Renin Angiotensin Aldosterone System and Heart Function, Pages 229-248 Chapter 10 - Nuclear Receptors and the Adaptive Response of the Heart, Pages 249-284 Chapter 11 - Adrenergic Receptors, Pages 285-315 Chapter 12 - Insulin Signaling in Cardiac Health and Disease*, Pages 317-346 Index, Pages 347-354 Edited By Jonathan C. Schisler, Charles H. Lang, Monte S. Willis. Includes Index. Mode Of Access: World Wide Web.