Chemical warfare toxicology. volume 2, Management of poisoning / edited by Franz Worek, John Jenner and Horst Thiermann

Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents. Research efforts in various countries have resulted in novel insights into chemical warfare toxicology that has enabled the development of new approaches for the diagnosis and treatment of chemical warfare poisoning. This book provides an up-to-date treatise on the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning. Focussing on the most important representative nerve and blistering agents, whilst also covering other potential chemical warfare agents, this book will give the reader a comprehensive overview of the many different aspects of chemical warfare agent toxicology. The text will appeal to toxicologists, biochemists and weapons specialists working in industry and academia, and anyone with an interest in chemical warfare toxicology or exposure. Volume 1: Fundamental Aspects. Development, Historical Use And Properties Of Chemical Warfare Agents / Robin Black -- Toxicology Of Vesicants / John Jenner -- Toxicology Of Organophosphorus Nerve Agents / Helen Rice -- Toxicology And Treatment Of Phosgene Induced Lung Injury / Bronwen Jugg -- Human Exposures To Sulfur Mustard / John Jenner -- Long-term Effects Of The Chemical Warfare Agent Sulfur Mustard / Kai Kehe, Dirk Steinritz, Frank Balszuweit, And Horst Thiermann -- Toxicokinetics Of Sulfur Mustard / Jan P. Langenberg, Marcel J. Van Der Schans, And Daan Noort -- Modeling Organophosphorus Chemical Warfare Nerve Agents: A Physiologically Based Pharmacokinetic-pharmacodynamic (pbpk-pd) Model Of Vx / Tammier R. Covington, Lucille A. Lumley, Christopher D. Ruark, Edward D. Clarkson, Christopher E. Whalley, And Jeffery M. Gearhart -- Allometric Modeling Of Mammalian Cyanogen Chloride Inhalation Lethality / Douglas R. Sommerville. Volume 2: Management Of Poisoning. Treatment Of Nerve Agent Poisoning / Horst Thiermann, Nadine Aurbek, And Franz Worek -- Nerve Agents: Catalytic Scavengers As An Alternative Approach For Medical Countermeasures / Patrick Masson -- Nicotinic Receptors As Targets For Nerve Agent Therapy / John Tattersall -- Mustard: Pathophysiology And Therapeutic Approaches / Dirk Steinritz, Frank Balszuweit, Horst Thiermann, And Kai Kehe -- Clinical And Laboratory Diagnosis Of Chemical Warfare Agent Exposure / Franz Worke, Horst Thiermann, And Timo Wille -- Verification Of Exposure To Chemical Warfare Agents / Robert W. Read -- The Impact Of New Technologies On The Elucidation Of Chemical Warfare Agent Toxicology / Jonathan David And Harald John -- Chemical Defence Against Fentanyls / Christopher D. Lindsay, James R. Riches, Neil Roughley, And Christopher M. Timperley. Edited By Franz Worek, Bundeswehr Institute Of Pharmacology And Toxicology, Munich, Germany, John Jenner, Defence Science And Technology Laboratory, Porton Down, Uk, Horst Thiermann, Bundeswehr Institute Of Pharmacology And Toxicology, Munich, Germany. Includes Bibliographical References And Index. Mode Of Access: World Wide Web. Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents. Research efforts in various countries have resulted in novel insights into chemical warfare toxicology that has enabled the development of new approaches for the diagnosis and treatment of chemical warfare poisoning. This book provides an up-to-date treatise on the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning. Focusing on the most important representative nerve and blistering agents, whilst also covering other potential chemical warfare agents, this book will give the reader a comprehensive overview of the many different aspects of chemical warfare agent toxicology. The text will appeal to toxicologists, biochemists and weapons specialists working in industry and academia, and anyone with an interest in chemical warfare toxicology or exposure. -- Provided by publisher Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents. Research efforts in various countries have resulted in novel insights into chemical warfare toxicology that has enabled the development of new approaches for the diagnosis and treatment of chemical warfare poisoning. This book provides an up-to-date treatise on the ongoing research into the toxicology of chemical warfare agents, the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning. Focussing on the fundamentals of the toxicology of nerve agents and vesicants, this book will give the reader a comprehensive overview of the many different aspects of chemical warfare agent toxicology. The text will appeal to toxicologists, biochemists and weapons specialists working in industry and academia, and anyone with an interest in chemical warfare toxicology or exposure. Content: Volume 1: Fundamental aspects -- Volume 2: Management of poisoning.