Class 3.4–6 Hydrolases, Lyases, Isomerases, Ligases: Ec 3.4–6 This Collection Of Datasheets Was Generated From The Database Brenda

Springer Handbook of Enzymes provides data on enzymes sufficiently well characterized. It offers concise and complete descriptions of some 5,000 enzymes and their application areas. Data sheets are arranged in their EC-Number sequence and the volumes themselves are arranged according to enzyme classes. This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes. Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications. Front Matter....Pages I-XVIII aminopeptidase S 3.4.11.24....Pages 1-28 angiotensin-converting enzyme 2 3.4.17.23....Pages 29-64 SARS coronavirus main proteinase 3.4.22.69....Pages 65-97 sortase A 3.4.22.70....Pages 98-121 sortase B 3.4.22.71....Pages 122-126 human endogenous retrovirus K endopeptidase 3.4.23.50....Pages 127-134 HycI peptidase 3.4.23.51....Pages 135-138 ADAMTS13 endopeptidase 3.4.24.87....Pages 139-180 HslU-HslV peptidase 3.4.25.2....Pages 181-202 fatty acid amide hydrolase 3.5.1.99....Pages 203-234 (R)-amidase 3.5.1.100....Pages 235-239 L-proline amide hydrolase 3.5.1.101....Pages 240-243 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5’-monophosphate deformylase 3.5.1.102....Pages 244-246 N-acetyl-1- d -myo-inositol-2-amino-2-deoxy- α - d -glucopyranoside deacetylase 3.5.1.103....Pages 247-254 peptidoglycan-N-acetylglucosamine deacetylase 3.5.1.104....Pages 255-261 chitin disaccharide deacetylase 3.5.1.105....Pages 262-266 N-formylmaleamate deformylase 3.5.1.106....Pages 267-268 maleamate amidohydrolase 3.5.1.107....Pages 269-270 UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.5.1.108....Pages 271-297 streptothricin hydrolase 3.5.2.19....Pages 298-300 5-nitroanthranilic acid aminohydrolase 3.5.99.8....Pages 301-302 Mn 2+ -dependent ADP-ribose/CDP-alcohol diphosphatase 3.6.1.53....Pages 303-308 UDP-2,3-diacylglucosamine diphosphatase 3.6.1.54....Pages 309-311 DNA helicase 3.6.4.12....Pages 312-353 RNA helicase 3.6.4.13....Pages 354-394 cyclohexane-1,2-dione hydrolase 3.7.1.11....Pages 395-396 cobalt-precorrin 5A hydrolase 3.7.1.12....Pages 397-398 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase 3.7.1.13....Pages 399-402 malonyl-S-ACP decarboxylase 4.1.1.87....Pages 403-405 biotin-independent malonate decarboxylase 4.1.1.88....Pages 406-411 biotin-dependent malonate decarboxylase 4.1.1.89....Pages 412-415 peptidyl-glutamate 4-carboxylase 4.1.1.90....Pages 416-437 3-hexulose-6-phosphate synthase 4.1.2.43....Pages 438-449 benzoyl-CoA-dihydrodiol lyase 4.1.2.44....Pages 450-452 trans- o -hydroxybenzylidenepyruvate hydratase-aldolase 4.1.2.45....Pages 453-459 aliphatic (R)-hydroxynitrile lyase 4.1.2.46....Pages 460-466 3-hydroxy- d -aspartate aldolase 4.1.3.41....Pages 467-469 (6-4)DNA photolyase 4.1.99.13....Pages 470-480 spore photoproduct lyase 4.1.99.14....Pages 481-482 S-specific spore photoproduct lyase 4.1.99.15....Pages 483-483 methanogen homoaconitase 4.2.1.114....Pages 484-489 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 4.2.1.115....Pages 490-498 3-hydroxypropionyl-CoA dehydratase 4.2.1.116....Pages 499-500 2-methylcitrate dehydratase (2-methyl-transaconitate forming)4.2.1.117....Pages 501-502 3-dehydroshikimate dehydratase 4.2.1.118....Pages 503-506 enoyl-CoA hydratase 2 4.2.1.119....Pages 507-521 4-hydroxybutanoyl-CoA dehydratase 4.2.1.120....Pages 522-526 colneleate synthase 4.2.1.121....Pages 527-531 ent-cassa-12,15-diene synthase 4.2.3.28....Pages 532-533 ent-sandaracopimaradiene synthase 4.2.3.29....Pages 534-535 ent-pimara-8(14),15-diene synthase 4.2.3.30....Pages 536-537 ent-pimara-9(11),15-diene synthase 4.2.3.31....Pages 538-539 levopimaradiene synthase 4.2.3.32....Pages 540-542 stemar-13-ene synthase 4.2.3.33....Pages 543-544 stemod-13(17)-ene synthase 4.2.3.34....Pages 545-546 syn-pimara-7,15-diene synthase 4.2.3.35....Pages 547-549 terpentetriene synthase 4.2.3.36....Pages 550-552 epi-isozizaene synthase 4.2.3.37....Pages 553-555 α -bisabolene synthase 4.2.3.38....Pages 556-559 epi-cedrol synthase 4.2.3.39....Pages 560-562 (Z)- γ -bisabolene synthase 4.2.3.40....Pages 563-564 elisabethatriene synthase 4.2.3.41....Pages 565-567 aphidicolan-16 β -ol synthase 4.2.3.42....Pages 568-569 fusicocca-2,10(14)-diene synthase 4.2.3.43....Pages 570-571 isopimara-7,15-diene synthase 4.2.3.44....Pages 572-573 phyllocladan-16 α -ol synthase 4.2.3.45....Pages 574-575 α -farnesene synthase 4.2.3.46....Pages 576-583 β -farnesene synthase 4.2.3.47....Pages 584-588 (3S,6E)-nerolidol synthase 4.2.3.48....Pages 589-592 (3R,6E)-nerolidol synthase 4.2.3.49....Pages 593-595 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 4.2.99.20....Pages 596-600 isochorismate lyase 4.2.99.21....Pages 601-608 chromopyrrolate synthase 4.3.1.26....Pages 609-610 threo-3-hydroxy- d -aspartate ammonia-lyase 4.3.1.27....Pages 611-613 carboxybiotin decarboxylase 4.3.99.2....Pages 614-616 heme ligase 4.99.1.8....Pages 617-619 hydantoin racemase 5.1.99.5....Pages 620-627 6-phospho-3-hexuloisomerase 5.3.1.27....Pages 628-633 D-sedoheptulose 7-phosphate isomerase 5.3.1.28....Pages 634-638 syn-copalyl-diphosphate synthase 5.5.1.14....Pages 639-640 terpentedienyl-diphosphate synthase 5.5.1.15....Pages 641-643 halimadienyl-diphosphate synthase 5.5.1.16....Pages 644-645 2-hydroxychromene-2-carboxylate isomerase 5.99.1.4....Pages 646-650 O-phospho- l -serine-tRNA ligase 6.1.1.27....Pages 651-660 ACP-SH:acetate ligase 6.2.1.35....Pages 661-662 3-hydroxypropionyl-CoA synthase 6.2.1.36....Pages 663-665 L-cysteine:1 d -myo-inositol 2-amino-2-deoxy- α - d -glucopyranoside ligase 6.3.1.13....Pages 666-671 diphthine-ammonia ligase 6.3.1.14....Pages 672-673 coenzyme F 420 -0: l -glutamate ligase 6.3.2.31....Pages 674-677 coenzyme γ -F 420 -2: α - l -glutamate ligase 6.3.2.32....Pages 678-680 tetrahydrosarcinapterin synthase 6.3.2.33....Pages 681-682 coenzyme F 420 -1: γ - l -glutamate ligase 6.3.2.34....Pages 683-686 D-alanine- d -serine ligase 6.3.2.35....Pages 687-689 4-phosphopantoate- β -alanine ligase 6.3.2.36....Pages 690-691 3.4.11.24 aminopeptidase S 3.4.17.23 angiotensin-converting enzyme 2 3.4.22.69 SARS coronavirus main proteinase 3.4.22.70 sortase A 3.4.22.71 sortase B 3.4.23.50 human endogenous retrovirus K Endopeptidase 3.4.23.51 HycI peptidase 3.4.24.87 ADAMTS13 endopeptidase 3.4.25.2 HslU-HslV peptidase 3.5.1.99 fatty acid amide hydrolase 3.5.1.100 (R)-amidase 3.5.1.101 L-proline amide hydrolase 3.5.1.102 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5’- monophosphate deformylase 3.5.1.103 N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-a- D-glucopyranoside deacetylase 3.5.1.104 peptidoglycan-N-acetylglucosamine Deacetylase 3.5.1.105 chitin disaccharide deacetylase 3.5.1.106 N-formylmaleamate deformylase 3.5.1.107 maleamate amidohydrolase 3.5.1.108 UDP-3-O-acyl-N-acetylglucosamine Deacetylase 3.5.2.19 streptothricin hydrolase 3.5.99.8 5-nitroanthranilic acid aminohydrolase ^ 3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol Diphosphatase 3.6.1.54 UDP-2,3-diacylglucosamine diphosphatase 3.6.4.12 DNA helicase 3.6.4.13 RNA helicase 3.7.1.11 cyclohexane-1,2-dione hydrolase 3.7.1.12 cobalt-precorrin 5A hydrolase 3.7.1.13 -hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4- dienoate hydrolase 4.1.1.87 malonyl-S-ACP decarboxylase 4.1.1.88 biotin-independent malonate decarboxylase 4.1.1.89 biotin-dependent malonate decarboxylase 4.1.1.90 peptidyl-glutamate 4-carboxylase 4.1.2.43 3-hexulose-6-phosphate synthase 4.1.2.44 benzoyl-CoA-dihydrodiol lyase 4.1.2.45 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase 4.1.2.46 aliphatic (R)-hydroxynitrile lyase 4.1.3.41 3-hydroxy-D-aspartate aldolase 4.1.99.13 (6-4)DNA photolyase 4.1.99.14 spore photoproduct lyase 4.1.99.15 S-specific spore photoproduct lyase 4.2.1.114 methanogen homoaconitase 4.2.1.115 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) ^ ^^ 4.2.1.116 3-hydroxypropionyl-CoA dehydratase 4.2.1.117 2-methylcitrate dehydratase (2-methyl-transaconitate forming) 4.2.1.118 3-dehydroshikimate dehydratase 4.2.1.119 enoyl-CoA hydratase 2 4.2.1.120 4-hydroxybutanoyl-CoA dehydratase 4.2.1.121 colneleate synthase 4.2.3.28 ent-cassa-12,15-diene synthase 4.2.3.29 ent-sandaracopimaradiene synthase 4.2.3.30 ent-pimara-8(14),15-diene synthase 4.2.3.31 ent-pimara-9(11),15-diene synthase 4.2.3.32 levopimaradiene synthase 4.2.3.33 stemar-13-ene synthase 4.2.3.34 stemod-13(17)-ene synthase 4.2.3.35 syn-pimara-7,15-diene synthase 4.2.3.36 terpentetriene synthase 4.2.3.37 epi-isozizaene synthase 4.2.3.38 a-bisabolene synthase 4.2.3.39 epi-cedrol synthase 4.2.3.40 (Z)-g-bisabolene synthase 4.2.3.41 elisabethatriene synthase 4.2.3.42 aphidicolan-16b-ol synthase 4.2.3.43 fusicocca-2,10(14)-diene synthase 4.2.3.44 isopimara-7,15-diene synthase ^ ^^ 4.2.3.45 phyllocladan-16a-ol synthase 4.2.3.46 a-farnesene synthase 4.2.3.47 b-farnesene synthase 4.2.3.48 (3S,6E)-nerolidol synthase 4.2.3.49 (3R,6E)-nerolidol synthase 4.2.99.20 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 4.2.99.21 isochorismate lyase 4.3.1.26 chromopyrrolate synthase 4.3.1.27 threo-3-hydroxy-D-aspartate ammonia-lyase 4.3.99.2 carboxybiotin decarboxylase 4.99.1.8 heme ligase 5.1.99.5 hydantoin racemase 5.3.1.27 6-phospho-3-hexuloisomerase 5.3.1.28 D-sedoheptulose 7-phosphate isomerase 5.5.1.14 syn-copalyl-diphosphate synthase 5.5.1.15 terpentedienyl-diphosphate synthase 5.5.1.16 halimadienyl-diphosphate synthase 5.99.1.4 2-hydroxychromene-2-carboxylate isomerase 6.1.1.27 O-phospho-L-serine-tRNA ligase 6.2.1.35 ACP-SH:acetate ligase 6.2.1.36 3-hydroxypropionyl-CoA synthase 6.3.1.13 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-a-D-glucopyranoside ligase ^ ^^ 6.3.1.14 diphthine-ammonia ligase 6.3.2.31 coenzyme F420-0:L-glutamate ligase 6.3.2.32 coenzyme g-F420-2:a-L-glutamate ligase 6.3.2.33 coenzyme g-F420-2:a-L-glutamate ligase 6.3.2.33 tetrahydrosarcinapterin synthase 6.3.2.34 coenzyme F420-1:g-L-glutamate ligase 6.3.2.35 D-alanine-D-serine ligase 6.3.2.36 4-phosphopantoate-b-alanine ligase. ^^ Each entry includes nomenclature, source organism, reaction and specificity, enzyme structure, isolation / preparation / mutation / application, stability, and literature references for each enzyme