Concepts and Trends in Healthcare Information Systems (Annals of Information Systems Book 16)

Concepts and Trends in Healthcare Information Systems covers the latest research topics in the field from leading researchers and practitioners. This book offers theory-driven research that explores the role of Information Systems in the delivery of healthcare in its diverse organizational and regulatory settings. In addition to the embedded role of Information Technology (IT) in clinical and diagnostics equipment, Information Systems are uniquely positioned to capture, store, process, and communicate timely information to decision makers for better coordination of healthcare at both the individual and population levels. For example, data mining and decision support capabilities can identify potential adverse events for an individual patient while also contributing to the population?s health by providing insights into the causes of disease complications. Information systems have great potential to reduce healthcare costs and improve outcomes. The healthcare delivery systems share similar characteristics with most service and productive organizations, but also exhibit specific characteristics, which are related to the complexity and diversity of healthcare production, including the dissimilar ways healthcare professionals discharge their clinical tasks. New requirements and technological advances occurring in healthcare, information systems, and information technology have influenced the evolving role of healthcare information systems and related technology, and this book will help bring the field up to date. The topics covered include computer based simulation and modeling for healthcare treatment, training, and optimization, role of healthcare information systems in improving care in different national health systems, role of healthcare information systems in fostering improved health and healthier lifestyles, challenges and impact of data standards on healthcare delivery, role of information technology in evidence-based medicine, information systems in personalized medicine, e-health Policy, privacy, security and trust issues with e-health solutions, mobile healthcare initiatives and social media in healthcare Preface 6 Contents 8 Contributors 10 Chapter-1 13 Patient-Generated EHR Input System Trials: An Analysis of Perceived Benefits Across a Range of Disea 13 1.1 Background 14 1.2 Objective 14 1.3 Methods 15 1.4 Results 15 1.5 Conclusion 18 References 19 Chapter-2 20 Utilizing Semantic Web Technologies in Healthcare 20 2.1 Introduction 20 2.2 Semantic Web and Ontologies 21 2.3 Main Biomedical Ontologies 22 2.3.1 Foundational Model of Anatomy (FMA) 22 2.3.2 International Classification of Diseases (ICD-10) 22 2.3.3 Radiological Lexicon (RadLex) 23 2.3.4 Systemized Nomeclature of Medicine-Clinical Terms (SNOMED-CT) 24 2.3.5 Unified Medical Lexicon System (UMLS) 24 2.3.6 Open Biomedical Ontologies (OBO) 25 2.4 Semantic Web Technologies and Ontologies in Healthcare 26 2.4.1 Ontology Based Integration of Heterogeneous Biomedical Data 26 2.4.2 Ontologies and HIS 27 2.5 Use of Ontologies in Biomedical Research 28 2.6 Conclusions 28 References 29 Chapter-3 31 Exploiting Ontology Based Search and EHR Interoperability to Facilitate Clinical Trial Design 31 3.1 Introduction 31 3.1.1 Clinical Research and Clinical Trials 31 3.1.2 Pharmaceutical Clinical Development Alone is a Lengthy and Costly Process 32 3.1.3 Drug Repositioning 34 3.2 Needs and Challenges in the field of Clinical Research 34 3.2.1 Formulating the Research question 35 3.3 Patient Safety 36 3.3.1 Patient Selection 37 3.4 Combining Ontology-based Search and EHRs for Clinical Trial Designs 39 3.4.1 Semantic Searching in Literature 40 3.4.2 Eligibility Criteria and (Research focused) EHR Models 42 3.4.3 Eligibility Criteria Language 43 3.4.4 Translation of Eligibility Criteria into requests towards EHR 44 3.5 Demonstration of the PONTE functionalities 46 3.6 Conclusions and Future Directions 46 References 51 Chapter-4 53 Ontology-Driven Authorization Policies on Personal Health Records for Sustainable Citizen-Centered Healthcare 53 4.1 Introduction 54 4.2 Related Work 55 4.3 The Virtual PHR Concept 57 4.4 The Virtual PHR Service 58 4.5 Virtual PHR Authorization Requirements 59 4.6 Authorization Policy Based on the RABAC Model 60 4.7 Authorization System Architecture 61 4.7.1 Knowledge Repository 62 4.7.2 Authorization Policy Administration 64 4.7.3 Authorization Enforcement Mechanism 65 4.8 Prototype Implementation 65 4.8.1 System Functionality 66 4.9 Concluding Remarks 67 4.10 Future Research Directions 68 References 68 Chapter-5 71 Privacy-Preserving Access Control for PHR-Based Emergency Medical Systems 71 5.1 Introduction 72 5.2 Motivating Scenario 73 5.3 A PHR-Based Emergency System Architecture 75 5.4 Authorization Architecture 77 5.4.1 Authorization Model 77 5.4.2 Authorization System 80 5.5 Implementation Issues 83 5.6 Results and Discussion 86 5.7 Concluding Remarks 87 References 87 Chapter-6 89 Monitoring Patients in a Comorbid Condition with the Aid of Computerized Decision Support System 89 6.1 Introduction 89 6.1.1 Clinical Guideline 90 6.1.2 ECG Features to Diagnose WPW and AF 90 6.1.3 Sources of ECG Noise and Methods of Denoising ECG Signals 92 6.1.4 Related Work on Monitoring Patients in a Comorbid Condition 93 6.2 Design of Monitoring System 94 6.3 Design of Decision Support System in the Patient Device 96 6.3.1 Translate Clinical Guidelines into Logic Expressions 97 6.3.2 Establish a Constraint Logic Programming Model 98 6.3.3 Implement a CLP Model on the ECLiPSe Platform 99 6.4 Analysis on System Performance 100 6.4.1 System Accuracy Analysis 100 6.4.2 Conflict-Detecting Ability of Our System 103 6.4.3 Distribution of ECG Parameters 104 6.5 Simulation and Results 105 6.6 Conclusion 110 References 110 Chapter-7 112 Critical Success Factors in the Implementation of Integrated Healthcare Information Systems 112 7.1 Introduction 112 7.2 Methods 113 7.2.1 Selections, Data Collection and Analysis of CSFs 113 7.2.2 Quantification 115 7.2.3 Hierarchical Decomposition 115 7.2.4 Pairwise Comparison 116 7.2.5 Monitoring 116 7.3 Results 116 7.4 Conclusion 127 References 127 Chapter-8 129 A Preventive Adverse Drug Events System 129 8.1 Introduction 129 8.2 Prevent ADE Systems 130 8.3 ADE Ontology 132 8.4 Ontology Based DataBase 132 8.5 Experiments and Results 137 8.6 Conclusion 138 References 139 Chapter-9 142 Computational Modeling and Simulations in Life Sciences 142 9.1 Introduction 143 9.2 Computational Models for Medical Image Analysis 143 9.3 Computational Models for Image Guided, Robot- Assisted and Simulated Medical Interventions 144 9.4 Computational Disease Models 145 9.5 Computational Modeling of Tumor Response to Vascular-Targeting Therapies 145 9.6 Breast Tumor Simulation and Parameters Estimation Using Evolutionary Algorithms 147 References 147 Chapter-10 149 Stent Deployment Computer Based Simulations for Health Care Treatment of Diseased Arteries 149 10.1 Introduction 150 10.2 The Pathology of the Cardiovascular Disease 150 10.2.1 Cardiovascular Disease 150 10.2.2 Atherosclerosis 151 10.2.3 Treatment Options 152 10.2.4 Coronary Artery Stenting 153 10.3 Stent 153 10.4 Computational Simulation Using the Finite Element Method (FEM) 154 10.4.1 Pre-Processing 155 10.4.2 Analysis Solver 155 10.4.3 Post-Processing 156 10.5 Computational Modeling of Stent Deployment 156 10.5.1 Arterial Models 157 10.5.2 Loading Scenarios 161 10.5.3 Stent Design 161 10.5.4 Plaque Composition 162 10.5.5 Stent Materials 164 10.5.6 Our Approach 164 10.6 Conclusions—Future Work 170 References 170 Chapter-11 174 Development of Collaborative Modular Assembly Micro-Robot Colonies for Use in Natural Orifice Transluminal Endoscopic Surgery: The LABYRINTH Approach 174 11.1 Introduction 175 11.2 The da Vinci Surgical System 176 11.3 Natural Orifice Transluminal Endoscopic Surgery (NOTES) 177 11.4 Notes Micro-Robots 180 11.4.1 In Vivo Fixed Base Camera Micro Robots 181 11.4.2 In Vivo Mobile Camera Micro-Robots 181 11.4.3 In Vivo Mobile Biopsy Micro-Robots 182 11.4.4 In Vivo Endoluminal Mobile Micro-Robots 182 11.4.5 In Vivo Cooperation Micro-Robots 183 11.4.6 In Vivo Dexterous Micro-Robots 183 11.5 Nanorobotics 184 11.5.1 DNA Based Nanorobots 185 11.5.2 Applications of Nanorobots in Disease Diagnosis 185 11.5.3 Treatment of Artery Occlusion 185 11.5.4 Nanorobots in Cancer Detection and Treatment 186 11.5.5 Nanorobotics Control in Brain Aneurysms 186 11.6 Research Experiments 186 11.6.1 Direct Nano-Injection into Cell 186 11.6.2 Nano Knife for Single Cell Cutting 187 11.7 Labyrinth 188 11.7.1 Aim 188 11.7.2 Methods 189 11.7.3 Overview and Initial Specifications of the MINOS-MR Modules and the MINOS-MR 189 11.7.4 In-Silico, Design, Development, Experimentation and Evaluation 193 11.7.5 Operation Modes 193 11.7.6 Potential Impact 194 11.8 Conclusion 194 References 195 Chapter-12 199 Impacts of Robotic Assisted Surgery on Hospital’s Strategic Plan: A Social Cost Approach 199 12.1 Introduction 200 12.2 Experimental 201 12.3 Social Cost Definition 202 12.4 Theory 204 12.5 Results and Discussion 206 12.6 Conclusions 207 References 207 Chapter-13 209 Feature Analysis of Blind Watermarked Electromyogram Signal in Wireless Telemonitoring 209 13.1 Introduction 210 13.2 Methodology 212 13.2.1 Stationary Wavelet Transformation 212 13.2.2 Signal De-noising 213 13.3 Proposed Method 213 13.4 Results and Discussion 218 13.5 Conclusion 229 References 232 Index 234 Concepts and Trends in Healthcare Information Systems covers the latest research topics in the field from leading researchers and practitioners. This book offers theory-driven research that explores the role of Information Systems in the delivery of healthcare in its diverse organizational and regulatory settings. In addition to the embedded role of Information Technology (IT) in clinical and diagnostics equipment, Information Systems are uniquely positioned to capture, store, process, and communicate timely information to decision makers for better coordination of healthcare at both the individual and population levels. For example, data mining and decision support capabilities can identify potential adverse events for an individual patient while also contributing to the populations health by providing insights into the causes of disease complications. Information systems have great potential to reduce healthcare costs and improve outcomes. The healthcare delivery systems share similar characteristics with most service and productive organizations, but also exhibit specific characteristics, which are related to the complexity and diversity of healthcare production, including the dissimilar ways healthcare professionals discharge their clinical tasks. New requirements and technological advances occurring in healthcare, information systems, and information technology have influenced the evolving role of healthcare information systems and related technology, and this book will help bring the field up to date. The topics covered include computer based simulation and modeling for healthcare treatment, training, and optimization, role of healthcare information systems in improving care in different national health systems, role of healthcare information systems in fostering improved health and healthier lifestyles, challenges and impact of data standards on healthcare delivery, role of information technology in evidence-based medicine, information systems in personali zed medicine, e-health Policy, privacy, security and trust issues with e-health solutions, mobile healthcare initiatives and social media in healthcare Front Matter....Pages i-xi Patient-Generated EHR Input System Trials: An Analysis of Perceived Benefits Across a Range of Disease Groups....Pages 1-7 Utilizing Semantic Web Technologies in Healthcare....Pages 9-19 Exploiting Ontology Based Search and EHR Interoperability to Facilitate Clinical Trial Design....Pages 21-42 Ontology-Driven Authorization Policies on Personal Health Records for Sustainable Citizen-Centered Healthcare....Pages 43-60 Privacy-Preserving Access Control for PHR-Based Emergency Medical Systems....Pages 61-78 Monitoring Patients in a Comorbid Condition with the Aid of Computerized Decision Support System....Pages 79-101 Critical Success Factors in the Implementation of Integrated Healthcare Information Systems....Pages 103-119 A Preventive Adverse Drug Events System....Pages 121-133 Computational Modeling and Simulations in Life Sciences....Pages 135-141 Stent Deployment Computer Based Simulations for Health Care Treatment of Diseased Arteries....Pages 143-167 Development of Collaborative Modular Assembly Micro-Robot Colonies for Use in Natural Orifice Transluminal Endoscopic Surgery: The LABYRINTH Approach....Pages 169-193 Impacts of Robotic Assisted Surgery on Hospital’s Strategic Plan: A Social Cost Approach....Pages 195-204 Feature Analysis of Blind Watermarked Electromyogram Signal in Wireless Telemonitoring....Pages 205-229 Back Matter....Pages 231-235