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Now in a fully revised Fourth Edition, Modern Epidemiology remains the gold standard text in this complex and evolving field. This edition continues to provide comprehensive coverage of the principles and methods for the design, analysis, and interpretation of epidemiologic research. Featuring a new format allowing space for margin notes, this edition • Reflects both the conceptual development of this evolving science and the increasing role that epidemiology plays in improving public health and medicine. • Features new coverage of methods such as agent-based modeling, quasi-experimental designs, mediation analysis, and causal modeling. • Updates coverage of methods such as concepts of interaction, bias analysis, and time-varying designs and analysis. • Continues to cover the full breadth of epidemiologic methods and concepts, including epidemiologic measures of occurrence and effect, study designs, validity, precision, statistical interference, field methods, surveillance, ecologic designs, and use of secondary data sources. • Includes data analysis topics such as Bayesian analysis, probabilistic bias analysis, time-to-event analysis, and an extensive overview of modern regression methods including logistic and survival regression, splines, longitudinal and cluster-correlated/hierarchical data analysis, propensity scores and other scoring methods, and marginal structural models. • Summarizes the history, specialized aspects, and future directions of topical areas, including among others social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, psychiatric epidemiology, injury and violence epidemiology, and pharmacoepidemiology. Title 2 Copyright 5 Contents 7 Preface and Acknowledgments 13 Contributors 18 PART I Foundations 25 1 The Scope of Epidemiology 26 2 Causal Inference and Scientific Reasoning 59 3 Formal Causal Models 96 4 Measures of Occurrence 143 5 Measures of Effect and Measures of Association 201 6 Epidemiologic Study Design With Validity and Efficiency Considerations 259 PART II Study Design and Interpretation 343 7 Cohort Studies 344 8 Case-颅Control Studies 389 9 Public Health Surveillance 450 10 Field Methods 540 11 Studies Relying on Secondary Data 570 12 Confounding and Confounders 609 13 Measurement and Measurement Error 668 14 Selection Bias and Generalizability 705 15 Precision and Study Size 744 PART III Data Analysis 815 16 Fundamentals of Epidemiologic Data Analysis 816 17 Introduction to Categorical Statistics 880 18 Stratification and Standardization 917 19 Categorical Analysis of Polytomous Exposures and Outcomes 965 20 Regression Analysis Part I: Model Specification 1019 21 Regression Analysis Part II: Model Fitting and Assessment 1085 22 Time-颅To-颅Event Analysis 1142 23 Introduction to Bayesian Statistics 1209 24 Longitudinal and Cluster-颅Correlated Data Analysis 1251 25 Causal Inference With Time-颅Varying Exposures 1303 26 Analysis of Interaction 1341 27 Mediation Analysis 1430 28 Instrumental Variables and Quasi-颅Experimental Approaches 1483 29 Bias Analysis 1565 30 Ecologic Studies and Analysis 1624 31 Agent-颅Based Modeling 1666 PART IV Special Topics 1707 32 Infectious Disease Epidemiology 1708 33 Reproductive Epidemiology 1799 34 Psychiatric Epidemiology 1871 35 Clinical Epidemiology 1922 36 Molecular Epidemiology 2011 37 Genetic Epidemiology 2042 38 Injury and Violence Epidemiology 2093 39 Social Epidemiology 2136 40 Environmental Epidemiology 2195 41 Occupational Epidemiology 2297 42 Nutritional Epidemiology 2359 43 Pharmacoepidemiology 2434 Index 2482 Now in a fully revised 4th Edition, Modern Epidemiology remains the gold standard text in this complex and evolving field, offering unparalleled, comprehensive coverage of the principles and methods of epidemiologic research. Featuring a new, full-color design, updated models, and a new format allowing space for margin notes, this edition continues to provide authoritative information on the methodologic issues crucial to the wide range of epidemiologic applications in public health and medicine.Please note it seems to be a PDF generated from the digital edition. The layout and pagination is then different than the print edition. "Now in a fully revised 4th Edition, Modern Epidemiology remains the gold standard text in this complex and evolving field, offering unparalleled, comprehensive coverage of the principles and methods of epidemiologic research. Featuring a new, full-color design, updated models, and a new format allowing space for margin notes, this edition continues to provide authoritative information on the methodologic issues crucial to the wide range of epidemiologic applications in public health and medicine." - from the publisher "Now in a fully revised Fourth Edition, Modern Epidemiology remains the gold standard text in this complex and evolving field. This edition continues to provide comprehensive coverage of the principles and methods for the design, analysis, and interpretation of epidemiologic research. It also updates coverage of methods such as concepts of interaction, bias analysis, and time-varying designs and analysis and continues to cover the full breadth of epidemiologic methods and concepts"-- Provided by publisher The thoroughly revised and updated Third Edition of Dr. Rothman's acclaimed Modern Epidemiology reflects the conceptual development of this evolving science and the engagement of epidemiologists with an increasing range of current public health concerns