Diagnosis And Management Of Pulmonary Hypertension (respiratory Medicine)

This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment. It discusses the definition and classification of these disorders and the epidemiology of pulmonary arterial hypertension (PAH); explores the approach to diagnosis and evaluation via methods such as echocardiography, right heart catheterization, and cardiopulmonary exercise testing; describes the major drug classes used to treat PAH and the cell signaling pathways that they target as well as adjunct and investigative therapies; and highlights special situations that are particularly challenging in the management of PAH. Written by experts in their respective fields, __Diagnosis and Management of Pulmonary Hypertension__ is a valuable resource for pulmonologists, cardiologists, and practitioners in internal medicine and critical care. Front Matter....Pages i-xiv The Pulmonary Circulation....Pages 1-20 Epidemiology and Disease Classification of Pulmonary Hypertension....Pages 21-35 Pathogenesis of Pulmonary Arterial Hypertension....Pages 37-65 Hypoxic Pulmonary Hypertension....Pages 67-92 Pulmonary Hypertension in Chronic Heart and Lung Disease....Pages 93-113 Chronic Thromboembolic Pulmonary Hypertension....Pages 115-142 Schistosomiasis-Associated Pulmonary Arterial Hypertension....Pages 143-163 Approach to the Patient with Elevated Pulmonary Arterial Pressure....Pages 165-201 Echocardiography....Pages 203-224 Pulmonary Hemodynamics and Right Heart Catheterization....Pages 225-264 Cardiopulmonary Exercise Testing in Pulmonary Hypertension....Pages 265-301 Adjunct Therapy and Calcium Channel Blockers....Pages 303-321 Prostacyclin Therapy for Pulmonary Arterial Hypertension....Pages 323-340 Endothelin Receptor Antagonists....Pages 341-354 Modulation of cGMP Synthesis and Metabolism....Pages 355-375 Combination Therapy for the Treatment of Pulmonary Arterial Hypertension....Pages 377-396 Investigative Therapies in Pulmonary Arterial Hypertension....Pages 397-412 Pulmonary Hypertension in Critically Ill Patients....Pages 413-436 Perioperative Management of Pulmonary Hypertension....Pages 437-464 Erratum to: Echocardiography....Pages E1-E1 Back Matter....Pages 465-474 This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment. It discusses the definition and classification of these disorders and the epidemiology of pulmonary arterial hypertension (PAH); explores the approach to diagnosis and evaluation via methods such as echocardiography, right heart catheterization, and cardiopulmonary exercise testing; describes the major drug classes used to treat PAH and the cell signaling pathways that they target as well as adjunct and investigative therapies; and highlights special situations that are particularly challenging in the management of PAH. Written by experts in their respective fields,℗lDiagnosis and Management of Pulmonary Hypertension℗lis a valuable resource for pulmonologists, cardiologists, and practitioners in internal medicine and critical care. ℗l℗l James R. Klinger, Robert P. Frantz, Editors. Includes Bibliographical References And Index. Mode Of Access: World Wide Web.