Diätetik und Arteriosklerose : 6. Tagung der Deutschen Gesellschaft für Arterioskleroseforschung 1992

H. E. Schaefer Pathologisches Institut, Universität Freiburg Dieser Band berichtet über die 6. Arbeitstagung der Deutschen Gesellschaft für Arterioskleroseforschung, die vom 5. bis 7. April 1992 am nun schon gewohnten Tagungsort, im Heinrich Fabri-Institut in Blaubeuren, stattgefunden hat. Dieses Haus bietet die Möglichkeit, am gleichen Ort zu tagen und zu wohnen, und garantiert insofern ideale Rahmenbedingungen für einen intensiven Gedanken­ austausch. In einer besonderen Feierstunde dankte die Gesellschaft dem Präsidenten der Universität Tübingen, Herrn Dr. A. Theis, für das bereits mehrjährig genossene Gastrecht, insbesondere aber auch ihrem Sponsor der ersten Stunde, Herrn Ehrensenator Adolf Merckle, Inhaber der Firma Merckle GmbH - Chemisch-Pharmazeutische Fabrik/Blaubeuren, für die großzügige Finanzierung dieser Tagung. Einen besonderen Akzent erfuhr diese Tagung durch die erstmalige Verleihung des W. H. Hauss-Preises an Herrn Dr. H. A. Lehr vom Institut für Chirurgische Experimentalforschung der Ludwig-Maximilians-Universität München für seine Arbeit "Superoxide-dependent stimulation of leukocyte adhesion by oxidatively modified low density lipoprotein in vivo". Über Inhalt und Bedeutung dieser Forschungen zur Thematik der Stimulation von Leukozyten durch oxidativ modifizierte LDL kann sich der Leser durch einen weiterführenden Beitrag der Arbeitsgruppe um Herrn Dr. Lehr in diesem Tagungsband informieren. Je ein Preis für den besten Vortrag sowie für das beste Poster der Tagung wurden an die Autoren Dr. M. Thie (Münster) und D. Axel (Tübingen) verliehen. Diese neu eingerichteten Preise sind dankenswerter Weise von der Firma Lichtwer Pharma GmbHlBerlin gestiftet worden. Front Matter....Pages 1-17 Aktuelle Fragen zur Genese und Therapie der Atherosklerose....Pages 18-31 Betrachtungen zur Entwicklung von Therapie und Prävention der Arteriosklerose....Pages 32-42 The role of vitamin E in the pathogenesis of arteriosclerosis....Pages 43-53 Effect of monounsaturated fatty acids on lipid metabolism and its relation to dietary cholesterol content and apolipoprotein E polymorphism....Pages 54-62 Studies of the behaviour of the omega-3-fatty acids in coronary sclerosis....Pages 63-67 Effects of fish oil on lipid metabolism in hemodialysis patients....Pages 68-76 Inhibition of cholesterol-biosynthesis in cultured hepatocytes by garlic components....Pages 77-82 Influence of garlic on atherogenesis in rats....Pages 83-87 Garlic — an anti-arteriosclerotic natural remedy?....Pages 88-93 Modification of fat intake in type II-diabetics: What can be achieved?....Pages 94-100 Determination of synthesis and absorption of cholesterol: Influence of apo E polymorphism, dietary cholesterol, and dietary fatty acids....Pages 101-110 Postprandial redistribution of apo E isoforms in triglyceride-rich lipoproteins....Pages 111-120 The role of the liver in postprandial hypertriglyceridaemia....Pages 121-130 Lipoprotein levels following oral fat intake in patients with coronary heart disease....Pages 131-139 CAD risk profile of the working people in the Dresden area one year after the political changes (DRECAN study)....Pages 140-148 Increase in plasma HDL cholesterol in vitro — influence of cells and plasmatic factors....Pages 149-157 Results of coronary angiography following long term treatment with LDL apheresis and lipid-lowering therapies in patients with familial hypercholesterolemia and myocardial infarct....Pages 158-170 Hypertriglyceridaemia (HTG) as independent risk factor for myocardial infarction in type 2 diabetes: The Diabetes Intervention Study....Pages 171-177 The LDL Apheresis Register of the German Society of Atherosclerosis Research — First Results —....Pages 178-184 Risk factor prevalence for coronary heart disease obtained during an informational campaign in Münster, Westfalen, Germany....Pages 185-193 High waist-to-hip ratios in a population of the former G.D.R.: The Freiberg Study....Pages 194-198 Lp(a) distribution in the Dresden population. The DRECAN-study....Pages 199-207 The frequency of the apo E type 4/3 in patients with angiographically determined coronary artery disease....Pages 208-213 Impaired in vivo metabolism of HDL in familial hypercholesterolemia....Pages 214-221 Clinical characterization and long term treatment of patients with hyperlipoproteinemia type III....Pages 222-231 Clinical and animal experimental aspects of lipid metabolism disorders in erectile dysfunction....Pages 232-244 The influence of duration and pressure on the acute results of percutaneous transluminal coronary angioplasty in patients with stenosing coronary arteriosclerosis....Pages 245-251 Does lipoprotein (a) influence the rate of restenosis following balloon dilatation?....Pages 252-258 Detection of macrophages following experimental balloon angioplasty....Pages 259-264 Cellular alteration after experimental directional peripheral atherectomy....Pages 265-270 Intimal reaction and incidence of thrombotic occlusions following experimental stent implantation and balloon dilatation in rabbits....Pages 271-280 Analysis of immunhistochemical differences of macrophages in arteriosclerotic biopsies from directional coronary atherectomy....Pages 281-288 Atherectomy with a Simpson-Catheter of the femoro-popliteal vessels: cell biological investigation of the plaque material obtained....Pages 289-296 Lokalisation von basic Fibroblast Growth Factor (bFGF) in Normalgewebe und in Atherektomiegewebe arteriosklerotischer Gefäßwandläsionen....Pages 297-301 Influence of the position of intravascular ultrasound catheters on the depiction of cross sectional areas in arterial vessels....Pages 302-307 Assessment of arteriosclerotic peripheral vessels by intravascular ultrasound: in vitro investigations....Pages 308-316 Evaluation of duplex sonography in clinical studies of progressions/regressions in arteriosclerosis....Pages 317-322 Extended functional relevance of significant coronary stenoses visualized by TI-201 Myocard SPECT: additional information obtained from reinjection studies in the presence of collaterals....Pages 323-328 The role of quantitative coronary angiography in clinical studies on the progression/regression of arteriosclerosis....Pages 329-334 The influence of proteins and lipoproteins on plasma viscosity....Pages 335-342 Fibrinogen in patients with coronary heart disease: relationship to lipoproteins....Pages 343-346 Fibrinogen, a secondary risk factor for stroke patients....Pages 347-352 Sulfated polysaccharides act as modulators of cell proliferation and expression of extracellular matrix proteins — fibronectin and thrombospondin — in arterial wall cells....Pages 353-363 Extracellular matrix control of smooth muscle cell activity....Pages 364-370 Mutual influence on collagen synthesis and proliferation by TGF-β 1 and PDGF-A/B in arterial smooth muscle cells....Pages 371-381 Detection of EGF receptor mRNA in human arteriosclerotic lesions....Pages 382-393 Effects of nicotine on endothelial and smooth muscle cell proliferation in experimentally preformed fibromuscular plaques....Pages 394-401 Radical-induced leukocyte adhesion to the endothelium caused by injection of oxidized low density lipoprotein in vivo....Pages 402-408 Efficacy and tolerability of simvastatin in primary hypercholesterolemia....Pages 409-414 Immunolocalization of lipoproteins in human arteriosclerotic tissue....Pages 415-424 The effect of cytostatic agents on plaque cells of human atherosclerotic lesions: Dose reduction by a combined drug regime?....Pages 425-430 Reduction of human plaque smooth muscle cell proliferative and migratory activities by calcium antagonists....Pages 431-439 Growth pattern of human endothelial cells after compression with 3 bar in vitro....Pages 440-444 Differences in growth behaviour of human vascular smooth muscle cells in culture....Pages 445-449 Fusion of smooth muscle cells with mouse macrophages....Pages 450-456 Immunohistochemical detection of proliferation of smooth muscle cells after experimental angioplasty: comparison of BrdU incorporation and PCNA expression....Pages 457-461 Expression von mRNA für Kollagene in glatten Muskelzellen aus der Aorta unter verschiedenen Kulturbedingungen....Pages 462-468 Effect of different growth factors on the migration and proliferation of human smooth muscle cells....Pages 469-475 Bovine pericytes and smooth muscle cells in culture — a comparative study....Pages 476-483 Analysis of lateral mobility of molecules in the membrane of coronary plaque cells by measuring fluorescence recovery after photobleaching....Pages 484-492 Release of interleukin-6 (IL-6) from human vascular smooth muscle cells....Pages 493-499 Wachstumsstimulation von Gefäßmuskelzellen des Menschen durch Adrenalin im Transfilter-Co-Kultursystem: Hemmung durch den Alpha 1 -Antagonisten Urapidil?....Pages 500-506 Modified lipoproteins influence the biosynthetic activity of vascular smooth muscle cells....Pages 507-514 Arteriosclerosis in rabbits after balloon dilatation of the aorta....Pages 515-521 Pharmacological inhibition of atherosclerosis in diet-induced and genetically hypercholesterolemic rabbits....Pages 522-528 Suppression of coronary arteriosclerosis and myocardial sclerosis by gallopamil in Skelton-hypertensive rats....Pages 529-535 The ACE inhibitor Enalapril and the angiotensin II receptor antagonist Losartan inhibit neointimal thickening in balloon-injured rat carotid arteries....Pages 536-540 New aspects in the analysis of atherosclerotic vessel wall lesions....Pages 541-547 Changes in the cellular density of plaques in relation to cholesterol diet in experimental atherosclerosis....Pages 548-554 New aspects about the role of cytosolic free sodium in the pathogenesis of essential hypertension....Pages 555-559 Circadian blood pressure rhythmicity in the elderly patient....Pages 560-566 Vasopressorische Wirkung von Extrakten aus humaner Nebenschilddrüse....Pages 567-574 Study of the Ca 2+ ATPase activity and intracellular electrolyte concentration in red blood cells and platelets of essential and secondary hypertensives....Pages 575-580 Back Matter....Pages 581-584