Electrofluidodynamic Technologies (EFDTs) for Biomaterials and Medical Devices: Principles and Advances (Woodhead Publishing Series in Biomaterials)

__Electrofluidodynamic Technologies (EFDTs) for Biomaterials and Medical Devices: Principles and Advances__ focuses on the fundamentals of EFDTs - namely electrospinning, electrospraying and electrodynamic atomization - to develop active platforms made of synthetic or natural polymers for use in tissue engineering, restoration and therapeutic treatments. The first part of this book deals with main technological aspects of EFDTs, such as basic technologies and the role of process parameters. The second part addresses applications of EFDTs in biomedical fields, with chapters on their application in tissue engineering, molecular delivery and implantable devices. This book is a valuable resource for materials scientists, biomedical engineers and clinicians alike. * Presents a complete picture of Electrofluidodynamic technologies and their use in biomedicine * Provides a comprehensive, professional reference on the subject, covering materials processing, fabrication and the use of novel devices for tissue engineering and therapeutics * Focuses on technological advances, with an emphasis on studies and clinical trials Front Cover -- Electrofluidodynamic Technologies (EFDTs) for Biomaterials and Medical Devices -- Related titles -- Electrofluidodynamic Technologies (EFDTs) for Biomaterials and Medical Devices -- Copyright -- Contents -- List of contributors -- Preface -- 1 - Introduction to electrofluidodynamic techniques. Part I: process optimization -- 1.1 Introduction -- 1.2 Basic principles -- 1.2.1 Electrospinning -- 1.2.2 Electrospraying -- 1.3 Tailoring processes for customized applications -- 1.3.1 Electrodynamic atomization for cell delivery -- 1.3.2 Melt writing for 3D ordered scaffolds -- 1.4 Additive processes for molecular release -- 1.5 Future trends -- Acknowledgments -- References -- 2 - Introduction to electrofluidodynamic techniques. Part II: cell-to-cell/material interactions -- 2.1 Introduction -- 2.2 Cell-material interactions on electrofluidodynamic spun mats -- 2.2.1 Morphological surface effects of EFDT spun membrane -- 2.2.2 Biochemical cues on cell/tissue response of EFDT spun membrane -- 2.3 Cell electrospinning -- 2.4 Animal models for evaluation of electrofluidodynamic material interactions -- 2.5 Conclusions -- Acknowledgments -- References -- 3 - Electrofluidodynamic technologies for biomaterials and medical devices: melt electrospinning -- 3.1 Introduction -- 3.2 Topic overview -- 3.3 Melt electrospinning process -- 3.4 Polymers in melt electrospinning -- 3.4.1 Polycaprolactone -- 3.4.2 Polylactic acid -- 3.4.3 Poly(lactic-co-glycolic acid) -- 3.4.4 Polyethylene terephthalate -- 3.4.5 Polyurethane -- 3.4.6 Polyethylene -- 3.4.7 Polypropylene -- 3.4.8 Nylon -- 3.5 System design -- 3.5.1 Syringe-based polymer delivery -- 3.5.1.1 Heating -- 3.5.1.2 Extrusion -- 3.5.2 Other polymer delivery techniques -- 3.5.2.1 Screw extrusion melt electrospinning -- 3.5.2.2 Laser-heated melt electrospinning "The first part of this book deals with the main technological aspects of EFDTs, such as basic technologies, the role of process parameters to impart specific morphological, biochemical, or physical cues able to trigger cell biomaterial and cell-to-cell interactions, and current technological implementations used to encode new scaffold functionalities. The second part of the book addresses applications of EFDTs in biomedical fields, with chapters on their application in tissue engineering, molecular delivery, and implantable devices. This book is a valuable resource for materials scientists, biomedical engineers, and clinicians who are interested in novel technologies for tissue engineering and therapeutic applications"--Back cover