Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic and Nutritional and Deposition Disease

Annotation Through a unique presentation of clinical photographs and accompanying histologic photomicrographs, Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease provides the practicing surgical pathologist, dermatologist, endocrinologist, internal medicine physician and dermatopathologist with a single volume source that reviews the clinical and pathologic features of metabolic and endocrine disorders that display cutaneous manifestations. Color photographs are presented for each condition followed by a series of phoromicrographs depicting each entity microscopically. The text includes Clinical Features, Pathology, Etiopathogenesis, Differential Diagnosis and Therapy for all entities, described in a clear, concise style. In-depth discussions of the clinical findings, as well as the histologic features of these diseases are included. Additionally, laboratory data used to make and support the diagnoses is discussed for each entity. The first section covers metabolic disorders that have cutaneous manifestations. Diseases organized by the endocrine organ primarily responsible for the systemic condition are covered. For each entity, an atlas of clinical manifestations is presented that will serve as a âbed-sideâ clinical reference, followed by a series of photomicrographs depicting the histologic changes. This unique format of presentation is followed throughout the volume in the second through fourth sections addressing Metabolic Diseases, Nutritional Disorders that affect the skin and finally Cutaneous Deposition Disorders. Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease is a unique reference for the practicing dermatopathologist, general pathologist reviewing skin biopsies, general dermatologists, internists and endocrinologists Annotation Through a unique presentation of clinical photographs and accompanying histologic photomicrographs, Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease provides the practicing surgical pathologist, dermatologist, endocrinologist, internal medicine physician and dermatopathologist with a single volume source that reviews the clinical and pathologic features of metabolic and endocrine disorders that display cutaneous manifestations. Color photographs are presented for each condition followed by a series of phoromicrographs depicting each entity microscopically. The text includes Clinical Features, Pathology, Etiopathogenesis, Differential Diagnosis and Therapy for all entities, described in a clear, concise style. In-depth discussions of the clinical findings, as well as the histologic features of these diseases are included. Additionally, laboratory data used to make and support the diagnoses is discussed for each entity. The first section covers metabolic disorders that have cutaneous manifestations. Diseases organized by the endocrine organ primarily responsible for the systemic condition are covered. For each entity, an atlas of clinical manifestations is presented that will serve as a âbed-sideâ clinical reference, followed by a series of photomicrographs depicting the histologic changes. This unique format of presentation is followed throughout the volume in the second through fourth sections addressing Metabolic Diseases, Nutritional Disorders that affect the skin and finally Cutaneous Deposition Disorders. Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease is a unique reference for the practicing dermatopathologist, general pathologist reviewing skin biopsies, general dermatologists, internists and endocrinologists It is a pleasure to introduce this new book, Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional, and Deposition Disease, edited by two of my friends and respected colleagues, Franco Rongioletti and Bruce R. Smoller. In fact, I was very ent- siastic when I learned that they were preparing this work. Although endocrine, metabolic, w, and deposition diseases are regularly included in general textbooks of dermatology and d- matopathology, one gains the general impression that these topics receive little emphasis and are mainly included for completeness. The prospect of having all of this information in one volume, lovingly described and detailed by experts in the feld, should be of great interest not only to dermatologists, pathologists, and dermatopathologists but also to internists and en- crinologists, who may well gain a different perspective on these disorders. As a derma- pathologist, I am also pleased that this project has been organized and undertaken by two distinguished authorities in cutaneous pathology. This assures a close integration of histo- thology and other laboratory techniques with the clinical aspects of these disorders, which will make it possible – perhaps for the frst time – to view these conditions in a truly comprehensive way. So I invite you, the reader, to open this volume and dig in; be prepared for an eye-catching, intellectually stimulating, and ultimately rewarding experience! Charlottesville, VA James W. Patterson v w Foreword II Dermatopathology is a bridge between Dermatology and Pathology. Front Matter....Pages i-xiv Front Matter....Pages 1-1 Adrenal Disease....Pages 3-10 Pancreas Disease and Diabetes Mellitus....Pages 11-25 Thyroid Disease....Pages 27-33 Pituitary Gland Diseases....Pages 35-41 Parathyroid Disease....Pages 43-51 Front Matter....Pages 53-53 Dyslipidemia (Hyperlipidemia)....Pages 55-61 Gout....Pages 63-67 Lipomatosis....Pages 69-73 Obesity....Pages 75-82 Porphyrias....Pages 83-90 Hemochromatosis....Pages 91-93 Metabolic Syndrome in Psoriasis....Pages 95-98 Front Matter....Pages 99-99 Acquired Nutritional Deficiencies....Pages 101-108 Anorexia Nervosa....Pages 109-114 Alcohol Abuse....Pages 115-120 Glucagonoma Syndrome and Necrolytic Migratory Erythema....Pages 121-124 Front Matter....Pages 125-125 Amyloidoses....Pages 127-137 Mucinoses....Pages 139-152 Lipoid Proteinosis....Pages 153-156 Colloid Milium....Pages 157-160 Front Matter....Pages 125-125 Calcification and Ossification....Pages 161-169 Pigmentary Deposition Disorders....Pages 171-180 Exogenous Cutaneous Deposits with Special Consideration to Skin Reactions to Soft-Tissue Fillers....Pages 181-189 Back Matter....Pages 191-195