Design, Synthesis, Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica-Based Drug Delivery Nanosystems (Springer Theses)

This thesis reports on essential advances in the design, synthesis and biomedical applications of multifunctional Mesoporous Silica Nanoparticles (MSNs). It provides several examples of multifunctional MSN-based drug delivery nanosystems and demonstrates successful synergistic cancer therapies combining MSNs and high-intensity focused ultrasound. The book will especially be of interest to researchers and graduate students in the fields of biomaterials, biology, chemistry, medicine and the life sciences who are working to develop new methods and technologies to combat cancer. Front Matter....Pages i-xiii Research Background....Pages 1-30 Synthesis of Hollow Mesoporous Silica Nanoparticles by Silica-Etching Chemistry for Biomedical Applications....Pages 31-46 Multifunctional Mesoporous Silica Nanoparticles for Theranostics of Cancer....Pages 47-64 Hollow Mesoporous Silica Nanoparticles for Ultrasound-Based Cancer Diagnosis and Therapy....Pages 65-83 Summary and Outlook....Pages 85-88