Critical needs and gaps in understanding prevention, amelioration, and resolution of lyme and other tick-borne diseases : the short-term and long-term outcomes : workshop report

A Single Tick Bite Can Have Debilitating Consequences. Lyme Disease Is The Most Common Disease Carried By Ticks In The United States, And The Number Of Those Afflicted Is Growing Steadily. If Left Untreated, The Diseases Carried By Ticks--known As Tick-borne Diseases--can Cause Severe Pain, Fatigue, Neurological Problems, And Other Serious Health Problems. The Institute Of Medicine Held A Workshop October 11-12, 2010, To Examine The State Of The Science In Lyme Disease And Other Tick-borne Diseases.--publisher's Website. Committee On Lyme Disease And Other Tick-borne Diseases: The State Of The Science, Board On Population Health And Public Health Practice, Institute Of Medicine Of The National Academies. Includes Bibliographical References. Also Issued Online. Mode Of Access: World Wide Web. Cover......Page 1 Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases: The Short-Term and Long-Term Outcomes......Page 2 Copyright......Page 3 National Academy of Sciences......Page 5 MEMBERS OF THE COMMITTEE......Page 6 REVIEWERS......Page 8 CONTENTS......Page 10 PREFACE: A WALK IN THE WOODS......Page 12 1 INTRODUCTION......Page 22 2 An Overview of Tick-Borne Diseases......Page 28 3 THE SOCIAL CONSTRUCTION AND HUMAN FACE OF TICK-BORNE DISEASE......Page 36 4 Emerging Infections, Tick Biology, and Host–Vector Interactions......Page 46 5 SURVEILLANCE, SPECTRUM, AND BURDEN OF TICK-BORNE DISEASE, AND AT-RISK POPULATIONS......Page 64 6 PATHOGENESIS......Page 94 7 Diagnostics and Diagnosis......Page 116 8 PREVENTION......Page 140 9 CLOSING PANELS......Page 158 REFERENCES......Page 172 A PAPERS COMMISSIONED BY THE COMMITTEE......Page 206 A1 THROUGH A GLASS, DARKLY: THE GLOBAL INCIDENCE OF TICK-BORNE DISEASES......Page 207 A2 GLOBAL ENVIRONMENTAL CHANGE AND TICK-BORNE DISEASE INCIDENCE......Page 249 A3 THE HUMAN DIMENSION OF LYME AND OTHER TICK-BORNE DISEASES: THE PATIENT PERSPECTIVE......Page 272 A4 DIAGNOSIS OF TICK-BORNE DISEASES: BORRELIA BURGDORFERI, BABESIA MICROTI, AND ANAPLASMA PHAGOCYTOPHILUM......Page 292 A5 EHRLICHIOSES, RICKETTSIOSES AND ANAPLASMOSIS IN THE UNITED STATES: CURRENT STATUS AND OPPORTUNITIES FOR NEW VACCINES......Page 319 A6 EMERGING AND RE-EMERGING TICK-BORNE DISEASES: NEW CHALLENGES AT THE INTERFACE OF HUMAN AND ANIMAL HEALTH......Page 347 A7 LYME BORRELIOSIS AND OTHER IXODID TICKBORNE DISEASES – A EUROPEAN PERSPECTIVE......Page 372 A-8 THE TICK MICROBIOME: DIVERSITY, DISTRIBUTION AND INFLUENCE OF THE INTERNAL MICROBIAL COMMUNITY FOR A BLOOD-FEEDING DISEASE VECTOR......Page 398 A9 MANAGING SUSPECTED, ATYPICAL LYME DISEASE IN NON-REFERRAL PRACTICES......Page 420 A10 DISEASE SURVEILLANCE AND CASE DEFINITIONS IN TICK-BORNE DISEASES......Page 431 B FEDERAL FUNDING OF TICK-BORNE DISEASES......Page 452 C SUMMARY OF PUBLIC COMMENT ON AGENDA......Page 460 D WORKSHOP AGENDA......Page 464 E WORKSHOP COMMENT SUMMARY......Page 472 F SPEAKER BIOSKETCHES......Page 476