Congestive heart failure and cardiac transplantation : clinical, pathology, imaging, and molecular profiles

A Historical Overview of Cardiovascular Medicine and Heart Failure -- Physiology of the Normal and Failing Heart -- Molecular Biology of the Normal and Failing Heart -- Pathology of Ischemic Heart Disease -- The Pathology of Cardiomyopathies -- Epidemiology of Heart Failure -- Acute Heart Failure -- Ischemic Cardiomyopathy -- Valvular Cardiomyopathy -- Molecular Mechanism of Sarcomeric Cardiomyopathies -- Right Heart Failure -- Neuromuscular Cardiomyopathies -- Heart Failure with Preserved Ejection Fraction (HFpEF) -- Myocardial Viability and Imaging in the Failing Heart -- Cardiorenal Syndrome and Heart Failure -- Neurohormonal Activation and the Management of Heart Failure -- Remodeling in the Development of Chronic Systolic Heart Failure: Implication for Treatment -- Heart Failure Prevention -- Arrhythmias in Cardiomyopathy -- Peripartum Cardiomyopathy -- Advanced Therapies: Cardiac Resynchronization Therapy for Heart Failure -- Ventricular Assist Devices for Advanced Heart Failure -- Regenerative Mechanisms of the Adult Injured and Failing Heart -- Cell therapy and heart failure -- History of Cardiac Transplantation: Research, Discoveries and Pioneers -- Orthotopic Heart Transplantation: A Surgical Perspective -- Cardiac Transplantation: Immunobiology and Immunotherapy -- Cardiac Transplantation Pathology -- Management of the Post-transplant Cardiac Patient -- Adult Orthotopic Heart Transplantation: Early Complications -- Late Complications Following Heart Transplantation -- Heart Transplantation and Antibody-Mediated Rejection -- Heart and Heart-lung Transplantation in Adults with Congenital Heart Disease -- Cardiac Xenotransplantation.;This book is a comprehensive overview of heart failure and cardiac transplantation and integrates scientific and clinical information about the physiology, pathophysiology, diagnosis, and treatment of this disorder. Organized into five parts, it reviews the history and basic mechanisms of heart failure; etiology of heart failure; heart failure disease progression; advanced therapies for heart failure; and cardiac transplantation. The book presents basic concepts in the physiology, molecular biology, pathology, and epidemiology of the normal and failing heart; known causes of heart failure, such as right heart failure, valvular cardiomyopathy, molecular mechanisms of sarcomeric cardiomyopathies, and neuromuscular cardiomyopathy; cardiorenal syndrome; neurohormonal activation; cardiac resynchronization, ventricular assist devices; regenerative mechanisms; orthotopic heart transplantation; early and late management of the post-transplant patient; heart transplantation and antibody-mediated rejections; heart-lung transplantation; and cardiac xenotransplantation. Featuring contributions from leaders in the fields of heart failure, cardiac transplantation, cardiac pathology, and cardiovascular molecular research, Congestive Heart Failure and Cardiac Transplantation is a valuable compendium for cardiologists, cardiothoracic surgeons, researchers, trainees, and students. Front Matter....Pages i-xvi Front Matter....Pages 1-1 A Historical Overview of Cardiovascular Medicine and Heart Failure....Pages 3-19 Physiology of the Normal and Failing Heart....Pages 21-37 Molecular Biology of the Normal and Failing Heart....Pages 39-57 Pathology of Ischemic Heart Disease....Pages 59-79 The Pathology of Cardiomyopathies....Pages 81-92 Epidemiology of Heart Failure....Pages 93-102 Front Matter....Pages 103-103 Acute Heart Failure....Pages 105-117 Ischemic Cardiomyopathy....Pages 119-133 Valvular Cardiomyopathy....Pages 135-149 Molecular Mechanism of Sarcomeric Cardiomyopathies....Pages 151-160 Right Heart Failure....Pages 161-173 Neuromuscular Cardiomyopathies....Pages 175-196 Heart Failure with Preserved Ejection Fraction (HFpEF)....Pages 197-209 Myocardial Viability and Imaging in the Failing Heart....Pages 211-223 Front Matter....Pages 225-225 Cardiorenal Syndrome and Heart Failure....Pages 227-238 Neurohormonal Activation and the Management of Heart Failure....Pages 239-246 Structural Remodeling in the Development of Chronic Systolic Heart Failure: Implication for Treatment....Pages 247-265 Heart Failure Prevention....Pages 267-284 Arrhythmias in Cardiomyopathy....Pages 285-321 Peripartum Cardiomyopathy....Pages 323-337 Front Matter....Pages 339-339 Advanced Therapies: Cardiac Resynchronization Therapy for Heart Failure....Pages 341-359 Ventricular Assist Devices for Advanced Heart Failure....Pages 361-375 Regenerative Mechanisms of the Adult Injured and Failing Heart....Pages 377-400 Cell Therapy and Heart Failure....Pages 401-413 Front Matter....Pages 415-415 History of Cardiac Transplantation: Research, Discoveries, and Pioneers....Pages 417-429 Orthotopic Heart Transplantation....Pages 431-447 Cardiac Transplantation: Immunobiology and Immunotherapy....Pages 449-467 Cardiac Transplantation Pathology....Pages 469-478 Management of the Posttransplant Cardiac Patient....Pages 479-491 Adult Orthotopic Heart Transplantation: Early Complications....Pages 493-504 Late Complications Following Heart Transplant....Pages 505-515 Heart Transplantation and Antibody-Mediated Rejection....Pages 517-537 Heart and Heart–Lung Transplantation in Adults with Congenital Heart Disease....Pages 539-547 Cardiac Xenotransplantation....Pages 549-562 Back Matter....Pages 563-572