Development and aging in the nervous system : proceedings of a symposium ... held in Miami, Florida, February 19-20, 1973

Development and Aging in the Nervous System covers the proceedings of a series of symposia by the same title, held at the University of Miami Training Program in Cellular Aging on February 19-20, 1973. This book is composed of 11 chapters that specifically consider aging in its total sense, from embryonic development through senescence of a vital organ system of the body. The introductory chapters review the age changes in the neuronal microenvironment and the regulative mechanism of neuronal death in cell number control in the nervous system. The next chapters deal with the neuronal degeneration in aging mammals, the selected changes in the developing postnatal rat, and the trophic influences in the mammalian central nervous system. These topics are followed by discussions of the genesis of neuronal locus specificity, the vertebrate brain aging, and the neurochemical patterns in the developing and aging brain. The remaining chapters describe the mechanisms of enzymatic differentiation in the brain and in cultured cells and the monoamine metabolism in the aging male mouse. This book will prove useful to development and cell biologists, researchers, and advance students. Content: ACADEMIC PRESS RAPID MANUSCRIPT REPRODUCTION , Page ii Front Matter , Page iii Copyright , Page iv CONTRIBUTORS , Page vii PREFACE , Pages ix-x , Morris Rockstein AGE CHANGES IN THE NEURONAL MICROENVIRONMENT , Pages 1-17 , William Bondareff NEURONAL DEATH AS A REGULATIVE MECHANISM IN THE CONTROL OF CELL NUMBER IN THE NERVOUS SYSTEM , Pages 19-41 , W. Maxwell Cowan NEURONAL DEGENERATION IN AGING MAMMALS , Pages 43-61 , Kalidas Nandy SELECTED CHANGES IN THE DEVELOPING POSTNATAL RAT BRAIN , Pages 63-88 , Donald H. Ford TROPHIC INFLUENCES IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM , Pages 89-103 , John C. Eccles GENESIS OF NEURONAL LOCUS SPECIFICITY , Pages 105-119 , Marcus Jacobson AGING OF THE VERTEBRATE BRAIN , Pages 121-133 , Harold Brody INSULTS TO THE BRAIN. DIFFERENTIAL EFFECTS OF AGING , Pages 135-149 , Frederick Richardson NEUROCHEMICAL PATTERNS IN THE DEVELOPING AND AGING BRAIN , Pages 151-169 , Williamina A. Himwich MECHANISMS OF ENZYMATIC DIFFERENTIATION IN THE BRAIN AND IN CULTURED CELLS , Pages 171-198 , Jean de Vellis MONOAMINE METABOLISM IN THE AGING MALE MOUSE , Pages 199-218 , Caleb E. Finch Edited By Morris Rockstein. Associate Editor: Marvin L. Sussman. Includes Bibliographies.