Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

Identifying the causative agent of an infectious disease is a notoriously tricky, but vitally important, business. When faced with new potential pathogens, the principles fostered by Koch's postulates are as relevant today as they were over a century ago. EDITORIAL......Page 2 HIGHLIGHTS......Page 3 NEWS & ANALYSIS......Page 8 Listeria monocytogenes:a multifaceted model......Page 10 Signalling and oxidant adaptationin Candida albicans and Aspergillusfumigatus......Page 22 The interaction of bacterialpathogens with platelets......Page 32 The versatile ε-proteobacteria:key players in sulphidic habitats......Page 45 Advances in tuberculosis vaccinestrategies......Page 56 The trypanolytic factor ofhuman serum......Page 64