Drugs In Palliative Care (oxford Medical Publications)

Clinical pharmacology overview -- Prescribing guidance -- Drug monographs A-Z. While palliative care has adopted a holistic approach to treatment, medication driven symptom management ostensibly forms the critical aspect of care. Pharmacological therapy can be extremely complex because these patients often have co-existing medical conditions in addition to symptoms caused by their terminal disease. The resulting polypharmacy can be daunting for professionals and can negatively impact on effectiveness of care. The practitioner requires a simple, easy to navigate reference source that provides succinct and pertinent drug information. This detailed yet concise handbook will appeal to a variety of healthcare professionals involved in the provision of palliative care and medicines information. It begins with an overview of pharmacology and prescribing advice then contains over 100 entries of palliative care drugs, in an easy to use A-Z format"--Provided by publisher Contents 12 Symbols and abbreviations 16 1 Clinical pharmacology overview 20 Introduction 21 Pharmacokinetics 22 Pharmacodynamics 26 Pharmacogenetics 30 Drug interactions 34 2 Prescribing guidance 40 Unlicensed use of medicines 41 Legal categories of medicines 42 Independent prescribing: palliative care issues 44 Travelling abroad with medicines 46 Management of pain 48 Management of pain: selection of an NSAID 50 Management of pain: opioid substitution 52 Management of pain: breakthrough cancer pain (BTcP) 54 Management of pain: neuropathic pain 57 Management of pain: poorly controlled pain 59 Management of nausea and vomiting 60 Management of constipation 62 Discontinuing and/or switching antidepressants 64 Continuous subcutaneous infusions 69 Use of drugs in end-of-life care 72 3 Drug monographs A–Z 80 Monographs 82 Alfentanil 84 Allopurinol 87 Amitriptyline 89 Amoxicillin 92 Anastrozole 94 Baclofen 96 Betahistine 99 Bicalutamide 101 Bisacodyl 103 Bisoprolol 105 Buprenorphine 108 Carbamazepine 112 Carbocisteine 116 Celecoxib 117 Ciprofloxacin 121 Citalopram 124 Clonazepam 128 Co-danthramer 131 Codeine 133 Cyclizine 137 Cyproheptadine 140 Cyproterone 142 Dalteparin 144 Demeclocycline 148 Dexamethasone 150 Diamorphine 155 Diazepam 159 Diclofenac 162 Diethylstilbestrol 167 Dihydrocodeine 169 Docusate sodium 172 Domperidone 174 Donepezil 176 Duloxetine 178 Enoxaparin 182 Erlotinib 185 Erythromycin 188 Esomeprazole 191 Etamsylate 194 Etoricoxib 195 Exemestane 198 Fentanyl 200 Finasteride 210 Flucloxacillin 211 Fluconazole 213 Flumazenil 216 Fluoxetine 218 Flutamide 222 Furosemide 224 Gabapentin 227 Gliclazide 230 Glimepiride 233 Glipizide 235 Glyceryl trinitrate (GTN) 237 Glycopyrronium 240 Granisetron 243 Haloperidol 246 Hydromorphone 250 Hyoscine butylbromide 253 Hyoscine hydrobromide 256 Ibuprofen 259 Imatinib 262 Insulin: biphasic insulin aspart 265 Insulin: biphasic insulin lispro 268 Insulin: biphasic isophane insulin 271 Insulin: insulin aspart 274 Insulin: insulin detemir 276 Insulin: insulin glargine 279 Insulin: insulin lispro 282 Insulin: isophane insulin 284 Insulin: soluble 287 Ipratropium bromide 290 Ketamine 292 Ketorolac 296 Lactulose 299 Lansoprazole 301 Letrozole 304 Levomepromazine 306 Lidocaine 309 Loperamide 311 Lorazepam 313 Macrogol ‘3350’ 316 Magnesium hydroxide 318 Magnesium-L-aspartate 320 Magnesium sulphate 322 Medroxyprogesterone 324 Megestrol 327 Metformin 329 Methadone 332 Methylnaltrexone 337 Methylphenidate 339 Metoclopramide 342 Metronidazole 345 Midazolam 348 Mirtazapine 352 Misoprostol 355 Modafinil 357 Morphine 359 Nabumetone 365 Naloxone 368 Naproxen 370 Nifedipine 373 Nitrofurantoin 376 Nystatin 379 Octreotide 380 Olanzapine 382 Omeprazole 386 Ondansetron 390 Oxybutynin 393 Oxycodone 396 Pamidronate disodium 401 Pantoprazole 404 Paracetamol 407 Paroxetine 409 Phenobarbital 413 Pramipexole 416 Prednisolone 419 Pregabalin 423 Propantheline 426 Quinine sulphate 428 Rabeprazole 430 Ranitidine 433 Reboxetine 436 Repaglinide 439 Risperidone 441 Ropinirole 445 Rosiglitazone 448 Salbutamol 450 Salmeterol 453 Senna (sennosides) 456 Sertraline 458 Sevelamer 461 Spironolactone 463 Sucralfate 466 Tamoxifen 468 Tamsulosin 470 Temazepam 472 Thalidomide 474 Theophylline 477 Tiotropium 480 Tolterodine 482 Tramadol 485 Tranexamic acid 490 Trazodone 492 Trimethoprim 495 Venlafaxine 497 Warfarin 501 Zoledronic acid 504 Zolpidem 507 Zopiclone 509 Index 512 A 512 B 513 C 513 D 514 E 515 F 515 G 516 H 516 I 516 J 517 K 517 L 517 M 517 N 518 O 518 P 519 Q 519 R 519 S 520 T 520 U 521 V 521 W 521 Y 521 Z 521