Codice appalti dlgs 36 2023 con note e allegati

"Clear writing and illustrations ... Clear explanations of difficult concepts ... Clear communication of the ways in biochemistry is currently understood and practiced. For over 35 years, in edition after bestselling edition, Principles of Biochemistry has put those defining principles into practice, guiding students through a coherent introduction to the essentials of biochemistry without overwhelming them. The new edition brings this remarkable text into a new era. Like its predecessors, Lehninger Principles of Biochemistry, Sixth Edition strikes a careful balance of current science and enduring concepts, incorporating a tremendous amount of new findings, but only those that help illustrate biochemistry's foundational principles. With this edition, students will encounter new information emerging from high throughput DNA sequencing, x-ray crystallography, and the manipulation of genes and gene expression, and other techniques. In addition, students will see how contemporary biochemistry has shifted away from exploring metabolic pathways in isolation to focusing on interactions among pathways. They will also get an updated understanding of the relevance of biochemistry to the study of human disease (especially diabetes) as well as the important role of evolutionary theory in biochemical research. These extensive content changes, as well as new art and powerful new learning technologies make this edition of Lehninger Principles of Biochemistry the most impressive yet." --Publisher description "Clear writing and illustrations... Clear explanations of difficult concepts... Clear communication of the ways in biochemistry is currently understood and practiced. For over 35 years, in edition after bestselling edition, Principles of Biochemistry has put those defining principles into practice, guiding students through a coherent introduction to the essentials of biochemistry without overwhelming them. The new edition brings this remarkable text into a new era. Like its predecessors, Lehninger Principles of Biochemistry, Sixth Edition strikes a careful balance of current science and enduring concepts, incorporating a tremendous amount of new findings, but only those that help illustrate biochemistry's foundational principles. With this edition, students will encounter new information emerging from high throughput DNA sequencing, x-ray crystallography, and the manipulation of genes and gene expression, and other techniques. In addition, students will see how contemporary biochemistry has shifted away from exploring metabolic pathways in isolation to focusing on interactions among pathways. They will also get an updated understanding of the relevance of biochemistry to the study of human disease (especially diabetes) as well as the important role of evolutionary theory in biochemical research. These extensive content changes, as well as new art and powerful new learning technologies make this edition of Lehninger Principles of Biochemistry the most impressive yet."-- Résumé de l'éditeur Preface vi 1 The Foundations of Biochemistry 1 I STRUCTURE AND CATALYSIS 45 2 Water 47 3 Amino Acids, Peptides, and Proteins 75 4 The Three-Dimensional Structure of Proteins 115 5 Protein Function 157 6 Enzymes 189 7 Carbohydrates and Glycobiology 243 8 Nucleotides and Nucleic Acids 281 9 DNA-Based Information Technologies 313 10 Lipids 357 11 Biological Membranes and Transport 385 12 Biosignaling 433 II BIOENERGETICS AND METABOLISM 501 13 Bioenergetics and Biochemical Reaction Types 505 14 Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway 543 15 Principles of Metabolic Regulation 587 16 The Citric Acid Cycle 633 17 Fatty Acid Catabolism 667 18 Amino Acid Oxidation and the Production of Urea 695 19 Oxidative Phosphorylation and Photophosphorylation 731 20 Carbohydrate Biosynthesis in Plants and Bacteria 799 21 Lipid Biosynthesis 833 22 Biosynthesis of Amino Acids, Nucleotides, and Related Molecules 881 23 Hormonal Regulation and Integration of Mammalian Metabolism 929 III INFORMATION PATHWAYS 977 24 Genes and Chromosomes 979 25 DNA Metabolism 1009 26 RNA Metabolism 1057 27 Protein Metabolism 1103 28 Regulation of Gene Expression 1155 Abbreviated Solutions to Problems AS-1 Glossary G-1 Credits C-1 Index I-1
Authors Dave Nelson and Mike Cox combine the best of the laboratory and best of the classroom, introducing exciting new developments while communicating basic principles of biochemistry.