Degenerative retinal diseases : [proceedings of the VII International Symposium on Retinal Degeneration, held October 5-9, 1996, in Sendai, Japan

Since 1984, we have organized Satellite Symposia on Retinal Degenerations that are held in conjunction with the biennial International Congress of Eye Research. The timing and location of our Retinal Degeneration Symposia have all owed scientists and clinicians from around the world to convene and present their exciting new findings. The symposia have been arranged to allow ample time for discussions and one-on-one interactions in a relaxed atmos­ phere, where international friendships and collaborations could be established. The II International Symposium (also known as the Sendai Symposium on Retinal Degeneration) was held in 1986 in Sendai, Japan, on the occasion of the retirement of Kat­ suyoshi Mizuno as Professor and Chairman of Ophthalmology at Tohoku Medical SchooL On October 5-9, 1996, we returned to Sendai, where the VII International Symposium was held at the Miyagi Zao resort hotel in the beautiful Mt. Zao region of northern Japan. This meeting was held on the occasion of the tenth anniversary of Makoto Tarnai as Pro­ fessor and Chairman of Ophthalmology at Tohoku Medical School. One afternoon of the meeting contained a special symposium in honor of Professor Tarnai, who has signifi­ cantly elevated the level and intensity of research on retinal degenerations at his university and in Japan during this past decade. Front Matter....Pages i-xiii Histochemical Comparison of Ocular “Drusen” in Monkey and Human....Pages 1-10 TIMP-3 Accumulation in Bruch’s Membrane and Drusen in Eyes From Normal and Age-Related Macular Degeneration Donors....Pages 11-15 Photoreceptor Rosettes in Age-Related Macular Degeneration Donor Tissues....Pages 17-21 Central Retinal Sensitivity Repeated Measurements as Long Term Follow-Up in Retinitis Pigmentosa....Pages 23-29 Complete And Incomplete Type Congenital Stationary Night Blindness (CSNB) as a Model of “Off-Retina” and “On-Retina”....Pages 31-41 A Family with X-Linked Cone Dystrophy Showing a Tapetal-Like Reflex....Pages 43-50 Autoimmune Retinopathy....Pages 51-56 Norrie Disease in Japan....Pages 57-60 Development of a Model for Macular Degeneration....Pages 61-70 Subretinal Iodoacetate....Pages 71-80 Hereditary Retinal Dystrophy of Swedish Briard Dogs....Pages 81-87 The Vpp Mouse....Pages 89-97 Altered Regulation of Ion Channels in Cultured Retinal Pigment Epithelial Cells From Rcs Rats....Pages 99-106 Structures of the Oligosaccharides of Rhodopsin from Normal and Rcs Rats....Pages 107-114 Indocyanine Green Videoangiography in the Royal College of Surgeons Rat....Pages 115-119 Defective Choroidal Angiogenesis Precedes Retinal Pigment Epithelial Phagocytic Defect in Neonatal Rcs Rats....Pages 121-134 Comparative Biology of Retinoid Deprivation and Replacement in Flies and Rodents....Pages 135-143 Rhodopsin-Dependent Models of Drosophila Photoreceptor Degeneration....Pages 145-158 Recessive Degeneration of Photoreceptor Cells Caused by Point Mutations in the Cytoplasmic Domains of Drosophila Rhodopsin....Pages 159-170 Nitric Oxide-Induced Increases in Retinal cGMP....Pages 171-180 Glycohistochemical Study of Light-Induced Retinal Degeneration....Pages 181-191 Light-Induced Retinal Degeneration is Prevented in Mice Lacking c-fos ....Pages 193-198 Ischemic Neuronal Death in the Fish Retina....Pages 199-204 Isolation of Candidate Genes for Retinal Degenerations....Pages 205-226 Studies on the Cone Cyclic GMP-Phosphodiesterase α’ Subunit Gene....Pages 227-236 Mutations in PDE6A , the Gene Encoding the α-Subunit of Rod Photoreceptor Cgmp-Specific Phosphodiesterase, are Rare in Autosomal Recessive Retinitis Pigmentosa....Pages 237-244 Molecular Analysis of the Human PEDF Gene, a Candidate Gene for Retinal Degeneration: Localization To 17p13.3....Pages 245-254 Screening of Candidate Genes on Japanese Retinal Dystrophies....Pages 255-261 Strategies for the Genetic Analysis of Autosomal Recessive Retinitis Pigmentosa in Spanish Families....Pages 263-275 Progress in Positional Cloning of RP10 (7q31.3), RP1 (8q11–q21), and VMD1 (8q24)....Pages 277-289 Growth Factors In The Retina....Pages 291-294 Genetic and Physical Localisation of the Gene Causing Cone-Rod Dystrophy ( CORD2 )....Pages 295-302 Usher Syndrome Type 1C....Pages 303-312 Oguchi Disease, Retinitis Pigmentosa, and the Phototransduction Pathway....Pages 313-318 A Patient with Progressive Retinal Degeneration Associated with Homozygous 1147delA Mutation in the Arrestin Gene....Pages 319-322 bFGF Transfected Iris Pigment Epithelial Cells Rescue Photoreceptor Cell Degeneration in RCS Rats....Pages 323-328 Transplantation of Neonatal Neural Retina in Photoreceptor Degeneration of Cats....Pages 329-338 Mechanical Aspects of Retinal Pigment Epithelial Transplantation....Pages 339-345 Midkine from Various Sources in Constant Light-Induced Photoreceptor Degeneration of the Rat....Pages 347-352 The Influence of Oxygen on the Survival and Death of Photoreceptors....Pages 353-367 Histological Method to Assess Photoreceptor Light Damage and Protection by Survival Factors....Pages 369-384 Further Studies on the Phagocytosis of Photoreceptor Outer Segments by Rat Retinal Pigment Epithelial Cells....Pages 385-397 Purification and Characterization of Matrix Metalloproteinase-3 (Stromelysin-1) from Bovine Interphotoreceptor Matrix....Pages 399-407 Senile Retinal Deficiencies in Astrocytes and Blood Vessels....Pages 409-415 Back Matter....Pages 423-426