Chemistry of Antibiotics and Related Drugs

This textbook discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how bacteria are becoming resistant to these antibiotics. Appropriate for a one-semester course at either the graduate or advanced undergraduate level, this textbook contains worked examples of (1) experimental procedures and (2) interpreting data. Front Matter....Pages i-xii Introduction to Antibiotics....Pages 1-25 Development of Resistance to Antibiotics....Pages 27-48 Antibiotics That Inhibit Cell Wall Synthesis....Pages 49-94 Antimetabolites: Antibiotics That Inhibit Nucleotide Synthesis....Pages 95-108 Antibiotics That Inhibit Nucleic Acid Synthesis....Pages 109-128 Antibiotics That Inhibit Protein Synthesis....Pages 129-151 Antibiotics That Affect the Membrane and Other Structural Targets....Pages 153-173 Antifungals, Antimalarials, and Antivirals....Pages 175-195 Back Matter....Pages 197-219 "This textbook discusses how the various types of antibiotics and related drugs work to cure infections. It also delves into the very serious matter of how bacteria are becoming resistant to antibiotics. Appropriate for a one-semester course at either the graduate or advanced undergraduate level, this textbook contains worked examples of experimental procedures and methods of interpreting data."--Orbis Yale University Library