CLINICAL DIAGNOSIS AND MANAGEMENT OF ALZHEIMER'S DISEASE; ED. BY SERGE GAUTHIER

The third edition of this successful textbook has been completely updated throughout and includes new chapters on electrophysiological tests, biological markers, global staging measures, and management of neuropsychiatric symptoms. There has been steady progress in our understanding of the natural history, prognostic factors and treatments for AlzheimerвЂTMs disease since the previous edition of this textbook was published in 1999. The chapters deal with the full spectrum of populations at risk, persons in prodromal stages, and patients from mild to severe and even terminal stages. The contributors are opinion leaders from North America and Europe, which gives the book an internationally balanced outlook. This new edition will be essential reading for a wide range of clinical neuroscientists who manage patients with this challenging disease. Front cover 2 Contents 7 Contributors 10 Foreword 14 Preface to the Third Edition 16 Other Titles by Serge Gauthier 4 Part I: Introduction to the disease process 17 Chapter 1. Definitions and diagnostic criteria 19 Chapter 2. Pathophysiology: a neurochemical perspective 31 Chapter 3. Pathophysiology: an epidemiological perspective 43 Part II: Diagnosis 53 Chapter 4. Typical clinical features 55 Chapter 5. Differentiation from non-Alzheimer dementia 69 Chapter 6. Neuropsychological assessment 83 Chapter 7. Structural brain imaging 97 Chapter 8. Functional brain imaging 113 Chapter 9. Electrophysiological tests 127 Chapter 10. Biological markers 141 Part III: Natural evolution 151 Chapter 11. Natural decline and prognostic factors 153 Chapter 12. Global assessment measures 165 Chapter 13. Depressive syndrome in Alzheimer's disease 175 Chapter 14. Cognition 181 Chapter 15. Functonal autonomy 193 Chapter 16. Behaviour 205 Part IV: Medical management 219 Chapter 17. Mild cognitive impairment and very early stage Alzheimer's disease 221 Chapter 18. Mild to moderate stages 237 Chapter 19. Care of patients in the severe stage of dementia 249 Chapter 20. Terminal stage 263 Chapter 21. Co-existent medical problems and concomitant diseases 273 Chapter 22. Management of neurophychiatric symptoms 281 Part V: Community and institutional management 293 Chapter 23. Caregiver support: support of families 295 Chapter 24. Community-based formal support services 315 Part VI: Ethical and quality of life issues 329 Chapter 25. Ethical issues 331 Chapter 26. Competency 341 Chapter 27. Genetic counselling 357 Chapter 28. Health-related quality of life measurement techniques in the management of dementia 367 Part VII: Conclusion 393 Chapter 29. Future diagnosis and managemnt of Alzheimer's disease 395 Index 399 Back cover 411 Definitions and diagnostic criteria Pathophysiology: a neurochemical perspective Pathophysiology: an epidemiological perspective Typical clinical features Differentiation from non-Alzheimer dementia Neuropsychological assessment Structural brain imaging Functional brain imaging Electrophysiological tests Biological markers Natural decline and prognostic factors Global assessment measures Depressive syndrome in Alzheimer's disease Cognition Functional autonomy Behaviour Mild cognitive impairment and very early stage Alzheimer's disease Mild to moderate stages Care of patients in the severe stage of dementia Terminal stage Co-existent medical problems and concomitant diseases Management of neuropsychiatric symptoms Caregiver support: support of families Community -based formal support services Ethical issues Competency Genetic counselling Health-related quality of life measurement techniques in the management of dementia Future diagnosis and management of Alzheimer's disease. "The third edition of this successful textbook Clinical Diagnosis and Management of Alzheimer's Disease has been completely updated throughout and includes new chapters on electrophysiological tests, biological markers, global staging measures and management of neuropsychiatric symptoms. There has been steady progress in our understanding of the natural history, prognostic factors and treatments for Alzheimer's disease since the previous edition of this textbook was published in 1999. The chapters deal with the full spectrum of populations at risk, persons in prodromal stages, and patients from mild to severe and even terminal stages. The contributors are opinion leaders from North America and Europe, which gives the book an internationally balanced outlook. This new edition will be essential reading for a wide range of clinical neuroscientists who manage patients with this challenging disease."--[Résumé de l'éditeur] Includes information on electrophysiological tests, biological markers, global staging measures, and management of neuropsychiatric symptoms. This book looks at our understanding of the natural history, prognostic factors and treatments for Alzheimer's disease. It deals with the populations at risk, persons in prodromal stages, and more Alzheimer's disease (AD) is a progressive neurodegenerative disorder with characteristic clinical and pathological features.