Computational Bioengineering

Computational bioengineering takes advantage of the latest computational capabilities to deal with scientific and engineering problems associated with the field of bioengineering, using a multidisciplinary approach. The first book of its kind, this book introduces readers to the need and power of multidisciplinary computer modeling to advance a number of critical areas within bioengineering. It contains comprehensive coverage of the interplay of multiple governing principles underlying common biomedical devices and problems. Many of the contributors will be world class experts and appropriate case studies will be included. Front Cover 1 Contents 7 Preface 9 Editor 11 Contributors 13 Chapter 1: An Integrative Way of Solving Bioengineering Problems 15 Chapter 2: Toward Predicting the Performance of Joint Arthroplasty 23 Chapter 3: Mathematical Modelling of Basic Multicellular Units: The Functional Units of Bone Remodeling 59 Chapter 4: Effect of Nonlinearity in Tensioned Wires of an External Fixation Device 89 Chapter 5: Viscoelasticity of Load-Bearing Soft Tissues: Constitutive Formulation, Numerical Integration, and Computational Implementation 109 Chapter 6: Physical Signals and Solute Transport in Human Intervertebral Disc: Multiphasic Mechano-Electrochemical Finite Element Analysis 137 Chapter 7: Multiscale Modeling of Cardiovascular Flows 177 Chapter 8: Computational Fluid Modeling of Heart Valves 205 Chapter 9: Mathematical Modeling of Cancer Metastases 225 Chapter 10: Dynamic Processes in Photodynamic Therapy 245 Chapter 11: Computational Cell Phenotyping in the Lab, Plant, and Clinic 279 Chapter 12: Molecular Simulation of Protein–Surface Interactions 307 Chapter 13: Structure of the Electrical Double Layers: Insights from Continuum and Atomistic Simulations 341 Chapter 14: A Solid-State Nanopore as Biosensor 369 Chapter 15: DNA Electrokinetic Translocation through a Nanopore 391 Chapter 16: Dielectrophoresis for Bioengineering Applications and Some Associated Issues 415 Chapter 17: Image-Based Modeling for Bioengineering Problems 439 Back Cover 479 Arguably the first book of its kind, Computational Bioengineering explores the power of multidisciplinary computer modeling in bioengineering. Written by experts, the book examines the interplay of multiple governing principles underlying common biomedical devices and problems, bolstered by case studies. It shows you how to take advantage of the la