Ciba Foundation Symposium 181 ‐ Neural Tube Defects: Neural Tube Defects: Ciba Foundation Symposium 181

Neural tube defects are the second most common cause of perinatal death from birth defects in the United Kingdom. In this important book, leading scientists evaluate the latest evidence on the causative factors--both genetic and environmental--of these major human congenital malformations. They also discuss prospects for early detection by prenatal screening and for treatment both before and after birth. The extensive coverage encompasses such topics as: formation and patterning of the avian neuraxis, neurulation in mammals and the normal human embryo, folic acid and more. Content: Normal Neurulation In Amphibians / A.g. Jacobson -- Formation And Patterning Of The Avian Neuraxis: One Dozen Hypotheses / G.c. Schoenwolf -- Normal Neurulation In Mammals / G. Morriss-kay, H. Wood And W.-h. Chen -- Neurulation In The Normal Human Embryo / R. O'rahilly And F. Muller -- Molecular Genetics Of Neurulation / N. Papalopulu And C.r. Kintner -- Pax Genes And Neural Tube Defects In The Mouse / M. Goulding And A. Paquette -- Genetic Models Of Mammalian Neural Tube Defects / A.j. Copp -- Valproic Acid-induced Neural Tube Defects / H. Nau -- Vitamins, Folic Acid And The Cause And Prevention Of Neural Tube Defects / M.j. Seller -- Folic Acid Metabolism And Mechanisms Of Neural Tube Defects / J.m. Scott [and Others] -- Folic Acid And Neural Tube Defects: The Current Evidence And Implications For Prevention / N.j. Wald -- Prevention Of Folic Acid-preventable Spina Bifida And Anencephaly / G.p. Oakley, Jr. [and Others] -- Spina Bifida: Anticonvulsants And Other Maternal Influences / L.b. Holmes -- Environmental Factors Affecting Neural Tube Defects -- Screening For Neural Tube Defects / H.s. Cuckle -- Meningomyelocele: Management In Utero And Post Natum / D.b. Shurtleff [and Others] -- Prevention Of Neural Tube Defects By Folic Acid Supplementation. [editors, Gregory Bock And Joan Marsh]. Symposium On Neural Tube Defects Held At The Ciba Foundation, London, 18-20 May 1993--contents P.v. Includes Bibliographical References And Index. Neural tube defects are major human congenital malformations. In this volume, scientists evaluate the latest evidence on causative factors, both genetic and environmental, and discuss prospects for early detection by prenatal screening and for treatment both before and after birth. Abstract. How does cell behaviour accomplish nueralation in amphibian embryos?