Chronic Rhinosinusitis: Pathogenesis and Medical Management (Clinical Allergy and Immunology)

Rhinosinusitis is increasing in prevalence and incidence, and has been estimated to affect approximately 31 million patients in the United States each year. This comprehensive reference offers recommendations for the optimal treatment of chronic rhinosinusitis and indicates pathways for new research in the field. Offering an interdisciplinary approach to the topic, edited by an allergist and an otolaryngologist, this source discusses advances in the understanding of the pathophysiology of the diseases, as well as important diagnostic tools for the assessment of chronic rhinosinusitis. It also summarizes published studies of chronic rhinosinusitis management for evidence-based medical care. Clinical patterns of illness and disease classification / Hamilos Impact of CRS on QOL and medical expenditure / Lund Environmental and allergic factors; experimental models / Naclerio Innate & acquired immunity and epithelial cell function / Schleimer Role of T cells and eosinophils in CRS / Hamid Role of mast cells and basophils in CRS / Pawankar Mucociliary transport in CRS / Baroody Glandular and vascular abnormalities in CRS / Baraniuk Bacterial infection and antibiotic treatment in CRS / Brook Bacteria as immune stimulant in CRS / Bachert Fungi as immune stimulant EFRS / Ponikau Radiologic assessment of CRS including image guided tech / Mafee Role of rhinoscopic assessment in medical management / Senior Role of steroids in treatment of RS +/- polyposis / Fokkens Ancillary therapies in CRS / Kaliner Classic AFS including clinical trials / Schubert Medical management of RS comorbidities / Slavin Special considerations regarding pediatric CRS / Lusk Approach to evaluation and medical management of CRS / Hamilos Interfacing medical surgical management of CRS / Baroody.