CNS Injuries: Cellular Responses and Pharmacological Strategies (Pharmacology & Toxicology (CRC Pr))

The basic science of the cellular and molecular responses of the brain to injury is a rapidly expanding area of research that provides evidence of growing opportunities for pharmacological intervention in the clinic. CNS Injuries: Cellular Responses and Pharmacological Strategies is an up-to-date examination of new developments in our understanding of the cellular and trophic responses to CNS injuries and the potential treatment. This text collates reviews of the most important areas of study regarding injury response including oinflammatory and immune reactionsoscarringoneuron deathodemyelination and remyelinationoaxonal regenerationore-establishment of neuronal connectivityProviding a record of recent advances that will help point the way to future developments, this enlightening reference is sure to benefit researchers and practitioners in a broad range of disciplines, including: neurology, pharmacology, pathology, toxicology, immunology, and many others. The basic science of the cellular and molecular responses of the brain to injury is a rapidly expanding area of research that provides evidence of growing opportunities for pharmacological intervention in the clinic. CNS Injuries: Cellular Responses and Pharmacological Strategies is an up-to-date examination of new developments in our understanding of the cellular and trophic responses to CNS injuries and the potential treatment. This text collates reviews of the most important areas of study regarding injury response including

• inflammatory and immune reactions
  
• scarring
  
• neuron death
  
• demyelination and remyelination
  
• axonal regeneration
  
• re-establishment of neuronal connectivity Providing a record of recent advances that will help point the way to future developments, this enlightening reference is sure to benefit researchers and practitioners in a broad range of disciplines, including: neurology, pharmacology, pathology, toxicology, immunology, and many others.

The book contains black-and-white illustrations.

Three distinct sequential cellular responses characterise the reaction of the adult spinal cord and brain to injury.