Embryo Implantation: Molecular, Cellular and Clinical Aspects (Serono Symposia USA)

This volume contains the proceedings of the International Symposium on Embryo Implantation: Molecular, Cellular and Clinical Aspects, held from October 3-6, 1997 in Newport Beach, California. Internationally recognized experts discuss the development and future of human in vitro fertilization and embryo implantation, the cellular aspects of implantation, hormonal regulation, molecular markers of receptivity, trophoblast factors, primate models and animal studies, and transcriptional regulation of maternal-fetal recognition. Front Matter....Pages i-xviii Front Matter....Pages 1-1 Implantation in the Human as Viewed by Canon Law, Civil Law, and Natural Reason....Pages 3-11 The Impact of Maternal Age and Ovarian Age on Implantation Efficiency....Pages 12-19 Front Matter....Pages 21-21 Vascular Invasion During Implantation and Placentation....Pages 23-38 Oxygen Regulates Human Cytotrophoblast Proliferation, Differentiation, and Invasion: Implications for Endovascular Invasion in Normal Pregnancy and Preeclampsia....Pages 39-53 Embryo—Maternal Interactions after Diapause in a Marsupial....Pages 54-66 Cellular Interactions and the Cysteine Proteinases in the Process of Mouse Implantation....Pages 67-79 Front Matter....Pages 81-81 Novel Steroid-Regulated Markers of Implantation....Pages 83-91 Molecular Signaling in Implantation....Pages 92-106 Identification of Progesterone-Regulated Genes in the Uterus....Pages 107-119 Front Matter....Pages 121-121 Mucins Provide a Barrier to Embryo Implantation....Pages 123-131 Potential Involvement of Trophinin, Bystin, and Tastin in Embryo Implantation....Pages 132-140 Osteopontin in Human Endometrium: A Role in Endometrial Receptivity and Embryo Implantation?....Pages 141-148 Front Matter....Pages 149-149 The Rabbit as a Model for Implantation: In Vivo and In Vitro Studies....Pages 151-160 Regulation of Trophoblast Endocrine Function: The Placenta Does Its Own Thing Transcriptionally....Pages 161-166 Transcription Factors Regulating the Differentiation of the Trophoblast Cell Lineage....Pages 167-181 Front Matter....Pages 183-183 Hormonal Regulation of Endometrial Gene Expression in the Rhesus Monkey....Pages 185-201 Embryo—Maternal Dialogue in the Baboon (Papio Anubis) ....Pages 202-209 Integrins and Uterine Receptivity....Pages 210-222 Keratinocyte Growth Factor in the Nonhuman Primate Endometrium: Regulation and Action....Pages 223-241 Molecular Lesions in Infertility....Pages 242-246 Front Matter....Pages 247-247 The Role of Abdominal B (AbdB) Hoxa Genes During Implantation....Pages 249-260 Possible Role of the Transcription Factor Oct-3/4 in Control of Human Chorionic Gonadotropin Expression....Pages 261-270 Molecular Mechanisms Regulating Uterine Decidualization and Implantation: Cell—Cell and Cell—Extracellular Matrix Interactions....Pages 271-286 Regulation of Hormone Receptor Gene Expression in Endometrium....Pages 287-298 Back Matter....Pages 299-310