Clinical Hepatology : Principles and Practice of Hepatobiliary Diseases: Volume 1

Clinical Hepatology - Principles and Practice of Hepatobiliary Diseases provides clear and comprehensive coverage of the etiology, mechanisms of disease, diagnosis, and practical management of the entire spectrum of liver and biliary disorders. It also affords an excellent, evidence-based review of the rapidly expanding field of hepatobiliary diseases. Comprehensive Very readable Practical Up to date Provides a rational basis for the practice of hepatology Your one-step resource for clinical hepatology Fast and easy access to common and rare problems encountered in practice Henryk Dancygier is Chief of the Department of Medicine II at the Klinikum Offenbach, and Professor of Medicine at the Goethe University, Frankfurt/Main. He graduated from the University of Heidelberg and trained in Pathology, Internal Medicine, Gastroenterology and Hepatology. He holds degrees from the University of Heidelberg, Frankfurt and the Technical University of Munich and currently is Adjunct Professor of Medicine at the Mount Sinai School of Medicine, New York. Henryk Dancygier is author of a number of books including (English translations) "AIDS - a Clinical Compendium" (1993), "Memorix - Gastroenterology and Hepatology" (1998), "Endosonography in Gastroeneterology: Principles, Techniques, Findings" (1999), "Liver Diseases - the ABC of Therapy" (2003) and "Clinical Hepatology - Diagnosis and Therapy of Hepatobiliary Disorders" (2003) that have been translated into several languages and he has also contributed numerous chapters in Medical Textbooks. Front Matter....Pages i-xxviii Embryonic Development....Pages 7-10 Gross Anatomy....Pages 11-14 Microscopic Anatomy....Pages 15-51 Hepatic Circulation....Pages 55-59 Hepatocellular Transport....Pages 61-74 Hepatic Metabolism....Pages 75-102 Formation and Secretion of Bile and Bilirubin Metabolism....Pages 103-125 Hepatic Biotransformation....Pages 127-130 Functional Heterogeneity and Metabolic Zonation....Pages 131-136 Liver Cell Hydration and Cell Function....Pages 137-140 The Liver as an Immune Organ....Pages 141-152 Aging and the Liver....Pages 153-156 Hepatic Regeneration....Pages 157-168 Free Radicals, Reactive Oxygen Species, Oxidative and Endoplasmic Reticulum Stress....Pages 173-180 Hypoxic Liver Injury....Pages 181-183 Reperfusion Injury....Pages 185-187 Drug-Induced and Toxic Liver Injury....Pages 189-190 Immune Mediated Liver Injury....Pages 191-196 Endotoxin Mediated Liver Injury....Pages 197-198 Cholestasis-Induced Liver Injury....Pages 199-200 Metal-Induced Liver Injury....Pages 201-202 Radiation-Induced Liver Damage....Pages 203-204 Liver Cell Degeneration and Cell Death....Pages 207-218 Cellular Adaptation, Intracellular Inclusions and Deposits....Pages 219-234 Necroinflammatory Reaction....Pages 235-239 Cholestatic Reaction....Pages 241-246 Granulomatous Reaction....Pages 247-249 Fibrogenic Reaction....Pages 251-268 Histopathological Scoring Systems....Pages 271-288 Clinical Scoring Systems....Pages 289-293 History....Pages 301-303 Symptoms....Pages 305-307 Physical Examination....Pages 309-316 Basic Laboratory Parameters....Pages 319-331 Tests of Liver Function....Pages 333-343 Autoantibodies....Pages 345-355 Ultrasonography....Pages 359-404 Computed Tomography and Magnetic Resonance Imaging....Pages 405-423 Nuclear Imaging....Pages 425-436 Endoscopic Retrograde and Percutaneous Transhepatic Cholangiography....Pages 437-447 Cholangioscopy....Pages 449-454 Endoscopic Ultrasonography....Pages 455-461 Percutaneous Liver Biopsy....Pages 463-472 Transvenous Liver Biopsy....Pages 473-484 Laparoscopy....Pages 485-510 Measurement of Portal Pressure....Pages 511-517 Sphincter of Oddi Manometry....Pages 519-523 Approach to the Patient with Upper Abdominal Pain....Pages 527-532 Approach to the Patient with Abnormal Liver Enzymes....Pages 533-547 Approach to the Patient with Hepatomegaly....Pages 549-551 Approach to the Patient with Focal Liver Lesions....Pages 553-557 Approach to the Patient with Cholestasis and Jaundice....Pages 559-592 Approach to the Patient with Portal Hypertension....Pages 593-602 Approach to the Patient with Ascites....Pages 603-614 Back Matter....Pages S1-S38 This title provides clear and comprehensive coverage of the etiology, mechanisms of disease, diagnosis, and practical management of the entire spectrum of liver and biliary disorders. It also affords an excellent, evidence-based review of the rapidly expanding field of hepatobiliary diseases Suitable for internists and further learning specialists, this book presents an overview of the standard of research in hepatology. It provides basic information about morphology and pathophysiology and serves as a reference for various diseases