Cerebral Venous System in Acute and Chronic Brain Injuries (Springer Series in Translational Stroke Research)

Provides important information from anatomy to pathophysiology and covers most neurological disorders that involve venous circulation. Venous circulation has not been extensively studied and we know relatively little about cerebral venous circulation. Venous circulation contributes to half of the brain circulation and about 70% of the blood in the brain is venous blood. Veins and venules play extremely important roles in brain circulation especially during pathologies such as brain edema, BBB disruption, elevation of intracranial pressure during and after ischemic and hemorrhagic stroke events, traumatic brain injury, neurodegerative disorders, in adults and newborns. Occlusion of veins or sinuses by thrombus, compression of veins and venules by tumor and edematous tissues, elevation of venous pressure during cranial hypertension, all lead to fatal insults such as venous infarction and hemorrhage. Front Matter ....Pages i-vi Neurovascular Network as Future Therapeutic Targets (Yujie Chen, Yang Zhang, Zhenni Guo, Ling Liu, Feng Gao, Yanfeng Lv et al.)....Pages 1-47 Animal Models of Venous Stroke (Qin Hu, Anatol Manaenko)....Pages 49-64 Imaging of Cerebral Vein in Acute Brain Injury (Xiaocheng Zhang, Min Lou)....Pages 65-85 Cerebral Venous Regulation (Zhenni Guo, Hang Jin, Xin Sun, Lu-Sha Tong, John H. Zhang, Yi Yang)....Pages 87-101 Cerebral Venous Collateral Circulation (Lu-Sha Tong, Yan-nan Yu, Jiping Tang, Min Lou, John H. Zhang)....Pages 103-117 Cerebral Venous System in Acute and Chronic Brain Injuries (Liang Liu, Qing-Wu Yang)....Pages 119-128 Cerebral Venous System and Implications in Neurosurgery (Yongxin Zhang, Wanling Wen, Qinghai Huang)....Pages 129-139 Pediatric Cerebral Venous Sinus Thrombosis: More Questions than Answers (Fazeel M. Siddiqui, Chirantan Banerjee)....Pages 141-148 Idiopathic Intracranial Hypertension: A Venous Disease? (Alain Lekoubou, Wuwei Feng)....Pages 149-161 The Role of Veins in Arteriovenous Malformation and Fistula, Pathophysiology and Treatment (Yongxin Zhang, Qinghai Huang)....Pages 163-172 Role of Cerebral Venous System in Hemorrhagic Stroke (Yan Qu, Lei Zhao, Hao Guo)....Pages 173-178 Role of Cerebral Venous System in Neurodegenerative Disorders (Yan Qu, Lei Zhao, Hao Guo)....Pages 179-186 Role of Cerebral Venous System in Traumatic Brain Injury (Yan Qu, Lei Zhao, Hao Guo)....Pages 187-193 Involvement of Cerebral Venous System in Ischemic Stroke (Lu-Sha Tong, Yan-nan Yu, Jiping Tang, Min Lou, John H. Zhang)....Pages 195-205 Spontaneous Thrombosis of the Main Draining Veins Revealing an Unruptured Brain Arteriovenous Malformation (Feng Yan, Gao Chen, Jianmin Zhang)....Pages 207-210 Endovascular Treatment of Cerebral Venous Sinus Thrombosis: A Literature Review (Liang Xu, Weilin Xu, Jianmin Zhang)....Pages 211-220 Functional Recovery After Cerebral Venous Thrombosis (Samir Belagaje, Wuwei Feng)....Pages 221-231 Drug Therapy of Cerebral Venous Thrombosis (Yilong Wang)....Pages 233-243 A Movement toward Precision Medicine in Acute Brain Injury: The Role of the Cerebral Venous System (Jinqi Luo, Sheng Chen, Cesar Reis, Jianmin Zhang)....Pages 245-253 This volume is focused on subjects related to cerebral veins under normal conditions and after brain injuries especially acute stroke. Some chapters are selected from the Sixth Elite Stroke meeting named Pangu Stroke Conference and some chapters are invited, but all written by members of world leading laboratories of stroke and central nervous system studies. The contents cover both clinical and bench studies, from basic components of cerebral neurovascular network and venous stroke animal models to clinical venous disorders, from venous imaging, venous regulation, and venous collateral circulation to acute and chronic brain injuries including pediatric and neurosurgical disorders to hemorrhagic stroke. Min Lou, Professor and Vice Chair of Neurology at the Second Affiliated Hospital of Zhejiang University. Jianmin Zhang, Professor and Chair of Neurosurgery at the Second Affiliated Hospital of Zhejiang University. Yilong Wang, Professor of Neurology, Beijing Tiantan Hospital. Yan Qu, Professor and Director of Neurosurgery at the Second Affiliated Hospital of Air Force Medical University, Xi'an, China. Wuwei (Wayne) Feng, Professor of Neurology Medical University of South Carolina, USA. Xunming Ji, Professor of Neurosurgery, Beijing Xuanwu Hospital. John H. Zhang, Professor of Anesthesiology and Physiology at Loma Linda University School of Medicine, Loma Linda, CA, USA