Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Oncology (Medical Radiology)

Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. This is assisting clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. In this book, targeted at both clinical practitioners and basic scientists, the principles of the methods, their practical implementation, and their application to specific tumor types are discussed by the leading authorities in the field today. The book will serve as an invaluable single-volume reference covering all the latest developments in contrast-enhanced oncological MRI. An Introduction to Dynamic Contrast-Enhanced MRI in Oncology....Pages 1-22 Contrast Agents for Magnetic Resonance Imaging....Pages 23-37 The Role of Blood Pool Contrast Media in the Study of Tumor Pathophysiology....Pages 39-52 Quantification of Dynamic Susceptibility Contrast T 2 * MRI in Oncology....Pages 53-67 Measuring Contrast Agent Concentration in T 1 -Weighted Dynamic Contrast-Enhanced MRI....Pages 69-79 Tracer Kinetic Modelling for T 1 -Weighted DCE-MRI....Pages 81-92 Imaging Techniques for Dynamic Susceptibility Contrast-Enhanced MRI....Pages 95-108 Consensus Recommendations for Acquisition of Dynamic Contrasted-Enhanced MRI Data in Oncology....Pages 109-113 Dynamic Contrast-Enhanced MRI in Cerebral Tumours....Pages 117-143 Dynamic Magnetic Resonance Imaging in Breast Cancer....Pages 145-173 Dynamic Contrast-Enhanced MR Imaging for Predicting Tumor Control in Patients with Cervical Cancer....Pages 175-189 Dynamic Contrast-Enhanced MRI of Prostate Cancer....Pages 191-213 Dynamic Contrast-Enhanced MR Imaging in Musculoskeletal Tumors....Pages 215-237 Dynamic Contrast-Enhanced MRI in the Liver....Pages 239-261 Use of Dynamic Contrast-Enhanced MRI in Multi-Centre Trials with Particular Reference to Breast Cancer Screening in Women at Genetic Risk....Pages 265-279 Applications of Dynamic Contrast-Enhanced MRI in Oncology Drug Development....Pages 281-297

Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. The method assists clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. Here, leading authorities discuss the principles of the methods, their practical implementation, and their application to specific tumor types. The text is an invaluable single-volume reference that covers all the latest developments in contrast-enhanced oncological MRI.

"In this book, targeted at both clinical practitioners and basic scientists, the principles of the methods, their practical implementation, and their application to specific tumor types are discussed by the leading authorities in the field today. The book will serve as an invaluable single-volume reference covering all the latest developments in contrast-enhanced oncological MRI."--Jacket