Chemistry of Heterocyclic Compounds: Thiophene and Its Derivatives, Part Four, Volume 44

Physical Properties of Thiophene Derivatives (S. Gronowitz & A. Hornfeldt). Nucleophilic Substitution of Thiophene Derivatives (D. Spinelli, et al.). Biologically Active Thiophene Derivatives Revisited: 1983 1988 (J. Press). Index.Content: Chapter I Physical Properties of Thiophene Derivatives (pages 1–294): Salo Gronowitz and Anna?Britta Hornfeldt Chapter II Nucleophilic Substitution of Thiophene Derivatives (pages 295–396): Domenico Spinelli, Giovanni Consiglio, Carlo Dell'Erba and Marino Novi Chapter III Biologically Active Thiophene Derivatives Revisited: 1983–1988 (pages 397–502): Jeffery B. Press The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists. Examines the preparation of thiophenes by ring-closure reactions and from other ring systems, theoretical calculations on thiophenes, a variety of naturally occurring thiophenes, pharmacologically active thiophenes, and radical cycloaddition, and photochemical reactions of thiophenes.