Diabetes and the Nervous System (Volume 126) (Handbook of Clinical Neurology, Volume 126)

This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson’s disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system. * Offers a unique emphasis on the neurological manifestations of diabetes * Provides thorough coverage of the clinical, experimental, mechanistic, therapeutic, peripheral, and central aspects of diabetic neuropathy * Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available Content: Series Page Page ii Copyright Page iv Handbook of Clinical Neurology 3rd Series Pages v-vi Foreword Page vii Michael J. Aminoff, François Boller, Dick F. Swaab Preface Page ix Douglas W. Zochodne, Rayaz A. Malik Contributors Pages xi-xiv Chapter 1 - Epidemiology of polyneuropathy in diabetes and prediabetes Pages 3-22 Dan Ziegler, Nikolaos Papanas, Aaron I. Vinik, Jonathan E. Shaw Chapter 2 - Clinical features of diabetic polyneuropathy Pages 23-30 Douglas W. Zochodne Chapter 3 - Focal and entrapment neuropathies Pages 31-43 Benn E. Smith Chapter 4 - Diabetic radiculoplexus neuropathies Pages 45-52 Ruple S. Laughlin, P. James B. Dyck Chapter 5 - Painful diabetic neuropathy: clinical aspects Pages 53-61 Triantafyllos Didangelos, John Doupis, Aristidis Veves Chapter 6 - Diabetic autonomic neuropathy Pages 63-79 Roy Freeman Chapter 7 - Motor neuropathy Pages 81-95 Henning Andersen Chapter 8 - Diabetic neuropathy and foot complications Pages 97-107 Andrew J.M. Boulton Chapter 9 - Glucose intolerance, metabolic syndrome, and neuropathy Pages 109-122 Melissa Cortez, J. Robinson Singleton, A. Gordon Smith Chapter 10 - Diabetic neuropathy in children Pages 123-143 Jean K. Mah, Danièle Pacaud Chapter 11 - Cognitive disorders in diabetic patients Pages 145-166 Paula S. Koekkoek, Guy E.H.M. Rutten, Geert Jan Biessels Chapter 12 - Stroke and diabetes mellitus Pages 167-174 Michael D. Hill Chapter 13 - Neurologic infections in diabetes mellitus Pages 175-194 Cheryl A. Jay, Marylou V. Solbrig Chapter 14 - Recognition and management of psychosocial issues in diabetic neuropathy Pages 195-209 Loretta Vileikyte, Jeffrey S. Gonzalez Chapter 15 - General aspects of diabetes mellitus Pages 211-222 Uazman Alam, Omar Asghar, Shazli Azmi, Rayaz A. Malik Chapter 16 - Sexual dysfunction in diabetes Pages 223-232 Tamás Várkonyi, Peter Kempler Chapter 17 - Electrophysiologic testing in diabetic neuropathy Pages 235-248 Bruce Perkins, Vera Bril Chapter 18 - Pathology of human diabetic neuropathy Pages 249-259 R.A. Malik Chapter 19 - Epidermal innervation in diabetes Pages 261-274 Gigi Ebenezer, Michael Polydefkis Chapter 20 - Clinical and diagnostic features of small fiber damage in diabetic polyneuropathy Pages 275-290 S. Javed, I.N. Petropoulos, M. Tavakoli, R.A. Malik Chapter 21 - Central nervous system imaging in diabetic cerebrovascular diseases and white matter hyperintensities Pages 291-315 Simerpreet Bal, Mayank Goyal, Eric Smith, Andrew M. Demchuk Chapter 22 - Therapy for diabetic neuropathy: an overview Pages 317-333 Bernadette Calabek, Brian Callaghan, Eva L. Feldman Chapter 23 - Methodology for conduct of epidemiologic surveys and randomized controlled trials of diabetic polyneuropathy Pages 335-338 Peter James Dyck Chapter 24 - Neuroscience of glucose homeostasis Pages 341-351 S.E. La Fleur, E. Fliers, A. Kalsbeek Chapter 25 - Mechanisms of disease: Mitochondrial dysfunction in sensory neuropathy and other complications in diabetes Pages 353-377 Paul Fernyhough, Jonathan McGavock Chapter 26 - Mechanisms of diabetic neuron damage: Molecular pathways Pages 379-399 Douglas W. Zochodne Chapter 27 - Mechanisms of diabetic neuropathy: Schwann cells Pages 401-428 Andrew P. Mizisin Chapter 28 - Mechanisms of diabetic neuropathy: axon dysfunction Pages 429-442 Anders A.F. Sima, Weixian Zhang Chapter 29 - Mechanisms of disease: role of neurotrophins in diabetes and diabetic neuropathy Pages 443-460 Valerie M.K. Verge, Christer S. Andreassen, Terra G. Arnason, Henning Andersen Chapter 30 - Experimental motor neuropathy in diabetes Pages 461-467 Natalie M. Wilson, Douglas E. Wright Chapter 31 - Ischemia and diabetic neuropathy Pages 469-487 Hitoshi Nukada Chapter 32 - Diabetes and neurodegeneration in the brain Pages 489-511 Cory Toth Chapter 33 - Neurologic damage in hypoglycemia Pages 513-532 Simin Mohseni Chapter 34 - Painful neuropathy: Mechanisms Pages 533-557 Corinne A. Lee-Kubli, Nigel A. Calcutt Chapter 35 - Insights into the pathogenesis and treatment of painful diabetic neuropathy Pages 559-578 Marni Greig, Solomon Tesfaye, Dinesh Selvarajah, Iain D. Wilkinson Chapter 36 - Autonomic neuropathy in experimental models of diabetes mellitus Pages 579-602 Robert E. Schmidt Index Pages 603-615 "This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson's disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system"--Publisher's description