Computational Intelligence Methods for Bioinformatics and Biostatistics : 13th International Meeting, CIBB 2016, Stirling, UK, September 1-3, 2016, Revised Selected Papers

This book constitutes the thoroughly refereed post-conference proceedings of the 13th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2016, held in Stirling, UK, in September 2016. The 19 revised full papers and 6 keynotes abstracts presented were carefully reviewed and selected from 61 submissions. The papers deal with the application of computational intelligence to open problems in bioinformatics, biostatistics, systems and synthetic biology, medicalinformatics, computational approaches to life sciences in general Front Matter ....Pages I-XXII Module Detection Based on Significant Shortest Paths for the Characterization of Gene Expression Data (Daniele Pepe)....Pages 1-11 Information-Theoretic Active Contour Model for Microscopy Image Segmentation Using Texture (Veronica Biga, Daniel Coca)....Pages 12-26 Host Phenotype Prediction from Differentially Abundant Microbes Using RoDEO (Anna Paola Carrieri, Niina Haiminen, Laxmi Parida)....Pages 27-41 DeepScope: Nonintrusive Whole Slide Saliency Annotation and Prediction from Pathologists at the Microscope (Andrew J. Schaumberg, S. Joseph Sirintrapun, Hikmat A. Al-Ahmadie, Peter J. Schüffler, Thomas J. Fuchs)....Pages 42-58 PLS-SEM Mediation Analysis of Gene-Expression Data for the Evaluation of a Drug Effect (Daniele Pepe, Tomasz Burzykowski)....Pages 59-69 A Novel Algorithm for CpG Island Detection in Human Genome Based on Clustering and Chaotic Particle Swarm Optimization (Abdelbasset Boukelia, Zakaria Benmounah, Mohamed Batouche, Bouchera Maati, Ikram Nekkache)....Pages 70-81 COSYS: A Computational Infrastructure for Systems Biology (Fabio Cumbo, Marco S. Nobile, Chiara Damiani, Riccardo Colombo, Giancarlo Mauri, Paolo Cazzaniga)....Pages 82-92 Statistical Texture-Based Mapping of Cell Differentiation Under Microfluidic Flow (Veronica Biga, Olívia M. Alves Coelho, Paul J. Gokhale, James E. Mason, Eduardo M. A. M. Mendes, Peter W. Andrews et al.)....Pages 93-106 Constraining Mechanism Based Simulations to Identify Ensembles of Parametrizations to Characterize Metabolic Features (Riccardo Colombo, Chiara Damiani, Giancarlo Mauri, Dario Pescini)....Pages 107-117 Process Algebra with Layers: Multi-scale Integration Modelling Applied to Cancer Therapy (Erin Scott, James Nicol, Jonathan Coulter, Andrew Hoyle, Carron Shankland)....Pages 118-133 A Problem-Driven Approach for Building a Bioinformatics GraphDB (Antonino Fiannaca, Massimo La Rosa, Laura La Paglia, Antonio Messina, Riccardo Rizzo, Alfonso Urso)....Pages 134-144 Parameter Inference in Differential Equation Models of Biopathways Using Time Warped Gradient Matching (Mu Niu, Simon Rogers, Maurizio Filippone, Dirk Husmeier)....Pages 145-159 IRIS-TCGA: An Information Retrieval and Integration System for Genomic Data of Cancer (Fabio Cumbo, Emanuel Weitschek, Paola Bertolazzi, Giovanni Felici)....Pages 160-171 Effect of UV Radiation on DPPG and DMPC Liposomes in Presence of Catechin Molecules (Filipa Pires, Gonçalo Magalhães-Mota, Paulo António Ribeiro, Maria Raposo)....Pages 172-183 Inference in a Partial Differential Equations Model of Pulmonary Arterial and Venous Blood Circulation Using Statistical Emulation (Umberto Noè, Weiwei Chen, Maurizio Filippone, Nicholas Hill, Dirk Husmeier)....Pages 184-198 Ensemble Approaches for Stable Assessment of Clusters in Microbiome Samples (Sanja Brdar, Vladimir Crnojević)....Pages 199-208 Multilayer Data and Document Stratification for Comorbidity Analysis (Kevin Heffernan, Pietro Liò, Simone Teufel)....Pages 209-219 Evolving Dendritic Morphologies Highlight the Impact of Structured Synaptic Inputs on Neuronal Performance (Mohammad Ziyad Kagdi)....Pages 220-234 Semantic Clustering for Identifying Overlapping Biological Communities (Hassan Mahmoud, Francesco Masulli, Stefano Rovetta)....Pages 235-247 Back Matter ....Pages 249-249