Clinical Manual of Psychopharmacology in the Medically Ill, Third Edition

With examinations of 19 new psychiatric drugs, 19 new forms of previously available drugs, and a host of new medical agents, this third edition of the Clinical Manual of Psychopharmacology in the Medically Ill has been updated to include medical and psychiatric drugs that have become available since the publication of the second edition in 2017, as well as recent relevant randomized controlled trials, systematic reviews, and meta-analyses. Boasting all the rigor that characterized the preceding editions, every chapter in this new volume has been reviewed and revised by experts—including 11 new authors. For 15 categories of medical disorders and specialty areas that include cardiovascular disorders, oncology, obstetrics and gynecology, and substance use disorders, the book examines Key differential diagnostic considerations The evidence for the efficacy of psychiatric drugs in each disorder Disease-specific side effects of psychiatric drugs Neuropsychiatric side effects of drugs for each medical disorder Disease-specific alterations in pharmacokinetics Drug-drug interactions Patients with medical and psychiatric comorbidity have more functional impairment, disability days, emergency department use, and rehospitalization, as well as higher medical care costs. By examining the intersection of psychiatric and medical illness, and offering easily referenced key points for each chapter, this new edition prepares both mental health practitioners and primary care physicians and internists to more safely and effectively work with patients who have psychiatric and medical illness. Cover Half Title Title Copyright Contents Contributors Acknowledgments Introduction Part 1 General Principles 1 Pharmacokinetics, Pharmacodynamics, and Principles of Drug-Drug Interactions Pharmacodynamics Pharmacokinetics Drug-Drug Interactions Appendix A: Psychotropic Drugs With Clinically Significant Pharmacokinetic Interactions Appendix B: Select List of Medications, Foods, and Herbals With Clinically Significant Pharmacokinetic Interactions Appendix C: Some Websites With Drug-Drug Interaction Checking Software 2 Severe Drug Reactions Central Nervous System Drug Reactions Cardiovascular Drug Reactions Gastrointestinal Drug Reactions Renal Drug Reactions Hematological Drug Reactions Metabolic Drug Reactions and Body as a Whole 3 Alternative Routes of Drug Administration Properties of Specific Routes of Administration Psychotropic Medications Conclusion Part 2 Psychopharmacology in Organ System Disorders and Specialty Areas 4 Gastrointestinal Disorders Oropharyngeal Disorders Esophageal and Gastric Disorders Intestinal Disorders Liver Disorders Gastrointestinal Side Effects of Psychiatric Drugs Psychotropic Drug–Induced Gastrointestinal Complications Psychiatric Side Effects of Gastrointestinal Medications Drug-Drug Interactions Conclusion 5 Renal and Urological Disorders Differential Diagnosis Pharmacotherapy in Renal Disease Psychiatric Adverse Effects of Renal and Urological Agents Renal and Urological Adverse Effects of Psychotropics Drug-Drug Interactions 6 Cardiovascular Disorders Differential Diagnostic Considerations Neuropsychiatric Side Effects of Cardiovascular Medications Pharmacokinetic Alterations in Heart Disease Psychotropic Medication Use in Heart Disease Drug-Drug Interactions 7 Respiratory Disorders Differential Diagnostic Considerations Neuropsychiatric Side Effects of Drugs Used to Treat Respiratory Diseases Alteration of Pharmacokinetics Effects of Psychotropic Drugs on Pulmonary Function Prescribing Psychotropic Medications in Respiratory Disease Drug-Drug Interactions 8 Oncology Differential Diagnosis of Psychiatric Manifestations of Cancers Psychopharmacological Treatment of Psychiatric Disorders in Patients With Cancer Adverse Oncological Effects of Psychotropics Neuropsychiatric Adverse Effects of Oncology Treatments Drug-Drug Interactions 9 Central Nervous System Disorders Dementia Stroke Traumatic Brain Injury Multiple Sclerosis Parkinson's Disease Huntington's Disease Epilepsy Symptoms and Syndromes Common Across Neurological Disorders Adverse Neurological Effects of Psychotropic Medications Adverse Psychiatric Effects of Neurological Medications Drug-Drug Interactions 10 Endocrine and Metabolic Disorders Diabetes Mellitus Thyroid Disorders Pheochromocytoma Antidiuretic Hormone Reproductive Endocrine System Disorders Hypogonadal Disorders Endocrinological Side Effects of Psychiatric Medications Psychiatric Side Effects of Endocrine Treatments Drug-Drug Interactions 11 Obstetrics and Gynecology Differential Diagnosis Pharmacotherapy for Premenstrual Mood Symptoms Pharmacotherapy for Menopause-Related Depression, Anxiety, and Insomnia Psychopharmacology During Pregnancy and Breastfeeding Adverse Obstetrical and Gynecological Reactions to Psychotropic Drugs Psychiatric Effects of Obstetrical and Gynecological Agents and Procedures Drug-Drug Interactions 12 Infectious Diseases Bacterial Infections Viral Infections: HIV/AIDS Viral Infections Other Than HIV Parasitic Infections: Neurocysticercosis Adverse Psychiatric Effects of Antibiotics Drug-Drug Interactions 13 Dermatological Disorders Classification Pharmacotherapy for Dermatological Symptoms of Psychiatric Disorders Adverse Cutaneous Drug Reactions to Psychotropic Agents Adverse Psychiatric Effects of Dermatological Agents Drug-Drug Interactions 14 Rheumatological Disorders Treatment of Psychiatric Disorders Psychiatric Side Effects of Rheumatological Medications Rheumatological Side Effects of Psychotropic Medications: Psychotropic Drug– Induced Lupus Drug-Drug Interactions 15 Critical Care and Surgery Delirium Catatonia Acute and Posttraumatic Stress in the Critical Care Setting Psychotropic Drugs in the Perioperative Period Treatment of Preoperative Anxiety Adverse Neuropsychiatric Effects of Critical Care and Surgical Drugs Drug-Drug Interactions 16 Organ Transplantation Posttransplant Pharmacological Considerations Psychotropic Medications in Transplant Recipients Drug-Specific Issues Conclusion 17 Pain Management Psychiatric Comorbidity Pain Description and Management Pain Plus Depression Pharmacological Treatment Drug-Drug Interactions 18 Substance Use Disorders Substance Intoxication Substance Use Disorders Neuropsychiatric Adverse Effects of Drugs Used for Substance-Related Disorders Drug-Drug Interactions Index Back Cover