Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1 Op Paradigm

Examine the role the Eta-1/Op gene may play in uncovering the cause of CFS! Current research indicates that chronic fatigue syndrome may have an infectious etiology and that genetic factors might determine a body's ability to overcome or fall victim to a chronic infection. Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm focuses on the Early T lymphocyte activation-1/osteopontin gene (Eta-1/Op), a cytokine that offers natural resistance to bacteria, and viruses that may play a role in the suspected link between microbial infections and CFS. Written by one of the leading experts in the field, the book details the historical, clinical, and scientific aspects of Eta-1/Op and its relationship to infectious agents such as Rickettsia. Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm centers on research triggered by the high percentage of CFS patients who associate the onset of the disorder with an apparently infectious illness. This unique book addresses the role of Eta-1/Op as part of a genetic program of cellular immunity that may help in the etiopathogenesis and treatment of CFS. It also presents information on the structure and regulation of the Eta-1/Op gene and protein, and the biological activities of Eta-1/Op in nonimmunological bodily systems and pathologies. Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm includes vital information on the Eta-1/Op gene's relationship to: flaviviruses and herpesviruses mycobacterial infections and HIV infection autoimmune disease cell-cell communication cellular motility the regulation of phosphate and calcium metabolism and much more! Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm is an important addition to the continuing effort to unravel the pathogenesis of this crippling disorder. The book is an essential resource for healthcare professionals working with CFS patients and for the biomedical community as a whole. Current research indicates that chronic fatigue syndrome may have an infectious etiology and that genetic factors might determine a body's ability to overcome or fall victim to a chronic infection. Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm focuses on the early T-cell activation-1/osteopontin (Eta-1/Op) gene, a cytokine that offers natural resistance to bacteria, and viruses that may play a role in the suspected link between microbial infections and CFS. Written by one of the leading experts in the field, the book details the historical, clinical, and scientific aspects of Eta-1/Op and its relationship to infectious agents. Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm includes vital information on the Eta-1/Op gene's relationship to: flaviviruses and herpesviruses, cell-cell communication, mycobacterial infections and HIV infection, cellular motility, the regulation of phosphate and calcium metabolism, autoimmune disease, and much more! Pre-publication REVIEWS, COMMENTARIES, EVALUATIONS...; NOTES FOR PROFESSIONAL LIBRARIANS AND LIBRARY USERS; CONSERVATION AND PRESERVATION NOTES; THE HAWORTH MEDICAL PRESS℗ʾ; Publication and Copyright Information; Table of Contents; About the Author; Chapter 1 Microbial Infections, Chronic Fatigue Syndrome, and Microbial Infection Resistant Host Genes; Chapter 2 Definition of the Role of the Eta-1/Op Gene in Genetic Resistance to Bacterial and Viral Infestions; Chapter 3 Induction or Direct Use of Eta-1/Op Protein As Potential Therapy for CFS Many debilitating chronic illnesses are characterized by the presence of fatigue (Morrison, 1980), and chronic fatigue is the most commonly reported medical complaint of all patients seeking medical care (Kroenke et al., 1988). Roberto Patarca-montero. Includes Bibliographical References And Index.