Clinical Applications of Biomaterials : State-of-the-Art Progress, Trends, and Novel Approaches

This book examines the most novel and state-of-the-art applications of biomaterials, with chapters that exemplify approaches with targeted drug delivery, diabetes, neurodegenerative diseases and cranioplasty implants. Expert contributors analyze biomaterials such as calcium phosphate, sol-gel and quenched glasses, metallic and polymer implants, bioactive glass, and polymer composites while also covering important areas such as the soft tissue replacement, apatites, bone regeneration and cell encapsulation. This book is appropriate for biomedical engineers, materials scientists, and clinicians who are seeking to implement the most advanced approaches and technologies with their patients. Front Matter....Pages i-xxv How Did Bioactive Glasses Revolutionize Medical Science? A Tribute to Larry Hench....Pages 1-34 Variation in Properties of Bioactive Glasses After Surface Modification....Pages 35-63 Apatites for Orthopedic Applications....Pages 65-90 Calcium Phosphate Cements for Medical Applications....Pages 91-121 Calcium Orthophosphate-Based Bioceramics and Its Clinical Applications....Pages 123-226 Nanostructured Calcium Phosphates for Drug, Gene, DNA and Protein Delivery and as Anticancer Chemotherapeutic Devices....Pages 227-256 Synthesis and Functionalization of Mesoporous Bioactive Glasses for Drug Delivery....Pages 257-286 Bioactive Glass/Polymer Composites for Drug Delivery....Pages 287-311 Restorative Dental Glass-Ceramics: Current Status and Trends....Pages 313-336 Bioactive Glass-Based Composites for Cranioplasty Implants....Pages 337-355 Antibacterial Properties of Bioactive Glasses....Pages 357-382 Development of URISTTM a Multiphasic rhBMP-2 Bone Graft Substitute....Pages 383-410 Development and In Vitro Analysis of a New Biodegradable PLA/Hydroxyapatite (HAp) Composite for Biomedical Applications....Pages 411-423 Biomaterials for Cell Encapsulation: Progress Toward Clinical Applications....Pages 425-458 Back Matter....Pages 459-467