Developmental biology using purified genes: Proceedings of the 1981 ICN-UCLA Symposia on Developmental Biology Using Purified Genes, held in Keystone, ... symposia on molecular and cellular biology)

Developmental Biology Using Purified Genes is a compilation of papers presented at the 1981 ICN-UCLA Symposia on Developmental Biology Using Purified Genes, held in Keystone, Colorado. Contributors representing a wide range of disciplines explore the mechanisms underlying gene control of development and explain how purified genes are transcribed in cells, how DNA sequences and non-DNA molecules regulate development, and how gene-control molecules or other developmental determinants are unequally distributed among embryonic cells. Organized into nine sections comprised of 54 chapters, this volume begins with an overview of the mechanism by which gene activity is regionally controlled and its role in development. It then proceeds with a discussion on eukaryotic genes and their structure, including the collagen gene and the albumin gene family. The next chapters focus on the transcription and translation of yolk protein mRNA in the fat bodies of Drosophila, the organization and expression of the actin multi-gene family in Dictyostelium, the cDNA clones encoding mouse transplantation antigens, and the role of double minute chromosomes in unstable methotrexate resistance. The book also introduces the nucleosome core particle, regulatory factors involved in the transcription of mouse ribosomal genes, and developmental control of 5S RNA gene expression before concluding with a chapter on synthetic oligodeoxyribonucleotides and their use in the isolation of specific cloned DNA sequences. This book will be of interest to microbiologists, molecular biologists, embryologists, geneticists, and researchers working in the fields of genetics and developmental biology. Content: Academic Press Rapid Manuscript Reproduction , Page ii Front Matter , Page iii Copyright , Page iv CONTRIBUTORS , Pages xi-xx PREFACE , Page xxi CONCEPTS OF GENE CONTROL IN DEVELOPMENT , Pages 1-10 THE DOPA DECARBOXYLASE GENE LOCUS OF DROSOPHILA MELANOGASTER : ORIENTATION OF THE GENE AND PRELIMINARY MAPPING OF GENETIC MARKERS , Pages 11-16 TISSUE-SPECIFIC EXPRESSION OF MOUSE ALPHA-AMYLASE GENES , Pages 17-24 THE COLLAGEN GENE , Pages 25-39 THE ALBUMIN GENE FAMILY , Pages 41-50 Expression of β-like Globin Genes During Rabbit Embryogenesis , Pages 51-60 INTERVENING SEQUENCE MUTATION IN A CLONED HUMAN β + -THALASSEMIC GLOBIN GENE , Pages 61-70 STRUCTURES IN INTERGENIC DNA OF NON-ALPHA GLOBIN GENES OF MAN , Pages 71-84 SEQUENCES OF A HUMAN FIBROBLAST INTERFERON GENE AND TWO LINKED HUMAN LEUKOCYTE INTERFERON GENES , Pages 85-96 TRANSCRIPTION AND TRANSLATION OF YOLK PROTEIN mRNA IN THE FAT BODIES OF DROSOPHILA , Pages 97-106 ORGANIZATION AND EXPRESSION OF THE ACTIN MULTI-GENE FAMILY IN DICTYOSTELIUM , Pages 107-116 THE ACTIN GENES OF DROSOPHILA : HOMOLOGOUS PROTEIN CODING REGIONS WITH DISTINCT STRUCTURAL ARRANGEMENTS AND CHROMOSOMAL LOCATIONS , Pages 117-124 A CLUSTER OF DROSOPHILA CUTICLE GENES , Pages 125-133 ORGANIZATION AND EVOLUTION OF THE DEVELOPMENTALLY REGULATED SILKMOTH CHORION GENE FAMILIES , Pages 135-153 THE PROTAMINE MULTI-GENE FAMILY IN THE DEVELOPING RAINBOW TROUT TESTES/ANALYSIS OF THE ds-cDNA CLONES , Pages 155-172 ISOLATION AND CHARACTERIZATION OF cDNA CLONES ENCODING MOUSE TRANSPLANTATION ANTIGENS , Pages 173-188 DEVELOPMENTAL GENETICS OF THE BITHORAX COMPLEX IN DROSOPHILA , Pages 189-208 GENETIC DISSECTION OF EMBRYOGENESIS IN CAENORHABDITIS ELEGANS , Pages 209-227 Genes Coding for Metal Induced Synthesis of RNA Sequences Are Differentially Amplified and Regulated in Mammalian Cells , Pages 229-237 METALLOTHIONEIN-I GENE AMPLIFICATION IN CADMIUM-RESISTANT MOUSE CELL LINES , Pages 239-248 THE ROLE OF DOUBLE MINUTE CHROMOSOMES IN UNSTABLE METHOTREXATE RESISTANCE , Pages 249-257 MODULATION OF THE STRUCTURE OF THE NUCLEOSOME CORE PARTICLE DURING DEVELOPMENT , Pages 259-274 EVIDENCE FOR A STRUCTURAL ROLE OF COPPER IN HISTONE-DEPLETED CHROMOSOMES AND NUCLEI , Pages 275-292 DROSOPHILA HIGH MOBILITY GROUP PROTEINS , Pages 293-301 REGULATORY FACTORS INVOLVED IN THE TRANSCRIPTION OF MOUSE RIBOSOMAL GENES , Pages 303-312 ELEMENTS REQUIRED FOR INITIATION OF TRANSCRIPTION OF THE OVALBUMIN GENE IN VITRO , Pages 313-329 IDENTIFICATION OF A TRANSCRIPTIONAL CONTROL REGION UPSTREAM FROM THE HSV THYMIDINE KINASE GENE , Pages 331-345 EXPRESSION OF β-GLOBIN GENES MODIFIED BY RESTRUCTURING AND SITE-DIRECTED MUTAGENESIS , Pages 347-366 MODIFICATION OF THE RABBIT CHROMOSOMAL β-GLOBIN GENE BY RESTRUCTURING AND SITE-DIRECTED MUTAGENESIS , Pages 367-385 TRANSCRIPTION OF ADENOVIRUS DNA IN INFECTED CELL EXTRACTS , Pages 387-399 CHARACTERIZATION OF FACTORS THAT IMPART SELECTIVITY TO RNA POLYMERASE II IN A RECONSTITUTED SYSTEM , Pages 401-414 EXPRESSION OF THE HEAT SHOCK GENES IN DROSOPHILA MELANOGASTER , Pages 415-427 ANALYSIS OF EUKARYOTIC GENE TRANSCRIPTION IN VITRO , Pages 429-446 STUDIES ON THE DEVELOPMENTAL CONTROL OF 5S RNA GENE EXPRESSION , Pages 447-461 INFLUENCE OF 5′ FLANKING SEQUENCES ON tRNA TRANSCRIPTION IN VITRO , Pages 463-472 TRANSCRIPTION INITIATION AND TERMINATION SIGNALS IN THE YEAST SUP4 tRNA Tyr GENE , Pages 473-482 PROCESSING OF YEAST tRNA TYR IN XENOPUS OOCYTES MICROINJECTED WITH CLONED GENES , Pages 483-492 THE CONTROL OF ADENOVIRUS VA I RNA TRANSCRIPTION , Pages 493-505 REGULATION OF ADENOVIRUS VA RNA GENE EXPRESSSION , Pages 507-514 RETROVIRUS ONCOGENES , Pages 515-524 ISOLATION OF A NEW NONDEFECTIVE ADENOVIRUS-SV40 HYBRID VIRUS FROM IN VITRO CONSTRUCTED DEFECTIVE VIRUSES , Pages 525-533 CONSTRUCTION AND TRANSFER OF RECOMBINANT RETROVIRUS CLONES CARRYING THE HSV-1 THYMIDINE KINASE GENE , Pages 535-546 RAT INSULIN GENE COVALENTLY LINKED TO BOVINE PAPILLOMAVIRUS DNA IS EXPRESSED IN TRANSFORMED MOUSE CELLS , Pages 547-556 THE DEVELOPMENT OF HOST VECTORS FOR DIRECTED GENE TRANSFERS IN PLANTS , Pages 557-575 THE TI PLASMID AS A VECTOR FOR THE GENETIC ENGINEERING OF PLANTS , Pages 577-585 USE OF CAULIFLOWER MOSAIC VIRUS DNA AS A MOLECULAR VEHICLE IN PLANTS , Pages 587-594 EVIDENCE FOR THE TRANSFORMATION OF DICTYOSTELIUM DISCOIDEUM WITH HOMOLOGOUS DNA , Pages 595-605 NUCLEAR AND GENE TRANSPLANTATION IN THE MOUSE , Pages 607-619 RESTRICTION ENDONUCLEASES, DNA SEQUENCING, AND COMPUTERS , Pages 621-634 HIGH RESOLUTION TWO-DIMENSIONAL RESTRICTION ANALYSIS OF METHYLATION IN COMPLEX GENOMES , Pages 635-646 A RAPID AND SENSITIVE IMMUNOLOGICAL METHOD FOR IN SITU GENE MAPPING , Pages 647-658 A STRATEGY FOR HIGH-SPEED DNA SEQUENCING , Pages 659-669 IN VITRO CONSTRUCTION OF SPECIFIC MUTANTS , Pages 671-682 USE OF SYNTHETIC OLIGODEOXYRIBONUCLEOTIDES FOR THE ISOLATION OF SPECIFIC CLONED DNA SEQUENCES , Pages 683-693 INDEX , Pages 695-702