Current Research And Clinical Management Of Melanoma (cancer Treatment And Research)

In our environmentally conscious society, reports of an increase in the risk of developing several cancers - including melanoma, lymphoma and lung cancer - have excited great controversy. Of these tumors, melanoma has demonstrated the most spectacular increase, generating a considerable body of research. The justification for this volume is found in the need for an up-to-date review of this research. The book represents a comprehensive review of both current research and clinical management of melanoma, arranged in such a way as to be maximally user-friendly to both the basic scientst and the clinician interested in this fascinating disease. Front Matter....Pages i-xii Etiology of melanoma....Pages 1-28 Epidemiology of melanoma....Pages 29-56 Early detection of melanoma....Pages 57-67 The role of microscopic evaluation in the management of cutaneous melanoma....Pages 69-102 The prevention of cutaneous malignant melanoma: High-risk groups, chemoprevention, education, and screening....Pages 103-140 The natural history of melanoma, including the pattern of metastatic spread and the biological basis for metastases — staging of melanoma....Pages 141-160 Intraocular melanomas....Pages 161-199 Molecular genetics of human malignant melanoma....Pages 201-255 Immunology and immunotherapy of melanoma....Pages 257-277 Positive and negative growth regulation in melanoma: Growth factors, intracellular signalling, and the cell cycle....Pages 279-296 The role of surgery in cutaneous malignant melanoma....Pages 297-334 Chemotherapy of malignant melanoma....Pages 335-354 Radiotherapy of melanoma....Pages 355-371 Back Matter....Pages 372-388 The papers collected in this volume are those presented at the seventeenth Collo­ quium arranged by the Societe Universitaire Europeenne de Recherches Financieres (SUERF), which took place in Berlin in October 1992.